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6 records – page 1 of 1.

[Broaden health service research by looking at women's roles. Interview by Anita Widén.]

https://arctichealth.org/en/permalink/ahliterature74233
Source
Vardfacket. 1984 May 10;8(9):4-5
Publication Type
Article
Date
May-10-1984
Author
R. Wendt
Source
Vardfacket. 1984 May 10;8(9):4-5
Date
May-10-1984
Language
Swedish
Publication Type
Article
Keywords
Female
Health Services Research
Humans
Role
Sweden
Women
Work
PubMed ID
6565454 View in PubMed
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Source
Vardfacket. 1981 Mar 26;5(6):4-5
Publication Type
Article
Date
Mar-26-1981
Author
R. Wendt
Source
Vardfacket. 1981 Mar 26;5(6):4-5
Date
Mar-26-1981
Language
Swedish
Publication Type
Article
Keywords
Comprehensive Health Care
Disabled Persons
Humans
Long-Term Care
Self Care
Sweden
Terminal Care
PubMed ID
6451995 View in PubMed
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[Personal observations following TCO's data processing conference].

https://arctichealth.org/en/permalink/ahliterature245258
Source
Vardfacket. 1980 Nov 13;4(20):6-7
Publication Type
Article
Date
Nov-13-1980
Source
Tidskr Sver Sjukskot. 1975 Oct 9;42(18):4-7
Publication Type
Article
Date
Oct-9-1975
Author
R. Wendt
Source
Tidskr Sver Sjukskot. 1975 Oct 9;42(18):4-7
Date
Oct-9-1975
Language
Swedish
Publication Type
Article
Keywords
Humans
Mental Disorders - prevention & control
Mental health services
Preventive Health Services
Sweden
PubMed ID
1043417 View in PubMed
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[Research on health care in the community: neighborliness remains an expert's task]

https://arctichealth.org/en/permalink/ahliterature49428
Source
Vardfacket. 1979 Jun 8;3(11):8-11
Publication Type
Article
Date
Jun-8-1979
Author
R. Wendt
Source
Vardfacket. 1979 Jun 8;3(11):8-11
Date
Jun-8-1979
Language
Swedish
Publication Type
Article
Keywords
Environmental health
Gender Identity
Humans
Primary Health Care
Quality of Health Care
Research
Sweden
PubMed ID
258053 View in PubMed
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Supervised Classification of CYP2D6 Genotype and Metabolizer Phenotype With Postmortem Tramadol-Exposed Finns.

https://arctichealth.org/en/permalink/ahliterature298207
Source
Am J Forensic Med Pathol. 2019 Mar; 40(1):8-18
Publication Type
Journal Article
Date
Mar-2019
Author
Frank R Wendt
Nicole M M Novroski
Anna-Liina Rahikainen
Antti Sajantila
Bruce Budowle
Author Affiliation
Department of Forensic Medicine, University of Helsinki, Helsinki, Finland.
Source
Am J Forensic Med Pathol. 2019 Mar; 40(1):8-18
Date
Mar-2019
Language
English
Publication Type
Journal Article
Keywords
Analgesics, Opioid - pharmacokinetics
Cytochrome P-450 CYP2D6 - genetics
Female
Finland
Genotype
Haplotypes
Humans
Machine Learning
Male
Middle Aged
Phenotype
Polymerase Chain Reaction
Polymorphism, Single Nucleotide
Sequence Analysis, DNA
Tramadol - pharmacokinetics
Abstract
Cytochrome p450 family 2, subfamily D, polypeptide 6 (CYP2D6) may be used to infer the metabolizer phenotype (MP) of an individual as poor, intermediate, extensive/normal, or ultrarapid. Metabolizer phenotypes may suggest idiosyncratic drug responses as contributing factors to cause and/or manner of death in postmortem investigations. Application of CYP2D6 has used long-range amplification of the locus and restriction enzyme digestion to detect single-nucleotide variants (SNVs) associated with MPs. This process can be cumbersome and requires knowledge of genotype phase. Phase may be achieved using long-read DNA sequencing and/or computational methods; however, both can be error prone, which may make it difficult or impractical for implementation into medicolegal practice. CYP2D6 was interrogated in postmortem autopsied Finns using supervised machine learning and feature selection to identify SNVs indicative of MP and/or rate of tramadol O-demethylation (T:M1). A subset of 18 CYP2D6 SNVs could predict MP/T:M1 with up to 96.3% accuracy given phased data. These data indicate that phase contributes to classification accuracy when using CYP2D6 data. Of these 18 SNVs, 3 are novel loci putatively associated with T:M1. These findings may enable design of small multiplexes for easy forensic application of MP prediction when cause and/or manner of death is unknown.
PubMed ID
30507617 View in PubMed
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6 records – page 1 of 1.