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[99Tcm]MAG3 gamma camera nephrography in epidemic nephritis.

https://arctichealth.org/en/permalink/ahliterature227655
Source
Nucl Med Commun. 1991 Jan;12(1):15-25
Publication Type
Article
Date
Jan-1991
Author
R. Paul
H. Kiiliäinen
L. Tarssanen
M. Vorne
Author Affiliation
Department of Internal Medicine, Mikkeli Central Hospital, Finland.
Source
Nucl Med Commun. 1991 Jan;12(1):15-25
Date
Jan-1991
Language
English
Publication Type
Article
Keywords
Disease Outbreaks
Finland - epidemiology
Hemorrhagic Fever with Renal Syndrome - epidemiology - physiopathology
Humans
Liver - physiopathology
Oligopeptides - diagnostic use
Organotechnetium Compounds - diagnostic use
Radioisotope Renography
Technetium Tc 99m Mertiatide
Abstract
There is a lack of systematic nephrographic studies on epidemic nephritis (EN). We studied 10 patients with EN using [99Tcm]MAG3 gamma camera nephrography and followed up 9 of them 22-68 days later when they had clinically recovered. Variables for renal clearance of [99Tcm]MAG3 and the retention of radioactivity in the kidneys and blood were calculated. In all patients renal function was impaired acutely. There was marked reconstitution of renal function in the control studies. [99Tcm]MAG3 clearance was inversely related to serum creatinine. On visual inspection the nephrograms showed no focal changes. Nephrography was more sensitive than sonography at identifying renal impairment. [99Tcm]MAG3 nephrography is a sensitive method for identifying renal involvement and reconstitution of renal function in EN. It may be a valuable adjunct to the diagnostic arsenal, especially in nonendemic areas where EN occurs only sporadically and where there may be diagnostic uncertainty in patients presenting acutely with EN.
PubMed ID
1673780 View in PubMed
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Genetics of water use physiology in locally adapted Arabidopsis thaliana.

https://arctichealth.org/en/permalink/ahliterature281348
Source
Plant Sci. 2016 Oct;251:12-22
Publication Type
Article
Date
Oct-2016
Author
Julius P Mojica
Jack Mullen
John T Lovell
J Grey Monroe
John R Paul
Christopher G Oakley
John K McKay
Source
Plant Sci. 2016 Oct;251:12-22
Date
Oct-2016
Language
English
Publication Type
Article
Keywords
Adaptation, Physiological - genetics
Arabidopsis - genetics - metabolism
Chromosome Mapping
Genotype
Italy
Plant Leaves - genetics - metabolism
Quantitative Trait Loci
Sweden
Water - metabolism
Abstract
Identifying the genetic basis of adaptation to climate has long been a goal in evolutionary biology and has applications in agriculture. Adaptation to drought represents one important aspect of local adaptation, and drought is the major factor limiting agricultural yield. We examined local adaptation between Sweden and Italy Arabidopsis thaliana ecotypes, which show contrasting levels of water availability in their local environments. To identify quantitative trait loci (QTL) controlling water use physiology traits and adaptive trait QTL (genomic regions where trait QTL and fitness QTL colocalize), we performed QTL mapping on 374F9 recombinant inbred lines in well-watered and terminal drought conditions. We found 72 QTL (32 in well-watered, 31 in drought, 9 for plasticity) across five water use physiology traits: d(13)C, rosette area, dry rosette weight, leaf water content and percent leaf nitrogen. Some of these genomic regions colocalize with fitness QTL and with other physiology QTL in defined hotspots. In addition, we found evidence of both constitutive and inducible water use physiology QTL. Finally, we identified highly divergent candidate genes, in silico. Our results suggest that many genes with minor effects may influence adaptation through water use physiology and that pleiotropic water use physiology QTL have fitness consequences.
PubMed ID
27593459 View in PubMed
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Injury and disability in the professional athlete.

https://arctichealth.org/en/permalink/ahliterature234916
Source
Clin Orthop Relat Res. 1987 Aug;(221):68-76
Publication Type
Article
Date
Aug-1987
Author
R E Leach
G R Paul
Source
Clin Orthop Relat Res. 1987 Aug;(221):68-76
Date
Aug-1987
Language
English
Publication Type
Article
Keywords
Athletic Injuries - diagnosis - economics - rehabilitation
Basketball
Canada
Disability Evaluation - methods
Football
Hockey
Humans
Jurisprudence
Male
Tennis
United States
Abstract
An injury at work affects the professional athlete more than his nonathlete counterpart because it may portend the end of his playing career. The pertinent issues that concern the injured athlete are initial assessment of the injury, regulations governing treatment and rehabilitation of the injury, criteria for return-to-play status, determination of permanent impairment, and the athlete's rights. Permanent impairment determination procedures and compensation mechanisms are well established in each of the major professional leagues in the United States.
PubMed ID
3608316 View in PubMed
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