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7 records – page 1 of 1.

Etiology of mumps-like illnesses in children and adolescents vaccinated for measles, mumps, and rubella.

https://arctichealth.org/en/permalink/ahliterature176343
Source
J Infect Dis. 2005 Mar 1;191(5):719-23
Publication Type
Article
Date
Mar-1-2005
Author
Irja Davidkin
Sari Jokinen
Anja Paananen
Pauli Leinikki
Heikki Peltola
Author Affiliation
National Public Health Institute, Helsinki, Finland. irja.davidkin@ktl.fi
Source
J Infect Dis. 2005 Mar 1;191(5):719-23
Date
Mar-1-2005
Language
English
Publication Type
Article
Keywords
Adenoviridae Infections - diagnosis
Adolescent
Adult
Age Factors
Child
Child, Preschool
Enterovirus Infections - diagnosis
Epstein-Barr Virus Infections - diagnosis
Female
Finland - epidemiology
Humans
Infant
Male
Measles-Mumps-Rubella Vaccine
Paramyxoviridae Infections - diagnosis
Parotitis - virology
Parvoviridae Infections - diagnosis
Roseolovirus Infections - diagnosis
Seasons
Virus Diseases - diagnosis - epidemiology
Abstract
The possible viral etiology of mumps-like illnesses in patients vaccinated for measles, mumps, and rubella (MMR) was studied by use of serum samples prospectively collected, during 1983-1998, from 601 acutely ill Finnish children and adolescents with mumps-like symptoms. Mumps virus was excluded by testing serum samples for mumps antibodies, and the serum samples were further tested for antibodies to adenovirus, enterovirus, Epstein-Barr virus, parainfluenza virus types 1-3, and parvovirus B19. The serum samples of 114 children
PubMed ID
15688285 View in PubMed
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[Hepatitis B and vaccination program policy in Finland].

https://arctichealth.org/en/permalink/ahliterature188562
Source
Duodecim. 2002;118(1):71-2
Publication Type
Article
Date
2002
Author
Pauli Leinikki
Author Affiliation
Kansanterveyslaitos, infektioepidemiologian osasto Mannerheimintie 166, 00300 Helsinki.
Source
Duodecim. 2002;118(1):71-2
Date
2002
Language
Finnish
Publication Type
Article
Keywords
Finland - epidemiology
Hepatitis B - epidemiology - immunology - prevention & control
Hepatitis B Vaccines
Humans
Policy Making
Risk factors
Vaccination - legislation & jurisprudence - standards
PubMed ID
12229000 View in PubMed
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Maternal first-trimester enterovirus infection and future risk of type 1 diabetes in the exposed fetus.

https://arctichealth.org/en/permalink/ahliterature189221
Source
Diabetes. 2002 Aug;51(8):2568-71
Publication Type
Article
Date
Aug-2002
Author
Hanna R Viskari
Merja Roivainen
Antti Reunanen
Janne Pitkäniemi
Karita Sadeharju
Pentti Koskela
Tapani Hovi
Pauli Leinikki
Pekka Vilja
Jaakko Tuomilehto
Heikki Hyöty
Author Affiliation
Juvenile Diabetes Foundation International Center for the Prevention of type 1 diabetes in Finland and the Department of Virology, University of Tampere, Medical School, Tampere, Finland. hanna.viskari@uta.fi
Source
Diabetes. 2002 Aug;51(8):2568-71
Date
Aug-2002
Language
English
Publication Type
Article
Keywords
Antibodies, Viral - blood
Antigens, Viral - immunology
Diabetes Mellitus, Type 1 - epidemiology - etiology
Enterovirus Infections - complications
Female
Fetal Diseases - epidemiology - etiology - virology
Finland - epidemiology
Humans
Immunoenzyme Techniques
Immunoglobulin M - blood
Incidence
Pregnancy
Pregnancy Complications, Infectious - virology
Pregnancy Trimester, First
RNA, Viral - blood - isolation & purification
Viral Load
Abstract
Previous studies have suggested that enterovirus infections during pregnancy may increase the risk of type 1 diabetes in the offspring. Our aim was to evaluate the role of first trimester enterovirus infections in a larger cohort of pregnant women. Two series of pregnant women were analyzed as follows: 948 women (series 1) and 680 women (series 2) whose child developed clinical diabetes before the ages of 15 or 7 years, respectively. An equal number of control women with a nondiabetic child was selected. Acute enterovirus infections were diagnosed by measuring IgM class antibodies against coxsackievirus B5 (series 1) and a mixture of coxsackievirus B3, coxsackievirus A16, and echovirus 11 antigens (series 2). In series 2, all sera were also analyzed for IgG class antibodies against an enterovirus peptide antigen. In addition, 152 randomly selected case-control pairs and all IgM-positive mothers' sera were tested for enterovirus RNA (series 2). In series 1, 3.1% of case women had IgM antibodies against coxsackievirus B5 antigen compared with 4.1% of control women (NS). In series 2, 7.1% of case and 5.3% of control women had IgM against the mixture of enterovirus antigens (NS). IgG class enterovirus antibodies did not differ between the groups. Enterovirus RNA was found only in one case woman (0.3%) of the subgroup of samples and in 5.7% of 70 IgM-positive women. The results suggest that enterovirus infection during the first trimester of pregnancy is not associated with increased risk for type 1 diabetes in the child.
PubMed ID
12145172 View in PubMed
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[Past and present situation of HIV epidemics].

https://arctichealth.org/en/permalink/ahliterature174716
Source
Duodecim. 2005;121(6):581-2
Publication Type
Article
Date
2005

Persistence of measles, mumps, and rubella antibodies in an MMR-vaccinated cohort: a 20-year follow-up.

https://arctichealth.org/en/permalink/ahliterature157678
Source
J Infect Dis. 2008 Apr 1;197(7):950-6
Publication Type
Article
Date
Apr-1-2008
Author
Irja Davidkin
Sari Jokinen
Mia Broman
Pauli Leinikki
Heikki Peltola
Author Affiliation
National Public Health Institute, University of Helsinki, Helsinki, Finland. irja.davidkin@ktl.fi
Source
J Infect Dis. 2008 Apr 1;197(7):950-6
Date
Apr-1-2008
Language
English
Publication Type
Article
Keywords
Antibodies, Viral - analysis - blood
Child
Cohort Studies
Female
Finland
Follow-Up Studies
Humans
Immunization, Secondary
Immunoenzyme Techniques - methods
Infant
Male
Measles - prevention & control
Measles-Mumps-Rubella Vaccine - immunology
Mouth - immunology
Mumps - prevention & control
Rubella - prevention & control
Time Factors
Abstract
The persistence of antibodies against measles, mumps, and rubella induced by the measles-mumps-rubella (MMR) vaccine and the kinetics of antibody decline after the second MMR vaccine dose were studied in the same cohort for 20 years.
Measles, mumps, and rubella antibodies were measured by enzyme immunoassay in 20-year follow-up serum samples (n= 183) of twice-vaccinated individuals, and measles antibodies were also measured in oral fluids (n = 177). Antibody decay was determined in a group (n = 58) with subsequent samples collected 1, 8, and 15 years after the second MMR dose.
In total, 95%, 74%, and 100% of 183 vaccinees were still seropositive for measles, mumps, and rubella, respectively, and 85% of 177 vaccinees had measurable measles antibodies in their oral fluids. The antibody levels declined significantly after the second dose, but subsequently the rate of decline was slower.
A high rate of seropositivity was found 20 years after the first MMR dose, particularly for rubella and measles. Our results show that MMR vaccine-induced antibodies wane significantly after the second dose. According to epidemiological data, the protection induced by MMR vaccination in Finland seems to persist at least until early adulthood. However, the situation requires constant vigilance.
PubMed ID
18419470 View in PubMed
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7 records – page 1 of 1.