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[Bone mineral density and occurrence of fractures in 66-year old women in Oslo].

https://arctichealth.org/en/permalink/ahliterature220876
Source
Tidsskr Nor Laegeforen. 1993 Jun 10;113(15):1846-8
Publication Type
Article
Date
Jun-10-1993
Author
J. Halse
K P Nordal
J. Knudtzon
O. Stokke
E. Glattre
Author Affiliation
Medisinsk avdeling B, Rikshospitalet, Oslo.
Source
Tidsskr Nor Laegeforen. 1993 Jun 10;113(15):1846-8
Date
Jun-10-1993
Language
Norwegian
Publication Type
Article
Keywords
Adult
Aged
Bone Density
Female
Fractures, Bone - epidemiology - etiology - metabolism
Humans
Middle Aged
Norway - epidemiology
Osteoporosis, Postmenopausal - complications - metabolism
Abstract
During 1991 we examined 196 randomly chosen females born in 1925 and resident in Oslo. 40% had suffered fractures of the appendicular skeleton, most commonly of the forearm and the ankles, after the menopause. Results from bone mineral density measurements of the lumbar spine (L2-4) and the femoral neck were not significantly lower, while results from the distal 1/3 of the forearm site were significantly lower, among participants with fractures than among participants without fractures. The values for bone mineral density obtained from these three sites corresponded with the values reported from other countries. Biochemical indices of calcium metabolism were similar in fracture and non-fracture subjects. Age at menopause, weight, height and demographic characteristics were also similar in the two groups. We conclude that low bone mineral density cannot be the sole explanation of the very high prevalence of fractures among female residents of Oslo found in the present and previous studies.
PubMed ID
8322323 View in PubMed
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[Doxazosin (Carduran)--a research survey]

https://arctichealth.org/en/permalink/ahliterature52997
Source
Tidsskr Nor Laegeforen. 1993 Feb 28;113(6):693-9
Publication Type
Article
Date
Feb-28-1993
Author
H P Stokke
P. Fauchald
I. Holme
H E Rugstad
B O Christophersen
O. Stokke
Author Affiliation
Medisinsk avdeling B, Rikshospitalet, Oslo.
Source
Tidsskr Nor Laegeforen. 1993 Feb 28;113(6):693-9
Date
Feb-28-1993
Language
Norwegian
Publication Type
Article
Keywords
Aged
Doxazosin - adverse effects - therapeutic use
Drug Evaluation
English Abstract
Female
Follow-Up Studies
Humans
Hypertension - blood - drug therapy - mortality
Lipoproteins, HDL Cholesterol - blood
Male
Middle Aged
Norway
Abstract
4,260 patients were included in an open surveillance study simultaneously with the introduction of doxazosin for treatment of essential hypertension in Norway. The main aim of the study was to systematically collect information on side effects and events in patients being treated with a new drug. The effect on blood pressure, heart rate and lipids was also recorded. The study lasted for one year. 21 deaths were reported. 53% of the patients reported side effects and/or events. The frequency of side effects was particularly high during the first month of treatment. No new types of side effects were found. The initial higher frequency of reported side effects referred to all organ systems, and was also of the same magnitude in the different systems. A relation was found between certain cardiac side effects and/or events and cessation of previous medication upon starting treatment with doxazosin. The study shows that certain safety precautions should be observed in patients with coronary heart disease and heart failure. In three patients, doxazosin should be used only in combination with more specific treatment. Special caution should be observed when changing the specific basic treatment. Doxazosin had a very favourable antihypertensive effect. A drop in cholesterol and triglycerides was observed, as expected. The HDL-cholesterol value declined, which was unexpected. The results are difficult to interpret, owing to lack of a control group. On the other hand, the study shows how high blood pressure is being treated with drugs in ordinary practice. The authors discuss the methodology of surveillance studies.
Notes
Comment In: Tidsskr Nor Laegeforen. 1993 Oct 20;113(25):31627903829
PubMed ID
8465331 View in PubMed
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[Medical treatment of back problems--10 times more expensive than treatment by chiropractors].

https://arctichealth.org/en/permalink/ahliterature224346
Source
Tidsskr Nor Laegeforen. 1992 Feb 10;112(4):526
Publication Type
Article
Date
Feb-10-1992
Author
O. Stokke
Source
Tidsskr Nor Laegeforen. 1992 Feb 10;112(4):526
Date
Feb-10-1992
Language
Norwegian
Publication Type
Article
Keywords
Back Pain - economics - therapy
Chiropractic - economics
Humans
Norway
PubMed ID
1532465 View in PubMed
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