The article presents results obtained in study of relationship between polymorph variants of CYP1A1 and CYP1A2 genes with reproductive and thyroid diseases risk in female workers of petrochemical industry, when compared with reference group females. Variants TD and DD of CYP1A2 gene appeared to be associated with nodes formation in uterus and breast in female workers and reference group females. Following liability markers are obtained: homozygous in rare allele genotype CC of CYP1A1 gene for reproductive and thyroid diseaes (fibrous cystic mastopathy and nodular goitre), heterozygous genotype AG of CYP1A1 gene in uterine myoma and fibrous cystic mastopathy, homozygous in deleted T genotype of CYP1A2 gene in autoimmune thyroiditis. Occupational hazards and long length of service at hazardous industries increase effects of rare alleles of the genes studied.
The legal and ethical issues related with the protection of population reproductive health, under the conditions of anthropogenic contamination of the environment, including the labor environment, are discussed in the article. A concept of pregnancy planning to ensure a healthy posterity under the mentioned conditioned was formulated. Documents of WHO, ILO and the EU experience in dealing with the issues in question are illustrated. An increasing role of social labor measurement as well as the evolution of law, i.e. civil, labor, and social law, as well as the right to unified medical-and-social insurance, are in the focus of attention. The prospects for a new WHO-ICF classification, as a social UNO classification, are pointed out. The sensitivity--susceptibility--vulnerability chain was analyzed, and a growing social context was underlined in it. The individual and team risks were considered, and the Code of professional ethics of hygienists was paid attention to.
The issues and prospects of workers' reproductive health as a problem of occupational health in nowadays Russia are outlined with due account for WHO, ILO, EC, etc. concepts and recommendations. Main principles of reproductive health protection are gender approach, additional protection of vulnerable groups, e. g. pregnant women and obligatory account for combined effects of occupational, environmental and socio-economic risk factors. Two groups of criteria are essential: criteria of health and criteria of emancipation. Criteria for evaluation of reproductive health disorders are worked out based on official statistical indices and it is proposed to rate some of these as of extra category class for effective risk assessment and risk management. The strategy and priorities in workers' reproductive health are discussed and need for international cooperation is noted for resolving this problem.
Development of information society engenders the problem of hygienic regulation of information load for the population, first of all for vulnerable groups. There are presented international and Russian normative legal documents and experience in this area, there are described the negative effects of information (such as stress, depression, suicidal ideations). There are considered social-psychological characteristics of vulnerable groups that requires their best protection from loads of information, doing harm, particularly in terms of reproductive health, family relationships, children, etc. There was noted the desirability of improvement of sanitary, legislation on the regulation of the information load on the population, especially in vulnerable groups, in terms of optimization of parameters of the signal-carriers on volume, brightness and the adequacy of the volume and content of information in radio and television broadcasting, in an urban environment and at the plant to preserve the health and well-being of the population.
The article deals with various aspects of workers' reproductive health care during economic crisis in Russia. Deterioration of health state in children and adults threatens deeper negative demographic trends. The authors discuss basic principles of "Reproductive health as a problem in occupational medicine". Concept and suggest measures aimed to preserve and improve health of Russian population.
The article covers analysis and summary of data on occupational traumatism among female workers engaged into various economic branches of RF. The authors analysed distribution of victims according to occupational accident types, causes of traumatism, studied dependence on the victims' age and length of service, followed the relationships with possible reproductive disorders.
Problems of ecology do not affect nations individually. Similarly, scientists must participate in seeking solutions to ecologic problems regardless of State borders. The sophistication of certain demographic indices, primarily those of infant and maternal mortality and of population reproduction, is a barometer of a nation's socioeconomic status and the quality of medical care. Solutions to practical problems in the field of public health are based on scientific research conducted on various problems. A task of urgent priority in Russia is to solve the problems of maintaining health, particularly reproductive, and preventing health disorders. It is the generation of the 1980s and 1990s that faces the basic difficulties of reestablishing the Russian State. We offer for our colleagues' discussion the basic directions of scientific research planned in the Russian Federation to find points of contact with respect to this problem within the framework of possible cooperation.