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[Mechanisms of the development of anemia in stomach cancer]

https://arctichealth.org/en/permalink/ahliterature17676
Source
Vopr Onkol. 2004;50(2):208-13
Publication Type
Article
Date
2004
Author
E A Stenovaia
V V Novitskii
N V Riazantseva
S B Tkachenko
V E Goldberg
Author Affiliation
Siberian Medical University, Ministry of Health of the RF, Tomsk.
Source
Vopr Onkol. 2004;50(2):208-13
Date
2004
Language
Russian
Publication Type
Article
Keywords
Adult
Aged
Anemia - blood - etiology
Chromatography, Liquid
Cytophotometry
Electrophoresis
English Abstract
Erythrocyte Membrane - metabolism - pathology
Erythrocytes - metabolism
Female
Humans
Interferometry
Male
Microscopy, Electron, Scanning Transmission
Middle Aged
Stomach Neoplasms - blood - complications
Abstract
Structural and metabolic statuses of erythrocytes were evaluated using cytophoto- and interferometry, fine-layer chromatography, scanning and transmission electron microscopy, electrophoresis and fluorescent probing in 48 stomach cancer patients. Structural and metabolic disorders were detected in mature erythrocytes in patients with and without anemia. Changes in the structure and metabolism of peripheral blood erythrocytes taking place prior to quantitative changes were identified. Anemia development pathways were dependent on enhanced hemolysis of circulating erythrocytes and influx of immature cells from the bone marrow. The changing statuses of the membranes and metabolism appeared to play quite a role in erythrons being damaged by tumor process. Dysfunctional erythrocytes of stomach cancer patients need to be corrected by membrane-stabilizing and -repairing drugs.
PubMed ID
15176225 View in PubMed
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[Population association features of interleukine gene polymorphism in khakases with gastroduodenal diseases].

https://arctichealth.org/en/permalink/ahliterature135007
Source
Ter Arkh. 2011;83(2):16-9
Publication Type
Article
Date
2011
Author
E S Ageeva
O V Shtygasheva
N V Riazantseva
Source
Ter Arkh. 2011;83(2):16-9
Date
2011
Language
Russian
Publication Type
Article
Keywords
Adolescent
Adult
Alleles
DNA - genetics
Duodenal Diseases - blood - ethnology - genetics
Ethnic Groups
Female
Genetic Predisposition to Disease
Genotype
Humans
Interleukins - blood - genetics
Male
Middle Aged
Polymerase Chain Reaction
Polymorphism, Genetic
Prevalence
Russia - epidemiology
Stomach Diseases - blood - ethnology - genetics
Young Adult
Abstract
To investigate association of polymorphisms of IL-1 genes and antagonist of IL-2 receptor (IL1Ra).
Patients with chronic gastritis and ulcer were examined using the method of restriction analysis.
It was found that CCILbeta and R4/R4IL1Ra are most prevalent allel variants in khakas population.
It is expedient to define population risk and protective genotypes of development of ulcer associated with Helicobacter pylori in khakases.
PubMed ID
21516843 View in PubMed
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[Specific features of erythrocyte membranes and metabolism in patients with lung cancer]

https://arctichealth.org/en/permalink/ahliterature17770
Source
Vopr Onkol. 2004;50(1):63-7
Publication Type
Article
Date
2004
Author
E A Stepovaia
V V Novitskii
V E Goldberg
N V Riazantseva
S B Tkachenko
M V Kolosova
Author Affiliation
Siberian State Medical University, Ministry of Health of the RF, Tomsk.
Source
Vopr Onkol. 2004;50(1):63-7
Date
2004
Language
Russian
Publication Type
Article
Keywords
Adult
Aged
Anemia - blood - etiology - pathology
Carcinoma, Non-Small-Cell Lung - blood
Carcinoma, Small Cell - blood
English Abstract
Erythrocyte Membrane - metabolism - pathology
Humans
Incidence
Lung Neoplasms - blood - complications - pathology
Male
Middle Aged
Neoplasm Staging
Abstract
A study of erythrocyte metabolism and membrane status has identified the structurally and metabolically deranged mature erythrocytes, both in anemic and anemia-free patients with stage III-IV lung cancer. Anemia incidence in non-small-cell lung cancer was significantly higher than in the small-cell lung cancer group.
PubMed ID
15088524 View in PubMed
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