Skip header and navigation

Refine By

13 records – page 1 of 2.

Biochemical and clinical effects of an antioxidative supplementation of geriatric patients. A double blind study.

https://arctichealth.org/en/permalink/ahliterature231059
Source
Biol Trace Elem Res. 1989 Apr-May;20(1-2):135-51
Publication Type
Article
Author
J. Clausen
S A Nielsen
M. Kristensen
Author Affiliation
Institute of Life Sciences and Chemistry, University of Roskilde, Denmark.
Source
Biol Trace Elem Res. 1989 Apr-May;20(1-2):135-51
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Antioxidants - pharmacology - therapeutic use
Cerebrovascular Circulation
Clinical Trials as Topic
Denmark
Double-Blind Method
Emotions - drug effects
Erythrocytes - enzymology
Fatty Acids - blood
Female
Glutathione Peroxidase - blood
Hemoglobins - analysis
Humans
Lipofuscin - blood
Male
Psychomotor Performance - drug effects
Selenium - blood
Vitamin E - blood
Abstract
Ninety seven geriatric patients from two Danish homes for old people accepted to participate in a blinded experiment designed to counteract ageing phenomena. The subjects were split into two groups, i.e., the verum and the placebo group. The verum group received daily for one year an antioxidative cocktail consisting of: 300 micrograms selenium as L-selenomethionine, 45 mg zinc, 270 mg vitamin C, 2.7 mg vitamin A, 6 mg vitamin B-6, and 465 mg vitamin E (d-alfatocopherol). Furthermore, in order to enhance exchange in polyenoic acids, each subject received daily 250 mg gamma-linolenic acid. The placebo groups received similar looking pills and capsules without the active components. During one year in the verum group, the whole blood selenium, the hydrogen-dependent glutathione peroxidase (GSH-Px) of erythrocytes, and the vitamin E level in serum was found increased compared to the pretreatment values and to the placebo group. No change could be traced in the t-butylhydroperoxide dependent GSH-Px, an enzyme that also assays the glutathione-s-transferase. During the same period of time, the fasting levels of serum fatty acids and the content of lipofuscin in erythrocytes were estimated. Compared to the pretreatment values, the lipofuscin level declined significantly and the level of w-3 penta- and hexaenoic acids increased in the verum, but not in the placebo group. During the study period, slight, but significant improvements in psychological scores could be traced. Furthermore, the assays of bloodflow in different areas of the brain surface (i.e., the ISI values) revealed a general trend to improvement in all areas, when the ISI values were compared during treatment with the pretreatment values and the values in the placebo group.
PubMed ID
2484393 View in PubMed
Less detail

A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia.

https://arctichealth.org/en/permalink/ahliterature46604
Source
Acta Psychiatr Scand. 1992 Aug;86(2):138-45
Publication Type
Article
Date
Aug-1992
Author
A L Nyth
C G Gottfries
K. Lyby
L. Smedegaard-Andersen
J. Gylding-Sabroe
M. Kristensen
H E Refsum
E. Ofsti
S. Eriksson
S. Syversen
Author Affiliation
Department of Psychiatry and Neurochemistry, University of Göteborg, Mölndal Hospital, Sweden.
Source
Acta Psychiatr Scand. 1992 Aug;86(2):138-45
Date
Aug-1992
Language
English
Publication Type
Article
Keywords
Aged
Citalopram - pharmacokinetics - therapeutic use
Cognition - drug effects
Comparative Study
Dementia - psychology
Depressive Disorder - complications - drug therapy - psychology
Double-Blind Method
Humans
Placebos
Abstract
A total of 149 patients in 7 centers in Denmark, Norway and Sweden entered a 6-week double-blind trial intended to assess the antidepressant effect and safety of citalopram vs placebo in depressed elderly patients (65 years of age or older) who might also suffer from somatic disorders and/or senile dementia. Results of ratings on the Hamilton Rating Scale for Depression, the Montgomery-Asberg Depression Rating Scale and the Clinical Global Impression Scale provided consistent evidence that the citalopram-treated patients improved more than the placebo-treated patients. Results of ratings on the Gottfries-Bråne-Steen dementia rating scale indicated that both cognitive and emotional functioning improved significantly more in the citalopram-treated subgroup of patients with dementia than in the placebo-treated subgroup.
PubMed ID
1529737 View in PubMed
Less detail

The Danish EPR Observatory. Assessing organisational impact from EPR implementation.

https://arctichealth.org/en/permalink/ahliterature195904
Source
Stud Health Technol Inform. 2000;77:627-31
Publication Type
Article
Date
2000
Author
M. Kristensen
C. Nøhr
S K Andersen
Author Affiliation
Department of Development and Planning, Aalborg University, Denmark.
Source
Stud Health Technol Inform. 2000;77:627-31
Date
2000
Language
English
Publication Type
Article
Keywords
Denmark
Diffusion of Innovation
Humans
Medical Records Systems, Computerized
National Health Programs
Patient care team
Abstract
The EPR Observatory has studied 13 local Danish electronic patient record (EPR) projects through 2 years. The focus has been on expectations and experiences in relation to organisational changes. The main conclusions are that the healthcare professionals, working with the development, implementation and/or use of EPR, are in a very important and difficult process settling up with old traditions and cultures tied to the healthcare professions. Especially the healthcare professionals, working with EPR, shows interest and readiness to participate in new ways of collaboration and to work with highly structured data in structured frameworks. EPR is at this point of time only diffused in few relatively small and isolated healthcare organisations, and the preliminary assessment in the study only outlines the perspectives for what will happen on a wider scale when EPR systems get more diffused.
PubMed ID
11187629 View in PubMed
Less detail

Dietary intake of whole grains and plasma alkylresorcinol concentrations in relation to changes in anthropometry: the Danish diet, cancer and health cohort study.

https://arctichealth.org/en/permalink/ahliterature291645
Source
Eur J Clin Nutr. 2017 08; 71(8):944-952
Publication Type
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Date
08-2017
Author
C Kyrø
M Kristensen
M U Jakobsen
J Halkjær
R Landberg
Hb As Bueno-de-Mesquita
J Christensen
I Romieu
A Tjønneland
A Olsen
Author Affiliation
Unit of Diet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark.
Source
Eur J Clin Nutr. 2017 08; 71(8):944-952
Date
08-2017
Language
English
Publication Type
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Alkylation
Biomarkers - blood
Cohort Studies
Cross-Sectional Studies
Denmark - epidemiology
Female
Follow-Up Studies
Healthy Diet - ethnology
Humans
Male
Middle Aged
Overweight - blood - epidemiology - ethnology - prevention & control
Patient Compliance - ethnology
Prospective Studies
Resorcinols - blood
Risk
Secale
Self Report
Sex Factors
Triticum
Waist Circumference - ethnology
Weight Gain - ethnology
Whole Grains
Abstract
Whole grain intake has been associated with a small but significant lower body weight gain in observational studies, but there is limited knowledge about the associations with specific whole grain types. The objective was to investigate the association between whole grains, different sources of whole grains and biomarkers of whole grain intake (alkylresorcinols) in relation to subsequent changes in waist circumference (WC) and body weight.
Cohort study of 57?053 participants with baseline information on whole grain intake from questionnaires (FFQ) and biomarkers of whole grain rye and wheat intake, plasma alkylresorcinols, for a subset. WC and body weight were measured at baseline and again at follow-up. The associations were estimated using multiple linear regression analyses and logistic regression.
For women, overall whole grain intake was not related to changes in WC or body weight. For men, total whole grain intake was associated with gains in WC (?WC per 25?g increment: 0.44?cm, 95% CI: 0.34?cm; 0.54?cm) and body weight (?weight per 25?g increment: 150?g, 95% CI: 78?g; 222?g), but the results changed to null or changed direction when adjusting for baseline anthropometry. For the different sources of whole grains, rye (women) and crispbread was significantly associated with gains in WC and body weight. Plasma alkylresorcinol concentration was associated with reduced WC, but not body weight, for women (?WC per 50?nmol/l increment: -0.69?cm, 95% CI:-1.26?cm;-0.13?cm), but no association was found for men.
Overall, no strong relationship between whole grain intake, measured from questionnaires or using biomarkers was found in relation to changes in body weight and WC.
Notes
Cites: Am J Clin Nutr. 2006 Oct;84(4):789-97 PMID 17023705
Cites: Am J Clin Nutr. 2003 Nov;78(5):920-7 PMID 14594777
Cites: Scand J Public Health. 2007;35(4):432-41 PMID 17786808
Cites: J Nutr. 2005 Sep;135(9):2263-70 PMID 16140909
Cites: J Nutr. 2005 Mar;135(3):580-3 PMID 15735097
Cites: Proc Nutr Soc. 2003 Feb;62(1):129-34 PMID 12740067
Cites: J Nutr Metab. 2012;2012:462967 PMID 22363838
Cites: Epidemiology. 2015 Jan;26(1):122-9 PMID 25401453
Cites: Br J Nutr. 2009 Dec;102(11):1547-51 PMID 19622189
Cites: Scand J Public Health. 2012 Feb;40(1):76-84 PMID 21976053
Cites: Am J Clin Nutr. 2013 Oct;98(4):872-84 PMID 23945718
Cites: Br J Nutr. 2014 May 28;111(10):1881-90 PMID 24521535
Cites: World Health Organ Tech Rep Ser. 2000;894:i-xii, 1-253 PMID 11234459
Cites: Public Health Nutr. 2011 Oct;14 (10 ):1787-95 PMID 21338557
Cites: Appetite. 2011 Dec;57(3):707-10 PMID 21907743
Cites: BMC Public Health. 2009 Mar 25;9:88 PMID 19320986
Cites: Physiol Behav. 2012 Feb 1;105(3):877-84 PMID 22061429
Cites: J Am Diet Assoc. 2009 Aug;109 (8):1356-66 PMID 19631041
Cites: Anal Biochem. 2009 Feb 1;385(1):7-12 PMID 19010298
Cites: Am J Epidemiol. 2014 May 15;179(10):1188-96 PMID 24699786
Cites: Am J Clin Nutr. 2008 Apr;87(4):832-8 PMID 18400704
Cites: Br J Nutr. 2004 Oct;92 (4):735-48 PMID 15522143
Cites: Am J Epidemiol. 2005 Aug 1;162(3):267-78 PMID 15987729
Cites: Food Nutr Res. 2013 Dec 12;57:null PMID 24358035
Cites: Am J Clin Nutr. 2009 Jan;89(1):290-6 PMID 19056600
Cites: Int J Epidemiol. 1991 Dec;20(4):906-12 PMID 1800429
Cites: J Natl Cancer Inst. 2014 Jan;106(1):djt352 PMID 24317181
Cites: Am J Clin Nutr. 1997 Apr;65(4 Suppl):1220S-1228S; discussion 1229S-1231S PMID 9094926
Cites: Am J Clin Nutr. 2013 Feb;97(2):344-53 PMID 23269820
Cites: Am J Clin Nutr. 2013 Aug;98(2):594-619 PMID 23803885
Cites: Int J Epidemiol. 1991 Dec;20(4):900-5 PMID 1800428
Cites: Am J Clin Nutr. 2004 Nov;80(5):1237-45 PMID 15531671
Cites: J Agric Food Chem. 2004 Dec 29;52(26):8242-6 PMID 15612824
PubMed ID
28176776 View in PubMed
Less detail

[Freezing of human embryos: the first Danish results]

https://arctichealth.org/en/permalink/ahliterature64793
Source
Ugeskr Laeger. 1993 Aug 16;155(33):2523-5
Publication Type
Article
Date
Aug-16-1993
Author
S. Lindenberg
M. Kristensen
S L Smidt-Jensen
H K Krog
Author Affiliation
Fertilitetsklinikken, Frederiksberg.
Source
Ugeskr Laeger. 1993 Aug 16;155(33):2523-5
Date
Aug-16-1993
Language
Danish
Publication Type
Article
Keywords
Cryopreservation - methods
Denmark
Embryo Transfer
English Abstract
Ethics, Medical
Female
Fertilization in Vitro
Freezing
Humans
Legislation, Medical
Pregnancy
Prospective Studies
Abstract
The first human pregnancies reported in Denmark following in vitro fertilization and embryo transfer of frozen and thawn embryos are presented. A total of nine embryo transfers, with a mean of one point eight embryos per transfer, were carried out, resulting in three singleton pregnancies. The benefits for the infertile couple, the ethics and technical aspects are discussed with respect to Danish legislation.
PubMed ID
8212354 View in PubMed
Less detail
Source
Ugeskr Laeger. 1996 Oct 21;158(43):6085-9
Publication Type
Article
Date
Oct-21-1996
Author
P. Bjerregaard
L M Kristensen
J. Kiil-Nielsen
B. Egelund
I K Kollemorten
Author Affiliation
Qasigiannguit Sygehus, Dansk Institut for Klinisk Epidemiologi, København.
Source
Ugeskr Laeger. 1996 Oct 21;158(43):6085-9
Date
Oct-21-1996
Language
Danish
Publication Type
Article
Keywords
Abortion Applicants
Abortion, Induced - statistics & numerical data
Contraception Behavior
Family Planning Services
Female
Greenland - epidemiology - ethnology
Health Knowledge, Attitudes, Practice
Humans
Pregnancy
Prospective Studies
Questionnaires
Socioeconomic Factors
Abstract
The purpose of the study was to seek knowledge about the reasons for the very high rate of legal abortions in Greenland. In four municipalities in the Disko Bay region of West Greenland all pregnant women were asked to fill in a questionnaire. Due to organisational problems only 39% of the women were asked to participate and a total of 82 women seeking abortion and 175 women who wished to continue the pregnancy were enrolled in the study. A few Danish women (22) were subsequently removed from the study base. The women who wanted an abortion were more often than the other women single, their knowledge of Danish as a second language was poorer, and they less often had a job. Although the age distributions of the two groups were similar the women who wanted an abortion had more often been pregnant before (more births and more abortions). The women who wanted an abortion more often than the other women reported having been drunk, having had a pelvic inflammation or VD, and having been admitted to hospital. Half of the women who wanted an abortion reported that they had forgotten to use their contraception and one fourth were opposed to the use of contraception. There seems not to be a well defined high risk group for legal abortion but a general need for a more realistic view on contraception.
PubMed ID
8928293 View in PubMed
Less detail

[Management structure. New, "audacious" thoughts in committee's report are quite superficial. Interview by Helle Kastholm Hansen].

https://arctichealth.org/en/permalink/ahliterature239037
Source
Sygeplejersken. 1985 Mar 20;85(12):14-6
Publication Type
Article
Date
Mar-20-1985

[Management structure. Nursing is a helping function for patients].

https://arctichealth.org/en/permalink/ahliterature239976
Source
Sygeplejersken. 1984 Oct 24;84(43):15-6
Publication Type
Article
Date
Oct-24-1984
Author
K M Kristensen
Source
Sygeplejersken. 1984 Oct 24;84(43):15-6
Date
Oct-24-1984
Language
Danish
Publication Type
Article
Keywords
Administrative Personnel
Denmark
Humans
Nurse Administrators
Nursing Services - organization & administration
Physicians
PubMed ID
6570764 View in PubMed
Less detail

[Open nursing care plan. Risk for violation of the law].

https://arctichealth.org/en/permalink/ahliterature228367
Source
Sygeplejersken. 1990 Sep 19;90(38):18-9
Publication Type
Article
Date
Sep-19-1990
Author
M. Kristensen
Source
Sygeplejersken. 1990 Sep 19;90(38):18-9
Date
Sep-19-1990
Language
Danish
Publication Type
Article
Keywords
Communication
Confidentiality - legislation & jurisprudence
Denmark
Humans
Nursing Records
Patient Care Planning
PubMed ID
2080452 View in PubMed
Less detail

Shared experience in 13 local Danish EPR projects: the Danish EPR Observatory.

https://arctichealth.org/en/permalink/ahliterature192899
Source
Stud Health Technol Inform. 2001;84(Pt 1):670-4
Publication Type
Article
Date
2001
Author
C. Nøhr
M. Kristensen
S K Andersen
S. Vingtoft
S. Lippert
K. Berstein
M. Bruun-Rasmussen
Author Affiliation
Department of Development and Planning, Aalborg University, Aalborg, Denmark. CN@i4.auc.dk
Source
Stud Health Technol Inform. 2001;84(Pt 1):670-4
Date
2001
Language
English
Publication Type
Article
Keywords
Attitude to Computers
Computer Security
Denmark
Health Policy
Hospital Administration
Hospital Information Systems - organization & administration
Humans
Medical Records Systems, Computerized - organization & administration
Organizational Innovation
Questionnaires
Systems Integration
Abstract
In 1996 a national strategy for the development of electronic patient records (EPR) for the Danish hospitals and primary care was launched. An element in the strategy was to support a number of regional EPR development projects. The EPR-Observatory has in the two recent years collected data from the regional projects, dealing with the expectations in four areas: 1) Impact on organisational issues, 2) Benefits of EPR, 3) Integration of EPR with other information systems and 4) security aspects of EPR. Among the observations an increasing teamwork and im-proved knowledge about the patient was found. What was expected, but not found, was resistance to EPR, as a result of changes in skills and power. The most obvious benefits are increased data accessibility and improved decision ma-king. The most considerable disadvantage is an enormous growth in discontent with the systems performance and the fact, that all the projects are delayed. Many different types of integration solutions are chosen, because of a lack of a common model for integration. Generally the projects find, that EPJ yields increased security, but logistical problems arise in having the systems running 24 hours 7 days a week. Economical benefits cannot be documented. This relates to the fact, that the regional projects are stand-alone projects. The ongoing growth in discontent with the EPR-systems and the fact, that all the projects are delayed must be subject to further exploration.
PubMed ID
11604822 View in PubMed
Less detail

13 records – page 1 of 2.