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The concept of corticosteroid cataractogenic factor revisited.

https://arctichealth.org/en/permalink/ahliterature227964
Source
Can J Ophthalmol. 1990 Dec;25(7):345-7
Publication Type
Article
Date
Dec-1990
Author
C. Fournier
J A Milot
M J Clermont
S. O'Regan
Author Affiliation
Department of Ophthalmology, Hôpital Sainte-Justine, Montreal, PQ.
Source
Can J Ophthalmol. 1990 Dec;25(7):345-7
Date
Dec-1990
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Canada - epidemiology
Cataract - chemically induced - epidemiology
Child
Child, Preschool
Female
Graft Rejection - drug effects
HLA Antigens - immunology
Histocompatibility testing
Humans
Incidence
Kidney Transplantation - immunology
Male
Prednisone - adverse effects - therapeutic use
Visual acuity
Abstract
Formation of posterior subcapsular cataracts is a known complication of systemic corticosteroid therapy. However, the relation between steroid dosage, cumulative dose and type of steroid on one hand and the subsequent formation of cataract on the other is unclear. We carried out a study to determine the incidence of posterior subcapsular cataracts in 64 children who had undergone renal transplantation and to attempt to determine what factors were associated with cataract formation. Cataracts were detected in 17 (26%) of the patients. The steroid dosage, cumulative dose and duration of therapy were not associated with cataract formation. There was a significant difference in the distribution of HLA-CW3 antigen between the patients with cataracts and those without cataracts. The reason for the link between corticosteroid therapy and formation of posterior subcapsular cataracts remains unclear.
PubMed ID
2090339 View in PubMed
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[Development of organ transplantation in Quebec from 1985 to January 1990].

https://arctichealth.org/en/permalink/ahliterature227581
Source
Ann Chir. 1991;45(9):791-5
Publication Type
Article
Date
1991
Author
J. Corman
M J Clermont
R. Dandavino
P. Daloze
J G Lachance
R. Mangel
J. Corcos
C. Chartrand
N. Poirier
D. Marleau
Author Affiliation
Québec-Transplant, Montréal, Canada.
Source
Ann Chir. 1991;45(9):791-5
Date
1991
Language
French
Publication Type
Article
Keywords
Heart Transplantation - history
Heart-Lung Transplantation - history
History, 20th Century
Humans
Kidney Transplantation - history
Pancreas Transplantation - history
Quebec
Tissue Donors
Tissue and Organ Procurement - methods
Abstract
In Québec, the first organ transplantations have been realized in 1958. Several kidney transplant programs started at that time. Cardiac, liver, pancreas and lungs programs followed and reached a full development in the eighties when Cyclosporin became available. Today, there are 4 university transplant programs in Québec (McGill, Montréal, Laval and Sherbrooke) with a total of 7 kidney, 4 liver, 4 heart, 2 pancreas and 2 lungs centers. More than 2,900 transplantations have been realized. Since 1970, organ procurement and distribution is organized by a central agency called Québec-Transplant (previously Métro-transplantation). Organ donation is done on a voluntary basis as every where in North America. More than 90% of the organs comes from cadaveric donors and more than 90% of the relatives accept organ donation. 50% of the donors have deceased from head trauma and 50% from cerebral hemorrhage. In 1989, multi-organ harvesting has been realized in 64% of the donors. Despite efforts and progresses, the number of patients awaiting an organ transplant is steadily growing and outlast the number of available organs. It is hoped that maximal utilisation of the donors and growing exchanges at a national and international level will help to solve this crucial problem.
PubMed ID
1781622 View in PubMed
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Focal segmental glomerulosclerosis (FSG) 20 years later. From toddler to grown up.

https://arctichealth.org/en/permalink/ahliterature220718
Source
Clin Nephrol. 1993 Jul;40(1):1-6
Publication Type
Article
Date
Jul-1993
Author
J G Mongeau
P O Robitaille
M J Clermont
A. Merouani
P. Russo
Author Affiliation
Department of Pediatrics and Pathology, Sainte-Justine Hospital, Montréal, Québec, Canada.
Source
Clin Nephrol. 1993 Jul;40(1):1-6
Date
Jul-1993
Language
English
Publication Type
Article
Keywords
Actuarial Analysis
Adult
Female
Follow-Up Studies
Glomerulosclerosis, Focal Segmental - epidemiology - mortality - therapy
Humans
Male
Prognosis
Quebec - epidemiology
Survival Analysis
Time Factors
Treatment Outcome
Abstract
In 1981, we reported the outcome of 25 children with FSG after a follow-up of 10 years. In 1991, all the living patients were reevaluated. Ten patients are now in sustained remission. Four patients still present heavy proteinuria with a normal glomerular filtration rate, four required dialysis and seven patients have died. The renal survival curve has stabilized at 56%. These data show an overall outcome slightly more favourable than we had initially reported in 1981. The difference probably stems from our referral system which enables us to see the patients at an earlier stage of their disease. The percentage of deaths is important. Among the various clinical or histological factors of predictive prognostic value only the degree of interstitial damage has reached statistical significance (p
Notes
Comment In: Clin Nephrol. 1995 Feb;43(2):137-87736679
PubMed ID
8358869 View in PubMed
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Quebec Metro-Transplantation Multicenter Study on delayed graft function in kidney transplantation.

https://arctichealth.org/en/permalink/ahliterature233546
Source
Transplant Proc. 1988 Feb;20(1 Suppl 1):428-31
Publication Type
Article
Date
Feb-1988
Author
J. Corman
M. Moukarzel
R. Guttmann
R. Dandavino
G. St-Louis
M J Clermont
R. Mangel
J G Lachance
Author Affiliation
Metro-Transplantation Montreal-Quebec Royal Victoria Hospital, Canada.
Source
Transplant Proc. 1988 Feb;20(1 Suppl 1):428-31
Date
Feb-1988
Language
English
Publication Type
Article
Keywords
Humans
Kidney - physiopathology
Kidney Function Tests
Kidney Transplantation
Postoperative Complications - epidemiology
Quebec
Retrospective Studies
Risk factors
PubMed ID
3279632 View in PubMed
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