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[15-year experience of moxifloxacin in the treatment of patients with bacterial rhinosinusitis].

https://arctichealth.org/en/permalink/ahliterature266614
Source
Vestn Otorinolaringol. 2015;80(3):75-9
Publication Type
Article
Date
2015
Author
A Y Ovchinnikov
M A Edzhe
N A Miroshnichenko
E M Hon
S A Korostelev
Source
Vestn Otorinolaringol. 2015;80(3):75-9
Date
2015
Language
Russian
Publication Type
Article
Keywords
Acute Disease
Anti-Bacterial Agents - pharmacology
Bacterial Infections - diagnosis - drug therapy - microbiology - physiopathology
Fluoroquinolones - pharmacology
Humans
Rhinitis - diagnosis - drug therapy - microbiology - physiopathology
Russia
Sinusitis - diagnosis - drug therapy - microbiology - physiopathology
Treatment Outcome
Abstract
The article summarizes 15 years of experience of the use of moxifloxacin (Avelox) in Russia in patients with acute bacterial rhinosinusitis. Emphasize its high bactericidal activity against a broad spectrum of microorganisms- from basic agents to the atypical and anaerobic microflora. The results of these studies suggest the continued effectiveness of the dosage of 400 mg a short course (7 days) over 15 years of practical use of the drug, which in its clinical efficacy is superior to amoxicillin/clavulanate, cefuroxime axetil and levofloxacin. The safety profile of moxifloxacin, studied at the population level is not associated with an increased risk of adverse effects in compliance with the dosing regimen, taking into account the indications and contraindications.
PubMed ID
26331163 View in PubMed
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