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Body composition and dietary habits in 80-year-old smoking men without cardiovascular disease.

https://arctichealth.org/en/permalink/ahliterature67858
Source
Aging (Milano). 1991 Sep;3(3):269-77
Publication Type
Article
Date
Sep-1991
Author
S. Elmståhl
G. Järnblad
L. Stavenow
P. Jerntorp
H. Pessah-Rasmussen
H. Galvard
P. Nilsson-Ehle
Author Affiliation
Department of Community Health Sciences, Värnhem Hospital, Malmö, Sweden.
Source
Aging (Milano). 1991 Sep;3(3):269-77
Date
Sep-1991
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Aging
Body Composition
Cardiovascular Diseases - epidemiology
Food Habits
Humans
Male
Questionnaires
Research Support, Non-U.S. Gov't
Smoking
Sweden - epidemiology
Abstract
Eighty-year-old male residents in the community of Malmö were questioned about smoking habits and the occurrence of cardiovascular disease (CVD). Of 1,280 subjects, 122 were selected for further studies and allocated into 4 groups: 1) no CVD, non-smokers; 2) no CVD, smokers; 3) CVD, smokers; and 4) CVD, non-smokers. The smokers had consumed on the average 13 g of tobacco daily for 59 years. Lean body mass (LBM), body fat (BF), % body fat (%BF), and total body water (TBW) were estimated by means of bioelectrical impedance analysis. The mean body weight (BW), LBM, and %BF for all subjects were 74.1 +/- 10.2 kg, 58.0 +/- 6.8 kg, and 21.3 +/- 5.9 kg, respectively. There were no significant differences between all subjects with and without CVD. A lower BW among smokers than in non-smokers was explained by lower BF and %BF in the former. Smokers who had lived predominantly in rural areas had lower BW (6.9 kg) and LBM (5.2 kg) than those from an urban area. A positive correlation was noted between the degree of physical activity and LBM and TBW. Seventeen percent of the smokers exercised regularly. The CVD group had higher plasma cholesterol concentrations than the non-CVD group. Plasma triglycerides showed a positive correlation with BF, %BF and BW, whereas HDL cholesterol was negatively correlated with BF, %BF and BW. It is concluded that smoking is one of several important factors related to body composition, and the penetrance of this factor is still apparent in elderly men.
PubMed ID
1764495 View in PubMed
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Cardiovascular risk groups and mortality in an urban swedish male population: the Malmö Preventive Project.

https://arctichealth.org/en/permalink/ahliterature48290
Source
J Intern Med. 1996 Jun;239(6):489-97
Publication Type
Article
Date
Jun-1996
Author
G. Berglund
K F Eriksson
B. Israelsson
T. Kjellström
F. Lindgärde
I. Mattiasson
J A Nilsson
L. Stavenow
Author Affiliation
Department of Medicine, University Hospital, Lund University, Sweden.
Source
J Intern Med. 1996 Jun;239(6):489-97
Date
Jun-1996
Language
English
Publication Type
Article
Keywords
Adult
Aged
Cardiovascular Diseases - etiology - mortality
Coronary Disease - etiology - mortality - prevention & control
Diabetes Complications
Humans
Hypercholesterolemia - complications
Hypertension - complications
Male
Mass Screening
Middle Aged
Primary Prevention
Risk factors
Smoking - adverse effects
Sweden - epidemiology
Urban health
Abstract
OBJECTIVES. To describe the size, overlap and mortality of four cardiovascular risk groups, in order to give a scientific background for the prevention of cardiovascular disease in a representative urban population. SETTING. Section of Preventive Medicine, Department of Medicine, Malmö University Hospital, Malmö, Sweden. SUBJECTS. Between 1974 and 1984 22444 men born between 1949 and 1921, constituting 75% of the total male population in these age groups, took part in a comprehensive screening examination aimed at detecting risk factors for cardiovascular disease. INTERVENTIONS. Those at high-risk of developing cardiovascular disease were referred to their general practitioner or to special clinics for hypertension, hyperlipidaemia and diabetes. The follow-up, which lasted until the end of 1991, averaged 12.2 years. MAIN OUTCOME MEASURES. Total death (n = 1450) and death from ischaemic heart disease (IHD) (n = 471). RESULTS. Hypertension was found in 13%, hypercholesterolaemia in 19% and diabetes mellitus in 2.6% of the subjects; 49% of the subjects smoked. Multiple risk factors were found in over 17% of the total cohort. Despite the intervention, all-cause mortality during follow-up was increased three-fold in smokers and in men with hypercholesterolaemia, four-fold in hypertensive men and five-fold in men with diabetes, compared to men with no risk factors. The vast majority of deaths (81%) occurred in men who smoked, had hypertension or had high serum cholesterol. Ischaemic heart disease (IHD) was increased five-fold in smokers, seven-fold in men with hypercholesterolaemia, nine-fold in hypertensive men and 12-fold in men with diabetes. Again, the vast majority of IHD deaths (86%) occurred in the first three categories. Combinations of risk factors substantially increased total mortality as well as IHD mortality. CONCLUSIONS. The large proportion (64%) of the population with risk factors for cardiovascular disease and the substantially (5-12-fold) increased IHD mortality in those risk groups, calls for actions aimed at preventing premature IHD deaths. Such action should include measures directed towards the whole population and comprehensive treatment programmes for high-risk individuals, including intervention to stop smoking. The substantial overlap between risk factors calls for one high-risk clinic caring for all risk groups.
PubMed ID
8656142 View in PubMed
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Design, findings and five-year follow-up of preventive medical lipid intervention clinic in Malmö.

https://arctichealth.org/en/permalink/ahliterature55664
Source
Scand J Prim Health Care. 1985 Sep;3(3):177-81
Publication Type
Article
Date
Sep-1985
Author
T. Kjellström
S. Lamme
I. Mattiasson
L. Stavenow
A. Tunestål
E. Trell
L. Larsson
K. Svensson
Source
Scand J Prim Health Care. 1985 Sep;3(3):177-81
Date
Sep-1985
Language
English
Publication Type
Article
Keywords
Cholesterol - blood
Follow-Up Studies
Humans
Hypercholesterolemia - prevention & control
Hyperlipidemia - prevention & control
Male
Middle Aged
Myocardial Infarction - prevention & control
Sweden
Triglycerides - blood
Abstract
In a separate lipid intervention clinic integrated within the framework of a multiphasic preventive medical population program in Malmö, 401 of 2431 screening attenders in a male birth-year cohort born in 1927 and 1928 had elevated values of triglyceride and/or cholesterol. Hypertriglyceridemia was more than three times as frequent as hypercholesterolemia. Of these attenders 20% had normal values at the second control, 5% did not attend the second test and 92 (31.2%) of the remaining were referred to other clinics because of other high risk factors. Thus, 209 (8.6% of the screening attenders) males born in 1927 and 1928 attended the lipid clinic for isolated hyperlipidemia. Disregarding a 5-year drop-out frequency of 13 sections, a significant reduction in the lipids was obtained during the follow-up period in those remaining in treatment. This study demonstrates the feasibility in taking care of hyperlipidemic individuals after a screening detection program. Detection and treatment of hyperlipidemia should of course also be initiated in the individual case in ordinary medical practice.
PubMed ID
4059712 View in PubMed
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Effects of cholesterol and inflammation-sensitive plasma proteins on incidence of myocardial infarction and stroke in men.

https://arctichealth.org/en/permalink/ahliterature53720
Source
Circulation. 2002 Jun 4;105(22):2632-7
Publication Type
Article
Date
Jun-4-2002
Author
G. Engström
P. Lind
B. Hedblad
L. Stavenow
L. Janzon
F. Lindgärde
Author Affiliation
Department of Community Medicine, Malmö University Hospital, Malmö, Sweden. Gunnar.Engstrom@smi.mas.lu.se
Source
Circulation. 2002 Jun 4;105(22):2632-7
Date
Jun-4-2002
Language
English
Publication Type
Article
Keywords
Adult
Biological Markers - blood
Blood Proteins - analysis
Cerebrovascular Accident - blood - epidemiology - immunology
Ceruloplasmin - analysis
Cholesterol - blood
Cohort Studies
Comorbidity
Fibrinogen - analysis
Follow-Up Studies
Haptoglobins - analysis
Humans
Hypercholesterolemia - blood - epidemiology
Incidence
Inflammation - blood - immunology
Male
Middle Aged
Mortality
Myocardial Infarction - blood - epidemiology - immunology
Orosomucoid - analysis
Research Support, Non-U.S. Gov't
Risk factors
Sweden - epidemiology
alpha 1-Antitrypsin - analysis
Abstract
BACKGROUND: Although cholesterol is a major cardiovascular risk factor, its association with stroke remains controversial. This study explored whether the cholesterol-related incidence of stroke and myocardial infarction is modified by plasma markers of inflammation in a large, population-based cohort with a long follow-up. METHODS AND RESULTS: Plasma cholesterol and 5 inflammation-sensitive plasma proteins (ISP) (fibrinogen, alpha1-antitrypsin, haptoglobin, ceruloplasmin, and orosomucoid) were determined in 6063 healthy men, 28 to 61 years of age. The incidence of stroke, cardiac events (fatal and nonfatal), and cardiovascular deaths was compared between groups defined by levels of cholesterol and ISP. Mean follow-up was 18.7 years. High ISP level was defined as 2 to 5 ISP in the top quartile. High cholesterol was associated with higher levels of ISP. Hypercholesterolemia (> or =6.5 mmol/L, 251 mg/dL) was associated with an increased incidence of ischemic stroke and cardiac events and with a reduced incidence of intracerebral hemorrhage. The ISP levels modified these associations. After risk factor adjustment, men with hypercholesterolemia and high ISP levels had a significantly higher risk of cardiovascular death (relative risk [RR]=2.4; CI, 1.8 to 3.3), cardiac events (RR=2.3; CI, 1.8 to 3.0), and ischemic stroke (RR=2.1; CI, 1.4 to 3.3) than men with normal cholesterol and low ISP levels. In the absence of high ISP levels, hypercholesterolemia was associated with a moderately higher risk of cardiovascular death (RR=1.4; CI, 1.0 to 2.0) and cardiac events (RR=1.5; CI, 1.2 to 1.9) but not significantly with ischemic stroke (RR=1.25; CI, 0.8 to 2.0). CONCLUSIONS: Hypercholesterolemia is associated with high plasma levels of ISP. These proteins increase the cholesterol-related incidence of cardiovascular diseases. In the absence of elevated ISP levels, no statistically confirmed association was found between hypercholesterolemia and ischemic stroke.
Notes
Comment In: Circulation. 2002 Jun 4;105(22):2583-512045159
Comment In: Circulation. 2002 Jun 4;105(22):e911112045180
PubMed ID
12045169 View in PubMed
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Eighty-year-old men without cardiovascular disease in the community of Malmö. Part I. Social and medical factors, with special reference to the lipoprotein pattern.

https://arctichealth.org/en/permalink/ahliterature55341
Source
J Intern Med. 1990 Jul;228(1):9-15
Publication Type
Article
Date
Jul-1990
Author
L. Stavenow
S. Elmståhl
P. Jerntorp
P. Nilsson-Ehle
H. Pessah-Rasmussen
H. Galvard
F. Hansen
S M Samuelsson
Author Affiliation
Department of Medicine, Malmö General Hospital, Sweden.
Source
J Intern Med. 1990 Jul;228(1):9-15
Date
Jul-1990
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Alkaline Phosphatase - metabolism
Cardiovascular Diseases - blood - epidemiology
Cholesterol - blood
Creatinine - blood
Cross-Sectional Studies
Hemoglobin A, Glycosylated - analysis
Humans
Hypertension - blood
Lipoproteins - blood
Male
Myocardial Infarction - blood
Prevalence
Research Support, Non-U.S. Gov't
Risk factors
Smoking - adverse effects - blood
Sweden - epidemiology
Vitamin B 12 - blood
Abstract
A total of 1280 80-year-old men were invited to a medical examination to study common risk indicators for cardiovascular disease (CVD) in the elderly. From the pool of 811 responders (63.3%), all 122 individuals who fulfilled our inclusion criteria were assigned to one of four groups: (1) no CVD, non-smokers; (2) no CVD, smokers; (3) CVD, smokers; (4) CVD, non-smokers. A telephone interview with 75 non-responders suggested that this group contained more institutionalized subjects, but otherwise did not differ from the group of participants. Subjects with CVD had higher levels of plasma cholesterol and LDL cholesterol than those without CVD, whereas plasma HDL cholesterol and plasma triglyceride concentrations did not differ between the groups; thus the LDL/HDL ratio was higher in the CVD group. Lipoprotein concentrations did not differ between smokers and non-smokers. However, the mean cholesterol levels were low (5.19 +/- 1.01 mmol l-1), suggesting selective mortality. No differences between the groups were found with regard to Lp(a). The mean blood pressure for the whole group was 149/79 mmHg, and there were no differences between subgroups. Our study suggests that mechanisms such as selective mortality modify the risk factor pattern in the elderly. In 80-year-old individuals, elevated LDL cholesterol levels can still be identified as a risk indicator for CVD, whereas there does not appear to be any association between CVD or low HDL levels or elevated blood pressure in this age group.
PubMed ID
2384740 View in PubMed
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Influence of plasma fibrinogen levels on the incidence of myocardial infarction and death is modified by other inflammation-sensitive proteins: a long-term cohort study.

https://arctichealth.org/en/permalink/ahliterature53966
Source
Arterioscler Thromb Vasc Biol. 2001 Mar;21(3):452-8
Publication Type
Article
Date
Mar-2001
Author
P. Lind
B. Hedblad
L. Stavenow
L. Janzon
K F Eriksson
F. Lindgärde
Author Affiliation
Division of Medical Angiology, Department of Internal Medicine, Division of Epidemiology, Lund University, Malmö University Hospital, Malmö, Sweden. Peter.C.Lind@skane.se
Source
Arterioscler Thromb Vasc Biol. 2001 Mar;21(3):452-8
Date
Mar-2001
Language
English
Publication Type
Article
Keywords
Adult
Cardiovascular Diseases - blood - mortality
Ceruloplasmin - metabolism
Cohort Studies
Fibrinogen - metabolism
Follow-Up Studies
Haptoglobins - metabolism
Humans
Incidence
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction - blood - epidemiology - mortality
Orosomucoid - metabolism
Survival Rate
Sweden - epidemiology
Time Factors
alpha 1-Antitrypsin - metabolism
Abstract
Inflammation may play an important role in atherosclerotic disease. Plasma fibrinogen is an established predictor of cardiovascular events. The aim of this study was to evaluate whether other inflammation-sensitive plasma proteins modify this prediction. We studied the incidence of cardiac events and death in men in relation to fibrinogen levels alone and in combination with other proteins. The study was based on 6075 men, who were, on average, 46 years old at the time of the screening examination, which included the quantitative assessment of plasma levels of fibrinogen, orosomucoid, alpha(1)-antitrypsin, haptoglobin, and ceruloplasmin. The concentration of each protein was divided into quartiles for each. This classification made it possible to identify 4 groups, ie, men in the first fibrinogen quartile and at the same time either not belonging to the fourth quartile of any of the other proteins (Q1/No group) or also belonging to the fourth quartile of >/=1 of the additional proteins (Q1/Yes group) and corresponding groups in the fourth fibrinogen quartile (Q4/No and Q4/Yes groups). During the follow-up, which occurred at an average of 16 years, 439 (7.2%) men experienced a cardiac event, and 653 (10.7%) died; 278 of these men died of cardiovascular diseases, with 206 deaths attributed to ischemic heart disease. From the lowest to the highest quartile, there was for each protein a stepwise increase in the incidence of cardiac events and mortality. All-cause mortality and cardiovascular mortality were significantly higher in the Q4/Yes group compared with the Q4/No group, but they were similar in the Q4/No and Q1/Yes groups. The incidence of cardiac events was significantly higher in the Q1/Yes and Q4/Yes groups compared with the Q1/No and Q4/No groups, respectively. The increased cardiovascular mortality and cardiac event rates remained after adjustment for several confounders when the Q4/Yes and Q4/No groups were compared. The results suggest that the incidence of cardiac events and death due to cardiovascular diseases in middle-aged men predicted by plasma levels of fibrinogen is modified by other inflammation-sensitive proteins.
PubMed ID
11231928 View in PubMed
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Influence of serum triglyceride levels on the risk for myocardial infarction in 12,510 middle aged males: interaction with serum cholesterol.

https://arctichealth.org/en/permalink/ahliterature10579
Source
Atherosclerosis. 1999 Dec;147(2):243-7
Publication Type
Article
Date
Dec-1999
Author
L. Stavenow
T. Kjellström
Author Affiliation
Department of Medicine, Malmö University Hospital, University of Lund, S-205 02, Malmö, Sweden.
Source
Atherosclerosis. 1999 Dec;147(2):243-7
Date
Dec-1999
Language
English
Publication Type
Article
Keywords
Age Distribution
Cholesterol - blood
Humans
Incidence
Logistic Models
Male
Mass Screening
Middle Aged
Myocardial Infarction - blood - epidemiology - etiology
Population Surveillance
Risk assessment
Risk factors
Sensitivity and specificity
Sweden - epidemiology
Triglycerides - blood
Abstract
OBJECTIVE: To study the influence of different levels of serum (s)-triglycerides in relation to s-cholesterol on the risk of myocardial infarction. DESIGN AND SUBJECTS: A 6-13 (mean 10) year follow-up of 12,510 middle-aged men. Fasting s-triglycerides and s-cholesterol were measured at the screening examination. SETTING: Section of Preventive Medicine at the Department of Internal Medicine, Malmö General Hospital, an urban hospital for 240,000 inhabitants in southern Sweden. INTERVENTION: In minor groups of patients there were interventions addressing high lipid levels, high alcohol consumption, hypertension and glucose intolerance. MAIN OUTCOME MEASURE: Myocardial infarction was used as an end-point. RESULTS: 446 myocardial infarctions occurred. The cumulative incidence rates were for the lowest triglyceride quartile 1.2%, for the second 3.2%, for the third 4.1% and for the highest 5.6%. After adjustment for age, year of screening, body mass index, diabetes, smoking, hypertension and s-cholesterol there was a significant relationship between triglycerides and the relative risk for myocardial infarction (P for trend=0.0087). For increasing levels of triglycerides, adjusted for the above factors except cholesterol, the impact of a certain cholesterol value for the occurrence of myocardial infarction was increased (P for trend=0.0092). CONCLUSIONS: The present study emphasizes the interaction between cholesterol and triglyceride values for the risk of myocardial infarction. It is concluded that at triglyceride values above 1.0 mmol/l and cholesterol above 6.8 mmol/l there is an increasing interaction between cholesterol and triglyceride levels that might be of importance when evaluating the cardiovascular risk of middle aged men.
PubMed ID
10559509 View in PubMed
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Long-term effects of inflammation-sensitive plasma proteins and systolic blood pressure on incidence of stroke.

https://arctichealth.org/en/permalink/ahliterature187476
Source
Stroke. 2002 Dec;33(12):2744-9
Publication Type
Article
Date
Dec-2002
Author
G. Engström
P. Lind
B. Hedblad
L. Stavenow
L. Janzon
F. Lindgärde
Author Affiliation
Departments of Community Medicine, Malmö University Hospital, Malmö, Sweden. Gunnar.Engstrom@smi.mas.lu.se
Source
Stroke. 2002 Dec;33(12):2744-9
Date
Dec-2002
Language
English
Publication Type
Article
Keywords
Adult
Blood Pressure - physiology
Blood Proteins - analysis
Ceruloplasmin - analysis
Comorbidity
Diastole
Fibrinogen - analysis
Follow-Up Studies
Haptoglobins - analysis
Humans
Hypertension - blood - mortality
Incidence
Inflammation - blood
Male
Middle Aged
Orosomucoid - analysis
Predictive value of tests
Risk assessment
Risk factors
Stroke - blood - mortality
Sweden - epidemiology
Systole
Time
alpha 1-Antitrypsin - analysis
Abstract
The present study investigated the relationships between inflammation-sensitive plasma proteins (ISPs) and systolic blood pressure (SBP), as well as the joint long-term effects of ISP and SBP on incidence of stroke.
BP and 5 ISPs (fibrinogen, alpha1-antitrypsin, haptoglobin, ceruloplasmin, orosomucoid) were assessed in 6071 healthy men 28 to 61 years of age. All-cause mortality and incidence of stroke were monitored over a mean follow-up of 18.7 years in men defined by SBP (/=140 mm Hg) and ISP (0 to 1 or 2 to 5 ISPs in the top quartile).
SBP and diastolic BP were significantly and positively associated with the number of ISPs in the top quartile. As expected, elevated SBP was associated with an increased incidence of stroke. Among men with SBP >/=140 mm Hg, there were, however, significant differences between those with high and low ISP levels. After risk factor adjustment, men with SBP >/=140 mm Hg and high ISP levels had a relative risk of stroke of 4.3 (95% CI, 2.3 to 7.8) compared with men with SBP /=140 was 2.5 (95% CI,1.4 to 4.6). Men with high ISP levels had a significantly increased risk of stroke also after exclusion of the events from the first 10 years of follow-up.
High ISP levels are associated with elevated BP. These proteins are associated with an increased risk of stroke among men with high BP and provide information on stroke risk even after many years of follow-up.
Notes
Comment In: Stroke. 2003 Apr;34(4):83912663870
Comment In: Stroke. 2002 Dec;33(12):2732-312468759
PubMed ID
12468764 View in PubMed
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Risk of myocardial infarction and stroke in smokers is related to plasma levels of inflammation-sensitive proteins.

https://arctichealth.org/en/permalink/ahliterature53420
Source
Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):577-82
Publication Type
Article
Date
Mar-2004
Author
P. Lind
G. Engström
L. Stavenow
L. Janzon
F. Lindgärde
B. Hedblad
Author Affiliation
Department of Internal Medicine, Malmö University Hospital, S-20502 Malmö, Sweden. Peter.C.Lind@skane.se
Source
Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):577-82
Date
Mar-2004
Language
English
Publication Type
Article
Keywords
Adult
Biological Markers
Carboxyhemoglobin - analysis
Cerebrovascular Accident - blood - epidemiology
Ceruloplasmin - analysis
Cohort Studies
Comorbidity
Comparative Study
Fibrinogen - analysis
Follow-Up Studies
Haptoglobins - analysis
Humans
Inflammation - blood
Male
Middle Aged
Motor Activity
Myocardial Infarction - blood - epidemiology
Orosomucoid - analysis
Prospective Studies
Questionnaires
Research Support, Non-U.S. Gov't
Risk
Smoking - adverse effects - blood - epidemiology
Smoking Cessation
Sweden - epidemiology
alpha 1-Antitrypsin - analysis
Abstract
BACKGROUND: The extent to which differences in cardiovascular risk between smokers with similar daily tobacco consumption may be related to plasma levels of inflammation-sensitive proteins (ISP) and whether these proteins are associated with levels of carboxyhemoglobin (COHb%) have not been clarified. METHODS AND RESULTS: In a population-based cohort of 1489 never smokers, 1685 former smokers, and 2901 current smokers, aged 28 to 61 years, plasma levels of orosomucoid (alpha(1)-acid glycoprotein), alpha(1)-antitrypsin, haptoglobin, fibrinogen, and ceruloplasmin were measured. COHb% levels were available for 2098 of them. Incidence of myocardial infarction, stroke, and death were monitored over 18.7+/-4.7 years. The proportion with high ISP levels (ie, > or =2 ISP in the top quartile) increased progressively with daily tobacco consumption (P
PubMed ID
14726408 View in PubMed
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Selenoprotein P in plasma in relation to cancer morbidity in middle-aged Swedish men.

https://arctichealth.org/en/permalink/ahliterature20471
Source
Nutr Cancer. 2000;36(1):19-26
Publication Type
Article
Date
2000
Author
M E Persson-Moschos
L. Stavenow
B. Akesson
F. Lindgärde
Author Affiliation
Division of Biomedical Nutrition, Lund University, Sweden.
Source
Nutr Cancer. 2000;36(1):19-26
Date
2000
Language
English
Publication Type
Article
Keywords
Blood Glucose - analysis
Body mass index
Case-Control Studies
Cohort Studies
Digestive System Neoplasms - blood
Humans
Male
Middle Aged
Morbidity
Neoplasms - blood - epidemiology
Odds Ratio
Proteins - analysis
Research Support, Non-U.S. Gov't
Respiratory Tract Neoplasms - blood
Risk factors
Selenoprotein P
Selenoproteins
Serum Albumin - analysis
Smoking - blood
Sweden
Urologic Neoplasms - blood
alpha 1-Antitrypsin - analysis
gamma-Glutamyltransferase - blood
Abstract
The premorbid level of selenoprotein P in plasma from subjects with cancer at different sites was compared with that from control subjects in a nested case-control study. A health screening of 12,500 middle-aged men was performed during 1974-1982 in Malmö, Sweden, and from the 400 cancer cases that were identified during follow-up until the end of 1988, 302 plasma samples were available for analysis of selenoprotein P. Two living controls per case of the same screening day and age were chosen. Selenoprotein P levels in subgroups of major cancer sites were lower in cases than in controls for the respiratory tract (1.20 and 1.30 arbitrary units, respectively; p
PubMed ID
10798212 View in PubMed
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10 records – page 1 of 1.