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76 records – page 1 of 8.

Adenocarcinoma of the anal ducts. A series of 21 cases.

https://arctichealth.org/en/permalink/ahliterature25879
Source
Dis Colon Rectum. 1988 Apr;31(4):268-72
Publication Type
Article
Date
Apr-1988
Author
S L Jensen
M H Shokouh-Amiri
K. Hagen
H. Harling
O V Nielsen
Author Affiliation
Department of Surgical Gastroenterology C, Rigshospitalet, University of Copenhagen, Denmark.
Source
Dis Colon Rectum. 1988 Apr;31(4):268-72
Date
Apr-1988
Language
English
Publication Type
Article
Keywords
Adenocarcinoma - diagnosis - mortality - surgery
Adult
Aged
Aged, 80 and over
Anus Neoplasms - diagnosis - mortality - surgery
Denmark
Female
Follow-Up Studies
Humans
Male
Middle Aged
Abstract
The records of 21 patients treated for adenocarcinoma of the anal ducts between 1943 and 1982 were reviewed. The patients were followed until death or current status in April 1987. The median follow-up period was eight months (range, 3 to 144 months). Fifteen patients had an erroneous diagnosis made at first physician visit resulting in a median doctor's delay of 14 months (range, 3 to 24 months) before correct treatment was carried out. Nine of the tumors were localized perianally (ischiorectal space), seven anally, and five in a fistula-in-ano. Tumors localized anally were significantly smaller and had a significantly shorter history than perianally or fistula-in-ano localized tumors (P less than .05 for each localization). Three patients with anal tumors had their diagnosis made accidentally by routine histologic examination of an excised hemorrhoid. First examination revealed distant metastases in 13 patients and follow-up examination revealed regional or distant metastases in seven patients. Modes of treatment were wide local excision (N = 3), abdominoperineal resection (N = 3), colostomy (N = 9), and radiotherapy (N = 2). Twenty of the 21 patients died within 18 months due to the cancer. One long-term survivor was observed; the patient was alive 12 years after local excision of the tumor without evidence of recurrent disease. The crude five- and 10-year survival was only 4.8 percent.
PubMed ID
3359895 View in PubMed
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Alterations in thyroid hormone status in Greenland sledge dogs exposed to whale blubber contaminated with organohalogen compounds.

https://arctichealth.org/en/permalink/ahliterature100348
Source
Ecotoxicol Environ Saf. 2011 Jan;74(1):157-63
Publication Type
Article
Date
Jan-2011
Author
Maja Kirkegaard
Christian Sonne
Rune Dietz
Robert J Letcher
Asger L Jensen
Signe Stige Hansen
Bjørn Munro Jenssen
Philippe Grandjean
Author Affiliation
Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, J.B.Winsløvsvej 17, DK-5000 Odense, Denmark. majakirkegaard@yahoo.dk
Source
Ecotoxicol Environ Saf. 2011 Jan;74(1):157-63
Date
Jan-2011
Language
English
Publication Type
Article
Abstract
As a model of high trophic level carnivores, sledge dogs were fed from 2 to 18 months of age with minke whale blubber containing organohalogen compounds (OHC) corresponding to 128 µg PCB/day. Controls were fed uncontaminated porcine fat. Thyroid hormone levels were assessed in 7 exposed and 7 control sister bitches (sampled at age 6-18 months) and 4 exposed and 4 control pups, fed the same diet as their mothers (sampled age 3-12 months). Lower free and total T3 and T4 were seen in exposed vs. control bitches beyond 10 months of age, and total T3 was lower through 3-12 months of age in exposed pups. A negative correlation with thyroid gland weight was significant for SDDT, as was a positive association with total T3 for dieldrin. This study therefore supports observational data that OHCs may adversely affect thyroid functions, and it suggests that OHC exposure duration of 10 months or more may be required for current OHC contamination levels to result in detectable adverse effects on thyroid hormone dynamics.
PubMed ID
20888641 View in PubMed
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[Anal cancer in Denmark 1943-1973. II. Rare forms of perianal and anal tumors]

https://arctichealth.org/en/permalink/ahliterature27069
Source
Ugeskr Laeger. 1982 Mar 22;144(12):857-60
Publication Type
Article
Date
Mar-22-1982

[Anal cancer in Denmark 1943-1973. I. Planocellular carcinoma of the anus - diagnosis, therapy and prognosis]

https://arctichealth.org/en/permalink/ahliterature27070
Source
Ugeskr Laeger. 1982 Mar 22;144(12):851-6
Publication Type
Article
Date
Mar-22-1982

[Attitude of the population to organ transplantation]

https://arctichealth.org/en/permalink/ahliterature73179
Source
Ugeskr Laeger. 1994 May 9;156(19):2869-72
Publication Type
Article
Date
May-9-1994
Author
S. Keiding
S L Jensen
H. Vilstrup
Author Affiliation
Arhus Kommunehospital, transplantationscentret.
Source
Ugeskr Laeger. 1994 May 9;156(19):2869-72
Date
May-9-1994
Language
Danish
Publication Type
Article
Keywords
Adult
Aged
Denmark
English Abstract
Female
Health Knowledge, Attitudes, Practice
Humans
Male
Middle Aged
Organ Transplantation - psychology
Public Opinion
Questionnaires
Tissue Donors - legislation & jurisprudence - psychology
Tissue and Organ Procurement
Abstract
The attitude of the Danish population towards organ transplantation was examined by means of an interview study, executed by the Gallup Institute. From a sample population of 1391 persons above 18 years of age, 798 persons (70%) were interviewed, in the period April 24th to May 3rd 1992. When asked what they thought the general attitude toward transplantation was amongst the population, 65% answered "positive" or "very positive". The attitudes to three situations, namely to organ donation after the death of a parent, spouse or child was examined subsequently. Amongst those who had an opinion, 75% (72-76%) were positive and 25% (24-27%) were negative. The younger the interviewed person, the more positive the attitude. According to the Danish law the relatives can decide for or against organ donation if the deceased has not expressed her view on organ donation. In view of the general positive attitude of the population it is proposed that we introduce a system where every adult person is asked concerning his/her attitude, e.g. in connection with the yearly income tax form or renewal of the health insurance certificate.
PubMed ID
8009722 View in PubMed
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Basal cell carcinoma of the anus-a clinical study of 34 cases.

https://arctichealth.org/en/permalink/ahliterature27143
Source
Br J Surg. 1981 Dec;68(12):856-7
Publication Type
Article
Date
Dec-1981
Author
O V Nielsen
S L Jensen
Source
Br J Surg. 1981 Dec;68(12):856-7
Date
Dec-1981
Language
English
Publication Type
Article
Keywords
Adult
Aged
Anus Neoplasms - diagnosis - mortality - surgery
Carcinoma, Basal Cell - diagnosis - mortality - surgery
Female
Humans
Male
Middle Aged
Abstract
Thirty-four patients with basal cell carcinoma of the anus were treated in Denmark between 1943 and 1974. The tumours were usually between 1 and 2 cm in diameter and localized to the anal margins. Three tumours had a diameter of 10 cm and extended into the anal canal. In one case the tumour had spread to the regional lymph nodes. Modes of treatment were wide local excision (27 patients), abdominoperineal excision of the rectum (4 patients), colostomy combined with radiotherapy (1 patient) and radiotherapy alone (2 patients). Local recurrence was observed in 8 cases. After retreatment (re-excision: 5 patients), excision of the rectum (1 patient) and radiotherapy (2 patients), no recurrences were observed in the follow-up period ( greater than 5 years). The crude 5-year survival rate was 72.6 per cent. The death rate was not higher than in the normal population of the same age and sex and no death was due to the basal cell carcinoma.
PubMed ID
7317766 View in PubMed
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Canadian polar bear population structure using genome-wide markers.

https://arctichealth.org/en/permalink/ahliterature306244
Source
Ecol Evol. 2020 Apr; 10(8):3706-3714
Publication Type
Journal Article
Date
Apr-2020
Author
Evelyn L Jensen
Christina Tschritter
Peter V C de Groot
Kristen M Hayward
Marsha Branigan
Markus Dyck
Rute B G Clemente-Carvalho
Stephen C Lougheed
Author Affiliation
Department of Biology Queen's University Kingston ON Canada.
Source
Ecol Evol. 2020 Apr; 10(8):3706-3714
Date
Apr-2020
Language
English
Publication Type
Journal Article
Abstract
Predicting the consequences of environmental changes, including human-mediated climate change on species, requires that we quantify range-wide patterns of genetic diversity and identify the ecological, environmental, and historical factors that have contributed to it. Here, we generate baseline data on polar bear population structure across most Canadian subpopulations (n = 358) using 13,488 genome-wide single nucleotide polymorphisms (SNPs) identified with double-digest restriction site-associated DNA sequencing (ddRAD). Our ddRAD dataset showed three genetic clusters in the sampled Canadian range, congruent with previous studies based on microsatellites across the same regions; however, due to a lack of sampling in Norwegian Bay, we were unable to confirm the existence of a unique cluster in that subpopulation. These data on the genetic structure of polar bears using SNPs provide a detailed baseline against which future shifts in population structure can be assessed, and opportunities to develop new noninvasive tools for monitoring polar bears across their range.
PubMed ID
32313629 View in PubMed
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The Canadian prehospital evidence-based protocols project: knowledge translation in emergency medical services care.

https://arctichealth.org/en/permalink/ahliterature149040
Source
Acad Emerg Med. 2009 Jul;16(7):668-73
Publication Type
Article
Date
Jul-2009
Author
Jan L Jensen
David A Petrie
Andrew H Travers
Author Affiliation
Division of Emergency Medical Services, Dalhousie University, Emergency Health Services, Halifax, Nova Scotia, Canada. jljensen@dal.ca
Source
Acad Emerg Med. 2009 Jul;16(7):668-73
Date
Jul-2009
Language
English
Publication Type
Article
Keywords
Canada
Diffusion of Innovation
Emergency Medical Services - standards - trends
Evidence-Based Medicine
Health Knowledge, Attitudes, Practice
Humans
Information Dissemination
Nova Scotia
Organizational Innovation
Organizational Objectives
Abstract
The principles of evidence-based medicine are applicable to all areas and professionals in health care. The care provided by paramedics in the prehospital setting is no exception. The Prehospital Evidence-based Protocols Project Online (PEP) is a repository of appraised research evidence that is applicable to interventions performed in the prehospital setting and is openly available online. This article describes the history, current status, and potential future of the project.
The primary objective of the PEP is to catalog and grade emergency medical services (EMS) studies with a level of evidence (LOE). Subsequently, each prehospital intervention is assigned a class of recommendation (COR) based on all the appraised articles on that intervention, in an effort to organize the evidence so it may be put into practice efficiently. An LOE is assigned to each article by the section editor, based on the study rigor and applicability to EMS. The section editor committee consists of EMS physicians and paramedics from across Canada, and two from Ireland and a paramedic coordinator. The evidence evaluation cycle is continuous; as the section editors send back appraisals, the coordinator updates the database and sends out another article for review.
The database currently has 182 individual interventions organized under 103 protocols, with 933 citations.
This project directly meets recent recommendations to improve EMS by using evidence to support interventions and incorporating it into protocols. Organizing and grading the evidence allows medical directors and paramedics to incorporate research findings into their daily practice. As such, this project demonstrates how knowledge translation can be conducted in EMS.
PubMed ID
19691810 View in PubMed
Less detail

Can the endometrial thickness as measured by trans-vaginal sonography be used to exclude polyps or hyperplasia in pre-menopausal patients with abnormal uterine bleeding?

https://arctichealth.org/en/permalink/ahliterature19698
Source
Acta Obstet Gynecol Scand. 2001 Jul;80(7):645-51
Publication Type
Article
Date
Jul-2001
Author
M. Dueholm
M L Jensen
H. Laursen
P. Kracht
Author Affiliation
Department of Obstetrics and Gynaecology, Department of Pathology, Aarhus University Hospital, Aarhus, Denmark. hjorth@dadlnet.dk
Source
Acta Obstet Gynecol Scand. 2001 Jul;80(7):645-51
Date
Jul-2001
Language
English
Publication Type
Article
Keywords
Adult
Comparative Study
Endometrial Hyperplasia - complications - ultrasonography
Endometrial Neoplasms - complications - pathology - ultrasonography
Endometrium - pathology - ultrasonography
Female
Humans
Hysterectomy
Hysteroscopy
Middle Aged
Polyps - complications - ultrasonography
Prospective Studies
ROC Curve
Statistics, nonparametric
Uterine Hemorrhage - etiology - pathology - ultrasonography
Abstract
BACKGROUND: To combine findings of normal mid-line echoes from TVS (trans-vaginal sonography) with cut-off levels for endometrial thickness, in order to examine the associated risk of abnormalities in the uterine cavity. DESIGN AND SETTING: Two center prospective study at a university clinic and a central hospital in Denmark. PARTICIPANTS: Three hundred and fifty-five pre-menopausal patients with abnormal uterine bleeding, and indications for endometrial sampling or surgery. INTERVENTIONS: The thickness of the endometrium was measured, and the mid-line echoes were evaluated using TVS. The findings from the endometrial sampling, combined with the evaluation of the uterine cavity using operative hysteroscopy (115), hysterectomy (74) or HSE (hysterosonographic examination) (166), were used as the true values. RESULTS: The mean (+/-s.d.) endometrial thickness was significantly different in patients with hyperplasia 11.5 mm (+/-5.0), polyps 11.8 mm (+/-5.1), sub-mucous myomas 7.1 mm (+/-3.4) and in patients without these abnormalities 8.37 (+/-3.9) (p
PubMed ID
11437723 View in PubMed
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76 records – page 1 of 8.