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Coxiella burnetii exposure in northern sea otters Enhydra lutris kenyoni.

https://arctichealth.org/en/permalink/ahliterature267029
Source
Dis Aquat Organ. 2015 May 11;114(1):83-7
Publication Type
Article
Date
May-11-2015
Author
Colleen Duncan
Verena A Gill
Kristin Worman
Kathy Burek-Huntington
Kristy L Pabilonia
Sam Johnson
Kelly A Fitzpatrick
Christina Weller
Gilbert J Kersh
Source
Dis Aquat Organ. 2015 May 11;114(1):83-7
Date
May-11-2015
Language
English
Publication Type
Article
Keywords
Alaska - epidemiology
Animals
Coxiella burnetii
Endocarditis, Bacterial - epidemiology - microbiology - veterinary
Female
Male
Otters
Q Fever - epidemiology - veterinary
Seroepidemiologic Studies
Abstract
Valvular endocarditis has been well described in northern sea otters Enhydra lutris kenyoni of Alaska and in many cases no cause has been identified. It is also one of the most common conditions observed in people with chronic Coxiella burnetii infection. Given the high levels of C. burnetii exposure in marine mammals distributed throughout the same geographic range as the northern sea otter, and the presence of valvular lesions seen in otters, the objective of this study was to determine the level of C. burnetii exposure in otters and investigate any association between exposure, infection and valvular disease in this species. Archived serum from 75 live captured, apparently healthy otters (25 from each of 3 stocks) and 30 dead otters were tested for C. burnetii antibodies by indirect florescent antibody assay (IFA). Archived bone marrow and heart valves were tested for C. burnetii DNA by real-time PCR (qPCR). Overall, the seroprevalence in live otters was 17%, with significantly more exposed animals in the south central (40%) stock relative to the southwest (8%) and southeast (4%). The seroprevalence of animals sampled post mortem was 27%, although none of the bone marrow or heart valve samples were positive by qPCR. Results of this study failed to demonstrate a significant association between C. burnetii infection and valvular endocarditis in sea otters; however, the differing seroprevalence suggests that exposure opportunities vary geographically.
PubMed ID
25958809 View in PubMed
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