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Alcohol and coronary heart disease risk--is there an unknown confounder?

https://arctichealth.org/en/permalink/ahliterature173661
Source
Addiction. 2005 Aug;100(8):1150-7
Publication Type
Article
Date
Aug-2005
Author
Kari Poikolainen
Jussi Vahtera
Marianna Virtanen
Anne Linna
Mika Kivimäki
Author Affiliation
Finnish Foundation for Alcohol Studies, Helsinki, Finland. kari.poikolainen@stakes.fi
Source
Addiction. 2005 Aug;100(8):1150-7
Date
Aug-2005
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Alcohol Drinking - adverse effects - epidemiology
Confounding Factors (Epidemiology)
Coronary Disease - epidemiology
Cross-Sectional Studies
Female
Finland - epidemiology
Humans
Life Style
Male
Middle Aged
Regression Analysis
Risk factors
Abstract
To evaluate whether confounding by several known or suspected coronary heart disease risk factors are likely to explain the lower coronary heart disease risk among light alcohol drinkers compared with never-drinkers.
A population-based cross-sectional study.
Hypertension, body mass index (BMI), diabetes, depression, sleep disturbances, smoking, physical activity, life satisfaction, psychological distress, trait anxiety, independent and dependent life events, length of working hours, job control, job strain and effort-reward imbalance were compared between never-drinkers and light drinkers (
PubMed ID
16042645 View in PubMed
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Alcohol intake and sickness absence: a curvilinear relation.

https://arctichealth.org/en/permalink/ahliterature187885
Source
Am J Epidemiol. 2002 Nov 15;156(10):969-76
Publication Type
Article
Date
Nov-15-2002
Author
Jussi Vahtera
Kari Poikolainen
Mika Kivimäki
Leena Ala-Mursula
Jaana Pentti
Author Affiliation
Finnish Institute of Occupational Health, Turku, Finland. jussi.vahtera@ttl.fi
Source
Am J Epidemiol. 2002 Nov 15;156(10):969-76
Date
Nov-15-2002
Language
English
Publication Type
Article
Keywords
Absenteeism
Adult
Alcohol Drinking - adverse effects - epidemiology
Analysis of Variance
Confounding Factors (Epidemiology)
Coronary Disease - epidemiology - etiology
Female
Finland - epidemiology
Health Behavior
Humans
Logistic Models
Male
Middle Aged
Mortality
Population Surveillance
Questionnaires
Risk factors
Social Support
Stress, Psychological - complications - prevention & control - psychology
Abstract
Little is known about the U-shaped relation between alcohol intake and health beyond findings related to cardiovascular disease. Medically certified sickness absence is a health indicator in which coronary heart disease is only a minor factor. To investigate the relation between alcohol intake and sickness absence, records regarding medically certified sick leaves from all causes were assessed for 4 years (1997-2000) in a cohort of 1,490 male and 4,952 female municipal employees in Finland. Hierarchical Poisson regression, adjusted for self-reported behavioral and biologic risk factors, psychosocial risk factors, and cardiovascular diseases, was used to estimate the rate ratios and their 95% confidence intervals, relating sickness absence to each level of alcohol consumption. For both men and women, a significant curvilinear trend was found between level of average weekly alcohol consumption and sickness absence. The rates of medically certified sickness absence were 1.2-fold higher (95% confidence interval: 1.1, 1.3) for never, former, and heavy drinkers compared with light drinkers. The U-shaped relation between alcohol intake and health is not likely to be explained by confounding due to psychosocial differences or inclusion of former drinkers in the nondrinkers category. Moderate alcohol consumption also may reduce health problems other than cardiovascular disease.
PubMed ID
12419770 View in PubMed
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Allergic rhinitis alone or with asthma is associated with an increased risk of sickness absences.

https://arctichealth.org/en/permalink/ahliterature142913
Source
Respir Med. 2010 Nov;104(11):1654-8
Publication Type
Article
Date
Nov-2010
Author
Paula Kauppi
Paula Salo
Riina Hakola
Jaana Pentti
Tuula Oksanen
Mika Kivimäki
Jussi Vahtera
Tari Haahtela
Author Affiliation
Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland. paula.kauppi@hus.fi
Source
Respir Med. 2010 Nov;104(11):1654-8
Date
Nov-2010
Language
English
Publication Type
Article
Keywords
Adult
Aged
Asthma - economics - epidemiology
Female
Finland - epidemiology
Humans
Male
Middle Aged
Occupational Health
Prevalence
Prospective Studies
Public Sector - statistics & numerical data
Rhinitis, Allergic, Perennial - economics - epidemiology
Risk factors
Sick Leave - economics - statistics & numerical data
Young Adult
Abstract
The aim of the study is to examine the risk of sickness absence in public sector employees with allergic rhinitis or asthma or both conditions combined. This is a prospective cohort study of 48,296 Finnish public sector employees. Data from self-reported rhinitis and asthma were obtained from survey responses given during either the 2000-2002 or 2004 periods. Follow-up data on sickness absences for the public sector employees surveyed were acquired from records kept by the employers. During the follow-up, mean sick leave days per year for respondents were 17.6 days for rhinitis alone, 23.8 days for asthma alone and 24.2 days for both conditions combined. Respondents with neither condition were absent for a mean of 14.5 days annually. The impact of asthma and rhinitis combined on the risk of sick leave days was marginal compared to asthma alone (RR 1.1; 95% CI 1.0-1.3). In the subgroup analysis (those with current asthma or allergy medication), the risk ratio for medically certified sickness absence (>3 days) was 2.0 (95% CI 1.9-2.2) for those with asthma and rhinitis combined. Rhinitis, asthma and both these conditions combined increased the risk of days off work.
PubMed ID
20542677 View in PubMed
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Allocation of rehabilitation measures provided by the Social Insurance Institution in Finland: a register linkage study.

https://arctichealth.org/en/permalink/ahliterature163871
Source
J Rehabil Med. 2007 Apr;39(3):198-204
Publication Type
Article
Date
Apr-2007
Author
Heikki Suoyrjö
Katariina Hinkka
Mika Kivimäki
Timo Klaukka
Jaana Pentti
Jussi Vahtera
Author Affiliation
Petrea, Social Insurance Institution of Finland, Turku. heikki.suoyrjo@petrea.fi
Source
J Rehabil Med. 2007 Apr;39(3):198-204
Date
Apr-2007
Language
English
Publication Type
Article
Keywords
Adult
Chronic Disease - rehabilitation
Disability Evaluation
Disabled Persons - rehabilitation
Female
Finland - epidemiology
Humans
Insurance, Health - economics - statistics & numerical data
Male
Middle Aged
Registries
Rehabilitation, Vocational - economics - statistics & numerical data
Retirement - economics - statistics & numerical data
Sick Leave - economics - statistics & numerical data
Social Security - economics - statistics & numerical data
Abstract
To study the allocation of rehabilitation measures provided by the Finnish Social Insurance Institution in relation to the characteristics and health status of rehabilitants.
A register linkage study.
A total of 67,106 full-time local government employees with a minimum of 10-month job contracts in 10 Finnish towns during the period 1994-2002.
Data on the rehabilitation granted between 1994 and 2002, special medication reimbursements for chronic diseases, and disability retirement, were derived from the registers of the Social Insurance Institution as an indicator of chronic morbidity and linked to the employers' records on demographic characteristics and rates of sickness absence.
In comparison with non-rehabilitants, the rate of sickness absence (> 21 days) was 2.2-2.9-fold (95% confidence interval (CI) 2.0-3.0) higher, the odds ratios of special medication reimbursement 1.5-6.1-fold (95% CI 1.3-6.9) higher and disability retirement 3.1-7.5-fold (95% CI 2.7-9.3) higher among rehabilitants. Older women and employees in manual or lower-grade non-manual jobs predominated in the rehabilitation groups. The proportion of temporary employees receiving rehabilitation was low.
Permanently employed older women with an excess burden of health problems predominate in the receipt of rehabilitation provided by the Social Insurance Institution.
PubMed ID
17468787 View in PubMed
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Antidepressant use before and after the diagnosis of type 2 diabetes: a longitudinal modeling study.

https://arctichealth.org/en/permalink/ahliterature144431
Source
Diabetes Care. 2010 Jul;33(7):1471-6
Publication Type
Article
Date
Jul-2010
Author
Mika Kivimäki
Adam G Tabák
Debbie A Lawlor
G David Batty
Archana Singh-Manoux
Markus Jokela
Marianna Virtanen
Paula Salo
Tuula Oksanen
Jaana Pentti
Daniel R Witte
Jussi Vahtera
Author Affiliation
Department of Epidemiology and Public Health, University College London, London, UK. m.kivimaki@ucl.ac.uk
Source
Diabetes Care. 2010 Jul;33(7):1471-6
Date
Jul-2010
Language
English
Publication Type
Article
Keywords
Adult
Antidepressive Agents - therapeutic use
Depressive Disorder - drug therapy - epidemiology
Diabetes Mellitus, Type 2 - epidemiology - psychology
Female
Finland - epidemiology
Humans
Longitudinal Studies
Male
Middle Aged
Neoplasms - epidemiology - psychology
Odds Ratio
Risk factors
Abstract
To examine antidepressant use before and after the diagnosis of diabetes.
This study was a longitudinal analysis of diabetic and nondiabetic groups selected from a prospective cohort study of 151,618 men and women in Finland (the Finnish Public Sector Study, 1995-2005). We analyzed the use of antidepressants in those 493 individuals who developed type 2 diabetes and their 2,450 matched nondiabetic control subjects for each year during a period covering 4 years before and 4 years after the diagnosis. For comparison, we undertook a corresponding analysis on 748 individuals who developed cancer and their 3,730 matched control subjects.
In multilevel longitudinal models, the odds ratio for antidepressant use in those who developed diabetes was 2.00 (95% CI 1.57-2.55) times greater than that in nondiabetic subjects. The relative difference in antidepressant use between these groups was similar before and after the diabetes diagnosis except for a temporary peak in antidepressant use at the year of the diagnosis (OR 2.66 [95% CI 1.94-3.65]). In incident cancer case subjects, antidepressant use substantially increased after the cancer diagnosis, demonstrating that our analysis was sensitive for detecting long-term changes in antidepressant trajectories when they existed.
Awareness of the diagnosis of type 2 diabetes may temporarily increase the risk of depressive symptoms. Further research is needed to determine whether more prevalent use of antidepressants noted before the diagnosis of diabetes relates to effects of depression, side effects of antidepressant use, or a common causal pathway for depression and diabetes.
Notes
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Cites: Diabetes Care. 2008 Jan;31 Suppl 1:S12-5418165335
Cites: Biol Psychiatry. 2007 Dec 1;62(11):1265-7117692292
Cites: Int Clin Psychopharmacol. 2007 Nov;22(6):382-617917558
Cites: Diabetes Care. 2007 Sep;30(9):2216-2117563339
Cites: Diabetologia. 2006 May;49(5):837-4516520921
Cites: Diabetes Care. 2004 Dec;27(12):2856-6215562197
Cites: Psychosom Med. 1997 May-Jun;59(3):241-509178335
Cites: J Psychopharmacol. 2008 Sep;22(7):792-80418308785
Cites: Diabetes Care. 2008 Mar;31(3):420-618071002
Cites: Curr Diabetes Rev. 2007 Nov;3(4):252-918220683
Cites: Psychosom Med. 2001 Jul-Aug;63(4):619-3011485116
Cites: J Clin Psychiatry. 2003;64 Suppl 8:22-912892538
Cites: Diabetes Care. 2004 Feb;27(2):429-3514747224
Cites: Arch Intern Med. 2004 May 10;164(9):1010-415136311
Cites: JAMA. 1983 Feb 11;249(6):751-76823028
Cites: Diabetes Care. 2000 Jul;23(7):934-4210895843
Cites: Diabetes Care. 2001 Jun;24(6):1069-7811375373
Cites: Am J Psychiatry. 2010 May;167(5):580-820123914
Cites: Diabetes Care. 2010 Feb;33(2):298-30319918011
Cites: Diabetes Care. 2009 Oct;32(10):1867-919592627
Cites: Chest. 2009 Jul;136(1):130-619318680
Cites: JAMA. 2008 Jun 18;299(23):2751-918560002
PubMed ID
20368411 View in PubMed
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Are patient-related pre-operative factors influencing return to work after total knee arthroplasty.

https://arctichealth.org/en/permalink/ahliterature310514
Source
Knee. 2019 Aug; 26(4):853-860
Publication Type
Journal Article
Date
Aug-2019
Author
Petteri Lankinen
Raul Laasik
Mika Kivimäki
Ville Aalto
Mikhail Saltychev
Jussi Vahtera
Keijo Mäkelä
Author Affiliation
Department of Orthopedics and Traumatology Turku, Turku University Hospital and University of Turku, Turku, Finland. Electronic address: petteri.lankinen@tyks.fi.
Source
Knee. 2019 Aug; 26(4):853-860
Date
Aug-2019
Language
English
Publication Type
Journal Article
Keywords
Arthroplasty, Replacement, Knee
Female
Finland
Humans
Male
Middle Aged
Multivariate Analysis
Occupations
Osteoarthritis, Knee - surgery
Return to Work - statistics & numerical data
Sick Leave - statistics & numerical data
Abstract
Osteoarthritis is one of the leading causes of disability in working-age patients. The total number of working-age patients undergoing total-knee arthroplasty (TKA) is continuously increasing. The purpose of this study was to identify predictive factors related to general health, health risk behaviors and socioeconomic status influencing the rate of return to work after a TKA.
Overall there were 151,901 patients included in the Finnish Public Sector (FPS) study. The response rate varied between 65 and 73% during the study period. We used Cox proportional hazard models to examine patient-related predictive factors that may influence the rate of return to work after TKA in a cohort of patients (n?=?452; n?=?362 female; mean age 56.4?years). Predictive factors were measured on average 3.6?years before the operation.
Of the patients, 87% returned to work within one year after TKA at a mean of 116 calendar days. In multivariate analysis, patients at sick-leave =30?days during the last year before surgery were 2.2 times (95% confidence interval 1.72-2.92) more likely to return to work compared with those with >30?days of sick-leave. Compared with patients in manual work, those in higher or lower level non-manual work showed a 2.6-fold (1.95-3.52) and 1.5-fold (1.15-1.92) increased probability of returning to work. Age, sex, health risk behaviors, obesity, physical comorbidities, common mental disorders, and other studied health-related factors were not associated with the rate of return to work.
Non-manual job, good self-rated general health and preoperative sick leave =30?days are associated with a higher rate of return to work.
PubMed ID
31126842 View in PubMed
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Association between adverse childhood experiences and adult diseases in older adults: a comparative cross-sectional study in Japan and Finland.

https://arctichealth.org/en/permalink/ahliterature309287
Source
BMJ Open. 2019 08 24; 9(8):e024609
Publication Type
Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Date
08-24-2019
Author
Airi Amemiya
Takeo Fujiwara
Kokoro Shirai
Katsunori Kondo
Tuula Oksanen
Jaana Pentti
Jussi Vahtera
Author Affiliation
Department of Health Economics and Epidemiology Research, University of Tokyo School of Public Health, Bunkyo-ku, Japan.
Source
BMJ Open. 2019 08 24; 9(8):e024609
Date
08-24-2019
Language
English
Publication Type
Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Keywords
Adverse Childhood Experiences - statistics & numerical data
Aged
Child
Cross-Sectional Studies
Female
Finland - epidemiology
Health Behavior
Humans
Japan - epidemiology
Male
Middle Aged
Prevalence
Risk Assessment - methods
Risk factors
Abstract
We aimed to examine the association between adverse childhood experiences (ACEs) and diseases in older adults in Japan and Finland.
Cross-sectional comparative study.
Data from a gerontological study in Japan and two public health studies in Finland were evaluated.
A total of 13?123 adults (mean age, 69.5 years) from Japan and 10?353 adults (mean age, 64.4 years) from Finland were included in this study. Logistic regression was used to examine the association of each of, any of and the cumulative number of ACEs (parental divorce, fear of a family member and poverty in childhood; treated as ordered categorical variables) with poor self-rated health (SRH), cancer, heart disease or stroke, diabetes mellitus, smoking and body mass index. Models were adjusted for sex, age, education, marital status and working status.
Of the respondents, 50% of those in Japan and 37% of those in Finland reported having experienced at least one of the measured ACEs. Number of ACEs was associated with poor SRH in both countries, and the point estimates were similar (OR: 1.35, 95% CI: 1.25 to 1.46 in Japan; OR: 1.34, 95%?CI: 1.27 to 1.41 in Finland). Number of ACEs was associated with the prevalence of cancer, heart disease or stroke, diabetes mellitus, current smoking and an increase in body mass index in both countries.
The association between ACEs and poor SRH, adult diseases and health behaviours was similar among older adults in both Japan and Finland. This international comparative study suggests that the impact of ACEs on health is noteworthy and consistent across cultural and social environments.
PubMed ID
31446402 View in PubMed
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Association Between Distance From Home to Tobacco Outlet and Smoking Cessation and Relapse.

https://arctichealth.org/en/permalink/ahliterature282305
Source
JAMA Intern Med. 2016 Oct 01;176(10):1512-1519
Publication Type
Article
Date
Oct-01-2016
Author
Anna Pulakka
Jaana I Halonen
Ichiro Kawachi
Jaana Pentti
Sari Stenholm
Markus Jokela
Ilkka Kaate
Markku Koskenvuo
Jussi Vahtera
Mika Kivimäki
Source
JAMA Intern Med. 2016 Oct 01;176(10):1512-1519
Date
Oct-01-2016
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Cohort Studies
Commerce
Female
Finland - epidemiology
Humans
Logistic Models
Male
Middle Aged
Smoking - epidemiology
Smoking Cessation - statistics & numerical data
Surveys and Questionnaires
Tobacco Products
Walking
Young Adult
Abstract
Reduced availability of tobacco outlets is hypothesized to reduce smoking, but longitudinal evidence on this issue is scarce.
To examine whether changes in distance from home to tobacco outlet are associated with changes in smoking behaviors.
The data from 2 prospective cohort studies included geocoded residential addresses, addresses of tobacco outlets, and responses to smoking surveys in 2008 and 2012 (the Finnish Public Sector [FPS] study, n?=?53?755) or 2003 and 2012 (the Health and Social Support [HeSSup] study, n?=?11?924). All participants were smokers or ex-smokers at baseline. We used logistic regression in between-individual analyses and conditional logistic regression in case-crossover design analyses to examine change in walking distance from home to the nearest tobacco outlet as a predictor of quitting smoking in smokers and smoking relapse in ex-smokers. Study-specific estimates were pooled using fixed-effect meta-analysis.
Walking distance from home to the nearest tobacco outlet.
Quitting smoking and smoking relapse as indicated by self-reported current and previous smoking at baseline and follow-up.
Overall, 20?729 men and women (age range 18-75 years) were recruited. Of the 6259 and 2090 baseline current smokers, 1744 (28%) and 818 (39%) quit, and of the 8959 and 3421 baseline ex-smokers, 617 (7%) and 205 (6%) relapsed in the FPS and HeSSup studies, respectively. Among the baseline smokers, a 500-m increase in distance from home to the nearest tobacco outlet was associated with a 16% increase in odds of quitting smoking in the between-individual analysis (pooled odds ratio, 1.16; 95% CI, 1.05-1.28) and 57% increase in within-individual analysis (pooled odds ratio, 1.57; 95% CI, 1.32-1.86), after adjusting for changes in self-reported marital and working status, substantial worsening of financial situation, illness in the family, and own health status. Increase in distance to the nearest tobacco outlet was not associated with smoking relapse among the ex-smokers.
These data suggest that increase in distance from home to the nearest tobacco outlet may increase quitting among smokers. No effect of change in distance on relapse in ex-smokers was observed.
PubMed ID
27533777 View in PubMed
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Association between education and television viewing among older working and retired people: a comparative study of Finland and Japan.

https://arctichealth.org/en/permalink/ahliterature303182
Source
BMC Public Health. 2018 07 25; 18(1):917
Publication Type
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Date
07-25-2018
Author
Taishi Tsuji
Airi Amemiya
Kokoro Shirai
Sari Stenholm
Jaana Pentti
Tuula Oksanen
Jussi Vahtera
Katsunori Kondo
Author Affiliation
Center for Preventive Medical Sciences, Chiba University, 1-8-1 Inohana, Chuo Ward, Chiba City, Chiba, Japan. tsuji.t@chiba-u.jp.
Source
BMC Public Health. 2018 07 25; 18(1):917
Date
07-25-2018
Language
English
Publication Type
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Aged
Body mass index
Cohort Studies
Cross-Sectional Studies
Educational Status
Employment - psychology - statistics & numerical data
Exercise
Female
Finland - epidemiology
Humans
Japan - epidemiology
Male
Prevalence
Recreation - psychology
Retirement - psychology - statistics & numerical data
Sedentary Behavior
Smoking
Television - statistics & numerical data
Abstract
Educational attainment is associated with physical activity among older people. However, little is known about its association with sedentary lifestyle in European as well as Asian nations. This study aims to examine the associations between educational attainment and daily television viewing as an indicator of a sedentary lifestyle among older working and retired people in Finland and Japan.
We used cross-sectional harmonized data from two cohorts, the Finnish Public Sector study (n?=?10,744) and the Japan Gerontological Evaluation Study (n?=?2493), evaluating individuals aged 65-75 years old. We defined high-duration television viewing as =4 h per day. Poisson regression was used to examine the association between educational attainment and high-duration television viewing, stratified by the current working status. Models were adjusted for age, sex, household size, smoking, alcohol, body mass index, chronic diseases, mental disorders, and physical activity.
Of the participants, 27% in Finland and 30% in Japan reported high-duration television viewing. Compared with a low education (=9 years), Finnish and Japanese retirees with a high education (=13 years) had less high-duration television viewing [prevalence ratio, PR 0.68 (95% confidence interval 0.63-0.73) and 0.66 (0.55-0.79), respectively]. The corresponding PRs for Finnish and Japanese retirees with intermediate education were also lowered [0.89 (0.83-0.95) and 0.79 (0.68-0.91), respectively]. Among older people still at work, educational attainment was associated with high-duration television viewing among the Japanese but not among the Finnish.
A similar association between educational attainment and high-duration television viewing in Finland and Japan particularly after retirement suggests a robust and consistent impact of educational attainment on a sedentary lifestyle after retirements.
PubMed ID
30045698 View in PubMed
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Association between exposure to work stressors and cognitive performance.

https://arctichealth.org/en/permalink/ahliterature258897
Source
J Occup Environ Med. 2014 Apr;56(4):354-60
Publication Type
Article
Date
Apr-2014
Author
Marko Vuori
Ritva Akila
Virpi Kalakoski
Jaana Pentti
Mika Kivimäki
Jussi Vahtera
Mikko Härmä
Sampsa Puttonen
Source
J Occup Environ Med. 2014 Apr;56(4):354-60
Date
Apr-2014
Language
English
Publication Type
Article
Keywords
Adult
Cognition Disorders - epidemiology - psychology
Female
Finland - epidemiology
Hospitals
Humans
Middle Aged
Personnel, Hospital - psychology
Questionnaires
Stress, Psychological - psychology
Abstract
To examine the association between work stress and cognitive performance.
Cognitive performance of a total of 99 women (mean age = 47.3 years) working in hospital wards at either the top or bottom quartiles of job strain was assessed using validated tests that measured learning, short-term memory, and speed of memory retrieval.
The high job strain group (n = 43) had lower performance than the low job strain group (n = 56) in learning (P = 0.025), short-term memory (P = 0.027), and speed of memory retrieval (P = 0.003). After controlling for education level, only the difference in speed of memory retrieval remained statistically significant (P = 0.010).
The association found between job strain and speed of memory retrieval might be one important factor explaining the effect of stress on work performance.
PubMed ID
24709760 View in PubMed
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231 records – page 1 of 24.