The authors analyze the development histories of 54 full-term newborns born in a satisfactory state, though in need of intensive care and rehabilitation at a special department for neonatal diseases. The absence of asphyxia at birth could not preclude a disease in the future. Analysis of mother's risk factors and neonatal disease permit a conclusion that babies born to mothers with a high-risk pregnancy even when born full-term should be singled out as a special group because of a high risk of disease development (intrauterine infection, cerebral disturbances, developmental defects, endocrine diseases, metabolic disorders, etc.). The most significant of mother's risk factors are reproductive function abnormalities (sterility, habitual abortions, a history of perinatal loss, etc.). Analysis of erroneous policy of neonatologists and late treatment start demonstrated that maternal risk factors should be more thoroughly assessed at childbirth.