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Cancer incidence among male Norwegian asphalt workers.

https://arctichealth.org/en/permalink/ahliterature18719
Source
Am J Ind Med. 2003 Jan;43(1):88-95
Publication Type
Article
Date
Jan-2003
Author
Britt Grethe Randem
Sverre Langård
Inge Dale
Johny Kongerud
Jan Ivar Martinsen
Aage Andersen
Author Affiliation
Rikshospitalet University Hospital, Centre for Occupational and Environmental Medicine, Oslo, Norway. britt.randem@rikshospitalet.no
Source
Am J Ind Med. 2003 Jan;43(1):88-95
Date
Jan-2003
Language
English
Publication Type
Article
Keywords
Cohort Studies
Humans
Hydrocarbons
Incidence
Inhalation Exposure
Lung Neoplasms - epidemiology
Male
Melanoma - epidemiology
Neoplasms - epidemiology
Norway - epidemiology
Occupational Diseases - epidemiology
Occupational Exposure
Research Support, Non-U.S. Gov't
Abstract
BACKGROUND: The main objective of the present study was to investigate whether exposure to bitumen fumes could enhance the risk of cancer in asphalt workers. METHODS: A historical prospective cohort study was performed including 8,763 male asphalt workers from all main asphalt companies in Norway. Name, date of birth, and unique personal identification number, address, job type, and start and stop of employment in specific jobs was obtained for the workers. Information was complied from payroll and personnel records in the companies. The cohort was then linked to the Cancer Registry of Norway, which has complete records of individual cases of cancer in the Norwegian population since 1953. Follow-up was from 1 January 1970 to 31 December 1997. The 5-year age and period adjusted general male population in Norway served as reference population. RESULTS: Lung cancer was found elevated with standardized incidence ratio (SIR) = 1.3 (95% confidence intervals (CI) = 1.1, 1.7) in the overall analysis. Lung cancer was found more elevated in workers first exposed in the 1950s and 1960s and in mastic asphalt workers (SIR = 4.2, 95% CI = 1.2, 10, based on four cases) and pavers (SIR = 1.4, 95% CI = 1.0, 1.9). There was a deficiency in the incidence of malignant melanoma with 13 cases versus 26 expected. CONCLUSIONS: Risk of lung cancer was found enhanced among the asphalt workers. Some of the enhanced risk could probably be explained by the smoking habits of the workers. Exposure to coal tar may also have contributed to the enhanced risk.
PubMed ID
12494425 View in PubMed
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Mortality from non-malignant diseases among male Norwegian asphalt workers.

https://arctichealth.org/en/permalink/ahliterature187303
Source
Am J Ind Med. 2003 Jan;43(1):96-103
Publication Type
Article
Date
Jan-2003
Author
Britt Grethe Randem
Sverre Langård
Johny Kongerud
Inge Dale
Igor Burstyn
Jan Ivar Martinsen
Aage Andersen
Author Affiliation
Rikshospitalet University Hospital, Centre for Occupational and Environmental Medicine, Oslo, Norway. britt.randem@rikshospitalet.no
Source
Am J Ind Med. 2003 Jan;43(1):96-103
Date
Jan-2003
Language
English
Publication Type
Article
Keywords
Adult
Cohort Studies
Humans
Hydrocarbons
Inhalation Exposure
Male
Norway - epidemiology
Occupational Diseases - mortality
Occupational Exposure
Respiratory Tract Diseases - mortality
Risk assessment
Abstract
The possible associations between asphalt work and mortality from non-malignant diseases in a cohort of male Norwegian asphalt workers that formed part of the European asphalt worker mortality study are examined.
The mortality experience among 8,610 male workers ever employed in asphalt work was observed from 01.01.1970 until 12.31.1996, yielding 127,636 person years of observation. The cause-specific deaths observed in the study cohort were compared with the expected figures calculated from 5-year period- and age-specific national death rates. A study-specific job exposure matrix was used for individual-individual exposure estimates.
Eight hundred and three workers died during the observation period (SMR = 0.92, 95% confidence intervals (CI) = 0.58, 1.40). The mortality from non-malignant respiratory diseases was elevated (SMR = 1.25, 95%CI = 0.97, 1.58) and was associated with years since first employment in the asphalt industry. Mortality from respiratory diseases was highest among the workers first employed in the 1960s. Among the different job types held by the workers the pavers and mastic asphalt workers had the highest mortality from respiratory diseases. A weak dose-response was found with cumulative exposure to PAH and bitumen fume and mortality from non-malignant respiratory diseases in analyses employing the job-exposure matrix. Overall mortality, the mortality from circulatory diseases (SMR = 0.93, 95%CI = 0.83, 1.03) and external causes (SMR = 0.90, 95%CI = 0.72, 1.11) was lower than expected.
Mortality from respiratory diseases was found somewhat elevated among the asphalt workers. There was some evidence of exposure-response with both bitumen fume and PAH exposure. PAH from coal tar contributes to the PAH exposure.
PubMed ID
12494426 View in PubMed
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