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Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite.

https://arctichealth.org/en/permalink/ahliterature274788
Source
Pain Res Manag. 2016;2016:7657329
Publication Type
Article
Date
2016
Author
Kimberly T Sibille
Ólöf A Steingrímsdóttir
Roger B Fillingim
Audun Stubhaug
Henrik Schirmer
Huaihou Chen
Bruce S McEwen
Christopher S Nielsen
Source
Pain Res Manag. 2016;2016:7657329
Date
2016
Language
English
Publication Type
Article
Abstract
Background. Chronic pain is associated with increased morbidity and mortality, predominated by cardiovascular disease and cancer. Investigating related risk factor measures may elucidate the biological burden of chronic pain. Objectives. We hypothesized that chronic pain severity would be positively associated with the risk factor composite. Methods. Data from 12,982 participants in the 6th Tromsø study were analyzed. Questionnaires included demographics, health behaviors, medical comorbidities, and chronic pain symptoms. The risk factor composite was comprised of body mass index, fibrinogen, C-reactive protein, and triglycerides. Chronic pain severity was characterized by frequency, intensity, time/duration, and total number of pain sites. Results. Individuals with chronic pain had a greater risk factor composite than individuals without chronic pain controlling for covariates and after excluding inflammation-related health conditions (p
PubMed ID
27445627 View in PubMed
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