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120 records – page 1 of 12.

Abdominal Aortic Calcifications Predict Survival in Peritoneal Dialysis Patients.

https://arctichealth.org/en/permalink/ahliterature298110
Source
Perit Dial Int. 2018 Sep-Oct; 38(5):366-373
Publication Type
Journal Article
Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't
Author
Satu Mäkelä
Markku Asola
Henrik Hadimeri
James Heaf
Maija Heiro
Leena Kauppila
Susanne Ljungman
Mai Ots-Rosenberg
Johan V Povlsen
Björn Rogland
Petra Roessel
Jana Uhlinova
Maarit Vainiotalo
Maria K Svensson
Heini Huhtala
Heikki Saha
Author Affiliation
Tampere University Hospital, Tampere, Finland satu.m.makela@pshp.fi.
Source
Perit Dial Int. 2018 Sep-Oct; 38(5):366-373
Language
English
Publication Type
Journal Article
Multicenter Study
Observational Study
Research Support, Non-U.S. Gov't
Keywords
Ankle Brachial Index
Aorta, Abdominal - diagnostic imaging
Aortic Diseases - diagnosis - epidemiology - etiology
Cause of Death - trends
Critical Illness - mortality - therapy
Denmark - epidemiology
Estonia - epidemiology
Female
Finland - epidemiology
Humans
Incidence
Male
Middle Aged
Peritoneal Dialysis - adverse effects - mortality
Prognosis
Prospective Studies
Renal Dialysis
Risk factors
Survival Rate - trends
Sweden - epidemiology
Ultrasonography, Doppler
Vascular Calcification - diagnosis - epidemiology - etiology
Abstract
Peripheral arterial disease and vascular calcifications contribute significantly to the outcome of dialysis patients. The aim of this study was to evaluate the prognostic role of severity of abdominal aortic calcifications and peripheral arterial disease on outcome of peritoneal dialysis (PD) patients using methods easily available in everyday clinical practice.
We enrolled 249 PD patients (mean age 61 years, 67% male) in this prospective, observational, multicenter study from 2009 to 2013. The abdominal aortic calcification score (AACS) was assessed using lateral lumbar X ray, and the ankle-brachial index (ABI) using a Doppler device.
The median AACS was 11 (range 0 - 24). In 58% of the patients, all 4 segments of the abdominal aorta showed deposits, while 19% of patients had no visible deposits (AACS 0). Ankle-brachial index was normal in 49%, low ( 1.3) in 34% of patients. Altogether 91 patients (37%) died during the median follow-up of 46 months. Only 2 patients (5%) with AACS 0 died compared with 50% of the patients with AACS = 7 (p
PubMed ID
29386304 View in PubMed
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Adult but no pediatric anaphylaxis-related deaths in the Finnish population from 1996 to 2013.

https://arctichealth.org/en/permalink/ahliterature294745
Source
J Allergy Clin Immunol. 2016 08; 138(2):630-2
Publication Type
Letter
Research Support, Non-U.S. Gov't
Date
08-2016
Author
Juho E Kivistö
Teija Dunder
Jennifer L P Protudjer
Jussi Karjalainen
Heini Huhtala
Mika J Mäkelä
Author Affiliation
Allergy Centre, Tampere University Hospital, Tampere, Finland; Centre for Child Health Research, Tampere University and University Hospital, Tampere, Finland; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: juho.kivisto@uta.fi.
Source
J Allergy Clin Immunol. 2016 08; 138(2):630-2
Date
08-2016
Language
English
Publication Type
Letter
Research Support, Non-U.S. Gov't
Keywords
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Anaphylaxis - etiology - mortality
Cause of Death - trends
Child
Drug Hypersensitivity - complications - mortality
Female
Finland - epidemiology
Food Hypersensitivity - complications - mortality
Humans
Incidence
Insect Bites and Stings - complications - mortality
Male
Middle Aged
Young Adult
PubMed ID
27343204 View in PubMed
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Alcohol consumption and kidney function in IgA glomerulonephritis.

https://arctichealth.org/en/permalink/ahliterature151352
Source
Nephron Clin Pract. 2009;112(2):c86-93
Publication Type
Article
Date
2009
Author
Kati Kaartinen
Onni Niemela
Jaana Syrjanen
Ilkka Porsti
Aimo Harmoinen
Amos Pasternack
Heini Huhtala
Jukka Mustonen
Author Affiliation
Medical School, University of Tampere, Tampere, Finland. kati.kaartinen@elisanet.fi
Source
Nephron Clin Pract. 2009;112(2):c86-93
Date
2009
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Alcohol drinking - epidemiology
Causality
Comorbidity
Female
Finland - epidemiology
Glomerulonephritis, IGA - diagnosis - epidemiology
Humans
Incidence
Kidney Function Tests - statistics & numerical data
Male
Middle Aged
Risk Assessment - methods
Risk factors
Young Adult
Abstract
IgA glomerulonephritis (IgAGN) is a kidney disease with variable prognosis. Several known risk factors exist for a more progressive course. Some population studies indicate that moderate alcohol consumption might protect kidney function, but the relationship between alcohol intake and IgAGN has not previously been examined.
We examined 158 (95 men) IgAGN patients (37 abstainers, 80 light drinkers, 25 moderate drinkers and 16 heavy drinkers) in a cross-sectional study. The definition of alcohol consumption was based on interviews on the amounts of alcohol intake combined with measurements of serum carbohydrate-deficient transferrin, a specific biomarker of alcohol abuse. Longitudinal data on renal function were available from 117 patients (76 men) in whom an analysis with respect to progression was also performed.
Moderate drinkers showed the best kidney function. When adjusted by hypertension and 24-hour protein excretion, moderate alcohol consumption in a cross-sectional multivariate analysis, and both light and moderate alcohol consumption in a longitudinal multivariate analysis were significant factors of better kidney function. When the study population was divided by gender, the best kidney function was among light drinkers in women and among moderate drinkers in men.
Moderate alcohol consumption might have a favorable impact on the progression of IgAGN. Light alcohol consumption in women and moderate consumption in men are associated with improved indices of the glomerular filtration estimates in patients with IgAGN.
PubMed ID
19390207 View in PubMed
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Alexithymia and health-related quality of life in a general population.

https://arctichealth.org/en/permalink/ahliterature152665
Source
Psychosomatics. 2009 Jan-Feb;50(1):59-68
Publication Type
Article
Author
Aino K Mattila
Samuli I Saarni
Jouko K Salminen
Heini Huhtala
Harri Sintonen
Matti Joukamaa
Author Affiliation
Tampere School of Public Health, FIN-33014, University of Tampere, Tampere, Finland. aino.mattila@uta.fi
Source
Psychosomatics. 2009 Jan-Feb;50(1):59-68
Language
English
Publication Type
Article
Keywords
Adult
Affective Symptoms - epidemiology - psychology
Aged
Aged, 80 and over
Female
Finland - epidemiology
Humans
Male
Middle Aged
Prevalence
Psychiatric Status Rating Scales
Quality of Life - psychology
Registries
Abstract
Alexithymia is thought to reflect a deficit in the cognitive processing of emotion, and, therefore, it may predispose individuals to both psychological and somatic symptoms.
The authors investigated the relationship between alexithymia and health-related quality of life (HRQoL) in a nationally representative population sample of 5,418 subjects, age 30 to 97 years.
Alexithymia was measured with the 20-item Toronto Alexithymia Scale (TAS-20) and HRQoL measured with the 15D, a generic HRQoL measure.
Alexithymia was significantly associated with lower HRQoL independently of other variables. The TAS-20 subfactor Difficulties Identifying Feelings was the strongest common denominator between alexithymia and HRQoL.
Alexithymia may be a predisposing factor to poorer HRQoL.
PubMed ID
19213974 View in PubMed
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Ambient temperature and neck EMG with +Gz loading on a trampoline.

https://arctichealth.org/en/permalink/ahliterature162975
Source
Aviat Space Environ Med. 2007 Jun;78(6):574-8
Publication Type
Article
Date
Jun-2007
Author
Roope Sovelius
Juha Oksa
Harri Rintala
Heini Huhtala
Simo Siitonen
Author Affiliation
Training Air Wing, P.O. Box 5, FIN-62201 Kauhava, Finland. roope.sovelius@mil.fi
Source
Aviat Space Environ Med. 2007 Jun;78(6):574-8
Date
Jun-2007
Language
English
Publication Type
Article
Keywords
Adult
Aerospace Medicine
Cold Temperature - adverse effects
Electromyography
Female
Finland
Humans
Hypergravity
Male
Military Personnel
Muscle Tonus - physiology
Neck Muscles - injuries - physiopathology
Seasons
Skin Temperature - physiology
Abstract
Fighter pilots who are frequently exposed to severe cold ambient temperatures experience neck pain disabilities and occupational disorders more often than those who are not so exposed. We hypothesized that a cold-induced increase in muscle strain might lead to in-flight neck injuries. The aims of this study were to measure the level of cooling before takeoff and to determine muscle strain under Gz loading (0 to +4 Gz) at different temperatures.
Test subjects' (n = 14) skin temperature (T(skin)) over the trapezoids was measured before the walk to the aircraft and again in the cockpit (air temperature -14 degrees C). The subjects then performed trampoline exercises in two different ambient temperatures (-2 degrees C and +21 degrees C) after a 30-min period at the respective temperatures. EMG activity of the sternocleidomastoid (SCM), cervical erector spinae (CES), trapezoid (TRA), thoracic erector spinae (TES) muscles, and Tskin of the SCM and TRA were measured.
Tskin over the trapezoids decreased from 30.1 +/- 1.7 degrees C to 27.8 +/- 2.6 degrees C (p
PubMed ID
17571657 View in PubMed
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Anal incontinence: long-term alterations in the incidence and healthcare usage.

https://arctichealth.org/en/permalink/ahliterature260828
Source
Scand J Gastroenterol. 2014 Jul;49(7):790-3
Publication Type
Article
Date
Jul-2014
Author
Kirsi Lehto
Katariina Ylönen
Marja Hyöty
Pekka Collin
Heini Huhtala
Petri Aitola
Source
Scand J Gastroenterol. 2014 Jul;49(7):790-3
Date
Jul-2014
Language
English
Publication Type
Article
Keywords
Adult
Aged
Aged, 80 and over
Case-Control Studies
Chronic Disease
Fecal Incontinence - epidemiology - therapy
Female
Finland - epidemiology
Follow-Up Studies
Health Services - statistics & numerical data - utilization
Humans
Incidence
Male
Middle Aged
Quality of Life
Questionnaires
Abstract
The aim of the study was to determine the alterations in the occurrence of incontinence and how subjects suffering from incontinence seek and receive healthcare services over a 10-year follow-up period.
Postal questionnaires (Wexner Incontinence Score, Fecal Incontinence Quality of Life Scale, a questionnaire to investigate the management of fecal incontinence and the frequency of urinary incontinence) were sent to subjects who had reported anal incontinence in our population-based study in 2003. For each incontinent person (n = 155) from the 2003 series, we identified two control subjects (n = 310) who did not suffer from incontinence.
Of the initially incontinent, 47 (58%) had remained incontinent after a follow up of 10 years. Almost 80% of the incontinent subjects in 2012 were female. Of the 152 initially continent, 12 (7.9%) had developed symptoms, all of whom were females. Urinary incontinence was present in approximately 60% of incontinent subjects. The majority (57.8%) of the subjects still incontinent in 2012 felt that they needed help for the complaint, but only 30.9% had received any, and only 7.4% received any benefit. The most common treatment was medication. The subjective incontinence impaired the quality of life.
Incontinence is a chronic long-lasting disorder. The current management of anal incontinence is not satisfactory. The primary healthcare system should be more aware of the nature of this condition to find and offer treatment for the patients.
PubMed ID
24873896 View in PubMed
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Anatomic and functional assessment and risk factors of recurrent prolapse after vaginal sacrospinous fixation.

https://arctichealth.org/en/permalink/ahliterature185342
Source
Acta Obstet Gynecol Scand. 2003 May;82(5):471-8
Publication Type
Article
Date
May-2003
Author
Kari Nieminen
Heini Huhtala
Pentti K Heinonen
Author Affiliation
Department of Obstetrics and Gynecology, Tampere University Hospital and Medical School and School of Public Health, University of Tampere, Tampere, Finland. kn37975@uta.fi
Source
Acta Obstet Gynecol Scand. 2003 May;82(5):471-8
Date
May-2003
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Antibiotic Prophylaxis
Broad Ligament - surgery
Female
Finland
Gynecologic Surgical Procedures - adverse effects - methods
Humans
Middle Aged
Multivariate Analysis
Pelvic Floor - surgery
Proportional Hazards Models
Pulmonary Embolism - etiology
Quality of Life
Recurrence
Retrospective Studies
Risk factors
Sacrococcygeal Region - physiopathology - surgery
Time Factors
Urinary Tract Infections - etiology
Uterine Prolapse - physiopathology - surgery
Vagina - surgery
Abstract
To identify risk factors in recurrence and to evaluate anatomic and functional results of vaginal sacrospinous ligament fixation and pelvic floor reconstruction for genital prolapse.
One hundred and thirty-eight women underwent surgery for uterovaginal or vault prolapse. Follow-up data were available for 122 cases; 83% were examined and others were interviewed by telephone. The median (range) follow-up was 24 (1-141) months. Cox regression was used to identify risk factors associated with recurrence; uni- and multivariate regression was used to identify risk factors underlying postoperative infections because infections were found to be a risk factor of recurrence. Recurrence-free survival was estimated using the Kaplan-Meier method.
Seven (5%) patients suffered severe cardiopulmonary complications including one postoperative death due to a pulmonary embolism. Twenty-six (21%) patients suffered a recurrence, 14 with cystocele. Ten patients with recurrence were symptomatic and six underwent a re-operation. The Cox regression model showed that vaginal cuff infection raised the odds ratio (OR) for recurrence to 6.13 [confidence interval (CI) 1.80-20.83] and urinary tract infection to 3.65 (CI 1.40-9.47). In both uni- and multivariate analysis, lack of intravenous antibiotic prophylaxis, age less than 73 years and vaginal ulcerations were statistically significant risk factors for postoperative infection. Eleven (33%) out of 33 sexually active women reported improvement and three (9%) complained of dyspareunia.
Transvaginal sacrospinous ligament fixation with pelvic floor repair is an effective means of correcting both vault prolapse and uterine procidentia. Women who wish to preserve coital function will also benefit from this operation. Postoperative infection is an independent and most important individual risk factor underlying recurrence. Prophylactic antibiotics seem to be effective in reducing the rate of postoperative infections.
PubMed ID
12752079 View in PubMed
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An outbreak of human metapneumovirus in a rehabilitation center for alcoholics in Tampere, Finland.

https://arctichealth.org/en/permalink/ahliterature269590
Source
Infect Dis (Lond). 2015 Jul;47(7):499-503
Publication Type
Article
Date
Jul-2015
Author
Outi Laine
Janne Laine
Petrus Säilä
Heini Huhtala
Jaana Syrjänen
Tytti Vuorinen
Risto Vuento
Source
Infect Dis (Lond). 2015 Jul;47(7):499-503
Date
Jul-2015
Language
English
Publication Type
Article
Keywords
Aged
Antibodies, Viral - blood
Disease Outbreaks
Female
Finland - epidemiology
Humans
Male
Metapneumovirus - classification - isolation & purification
Middle Aged
Paramyxoviridae Infections - diagnosis - epidemiology - virology
Substance Abuse Treatment Centers
Viral Load
Abstract
Reports of respiratory tract infections in a rehabilitation center for alcoholics triggered the epidemiological investigations in Tampere, Finland. Twenty-nine out of 40 residents (attack rate 73%) and four members of staff fulfilled the case criteria: cough; worsening of dyspnea; or rhinitis with or without fever. Ten cases were hospitalized, one needed treatment in the intensive care unit. All cases recovered. Serum hMPV antibody titer was high (10 240 or more) in 20 (69%) of the 29 tested cases and the difference was significant when compared with the titer measured from the voluntary laboratory personnel (n = 14, p
PubMed ID
25761612 View in PubMed
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Antibodies against deamidated gliadin peptides in early-stage celiac disease.

https://arctichealth.org/en/permalink/ahliterature139417
Source
J Clin Gastroenterol. 2011 Sep;45(8):673-8
Publication Type
Article
Date
Sep-2011
Author
Kalle Kurppa
Katri Lindfors
Pekka Collin
Päivi Saavalainen
Jukka Partanen
Katri Haimila
Heini Huhtala
Kaija Laurila
Markku Mäki
Katri Kaukinen
Author Affiliation
Pediatric Research Centre, University of Tampere, Helsinki, Finland.
Source
J Clin Gastroenterol. 2011 Sep;45(8):673-8
Date
Sep-2011
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Antibodies - blood
Atrophy
Autoantibodies - blood
Biological Markers - blood
Biopsy
Case-Control Studies
Celiac Disease - diagnosis - diet therapy - immunology - pathology
Diet, Gluten-Free
Early Diagnosis
Enzyme-Linked Immunosorbent Assay
Female
Finland
Gliadin - immunology
Humans
Intestinal Mucosa - immunology - pathology
Intestine, Small - immunology - pathology
Male
Middle Aged
Peptide Fragments - immunology
Predictive value of tests
Sensitivity and specificity
Time Factors
Transglutaminases - immunology
Treatment Outcome
Young Adult
Abstract
The widely used serum endomysial (EmA) and transglutaminase 2 (TG2-ab) antibodies predict forthcoming villous damage and celiac disease when the small-bowel mucosa structure is still normal. However, these autoantibodies may remain negative in this early stage of the disease. We hypothesized that the antibodies against deamidated gliadin peptides (DGP-AGA) might appear before the other antibodies and would thus be useful in the diagnosis and follow-up of patients with early-stage celiac disease.
Serum DGP-AGA, TG2-ab, and EmA were measured at baseline and after 1 year on a gluten-free diet in 42 adults proven to have early-stage celiac disease despite normal small-bowel mucosal morphology (Marsh I-II), and in 20 celiac subjects evincing villous atrophy (Marsh III). Thirty-nine subjects with no signs of celiac disease served as nonceliac controls.
Sensitivity to detect early-stage celiac disease was 79% for DGP-AGA, 64% for TG2-ab, and 81% for EmA. Specificities were 95%, 100%, and 100%, respectively. The corresponding efficiencies of the tests were 89% for DGP-AGA, 81% for TG2-ab, and 91% for EmA. All 3 antibodies were significantly decreased on a gluten-free diet.
This study showed that the sensitivity of DGP-AGA was superior to TG2-ab and comparable to EmA in celiac patients having early-stage celiac disease with normal villous morphology. On the basis of these results, DGP-AGA would seem to offer a promising new method for case-finding and follow-up in this entity.
PubMed ID
21063208 View in PubMed
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Anticipated acceptance of HPV vaccination at the baseline of implementation: a survey of parental and adolescent knowledge and attitudes in Finland.

https://arctichealth.org/en/permalink/ahliterature164024
Source
J Adolesc Health. 2007 May;40(5):466-9
Publication Type
Article
Date
May-2007
Author
Sarah C Woodhall
Matti Lehtinen
Tiina Verho
Heini Huhtala
Mari Hokkanen
Elise Kosunen
Author Affiliation
University of Tampere, Tampere, Finland.
Source
J Adolesc Health. 2007 May;40(5):466-9
Date
May-2007
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Analysis of Variance
Female
Finland
Health Knowledge, Attitudes, Practice
Humans
Logistic Models
Male
Middle Aged
Papillomavirus Infections - prevention & control
Papillomavirus Vaccines - administration & dosage
Parental Consent - statistics & numerical data
Patient Acceptance of Health Care - statistics & numerical data
Probability
Questionnaires
Risk assessment
Vaccination - standards - trends
Abstract
We evaluated acceptance of human papillomavirus (HPV) vaccination by adolescents and their parents, 83% and 86% of whom accepted vaccination. Improving knowledge and awareness of HPV, and addressing parental concerns about vaccinating adolescents, most notably on vaccinating against a sexually transmitted disease, should help tackle factors associated with being resistant to accepting HPV vaccination.
PubMed ID
17448408 View in PubMed
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120 records – page 1 of 12.