Skip header and navigation

3 records – page 1 of 1.

Bone mineral density in femoral neck is positively correlated to circulating insulin-like growth factor (IGF)-I and IGF-binding protein (IGFBP)-3 in Swedish men.

https://arctichealth.org/en/permalink/ahliterature190890
Source
Calcif Tissue Int. 2002 Jan;70(1):22-9
Publication Type
Article
Date
Jan-2002
Author
P. Gillberg
H. Olofsson
H. Mallmin
W F Blum
S. Ljunghall
A G Nilsson
Author Affiliation
Department of Medical Sciences, University Hospital, S-75185 Uppsala, Sweden.
Source
Calcif Tissue Int. 2002 Jan;70(1):22-9
Date
Jan-2002
Language
English
Publication Type
Article
Keywords
Absorptiometry, Photon
Adult
Aged
Aged, 80 and over
Aging - physiology
Bone Density
Femur Neck - metabolism - radiography
Gonadal Steroid Hormones - blood
Humans
Insulin-Like Growth Factor Binding Protein 3 - blood
Insulin-Like Growth Factor I - analysis
Lumbar Vertebrae - metabolism - radiography
Male
Middle Aged
Regression Analysis
Sweden
Abstract
Studies on the hormonal regulation of bone metabolism in men have indicated covariation between insulin-like growth factor-I (IGF-I) and sex hormones with bone mineral density (BMD). In this study the relationships between BMD in total body, lumbar spine, femoral neck, distal and ultradistal (UD) radius and circulating levels of IGFs, IGF binding proteins (IGFBPs), and sex steroids were investigated in 55 Swedish men between 22 and 85 (52 +/- 18, mean +/- SD) years of age. BMD in total body, distal and UD radius, and femoral neck was positively correlated with serum IGF-I (r = 0.31 to 0.49), IGF-II (r = 0.32 to 0.48), IGFBP-3 (r = 0.37 to 0.53), and free androgen index (FAI) (r = 0.32 to 0.40), and negatively with IGFBP-1 (r = -0.37 to -0.41) and IGFBP-2 (r = -0.29 to -0.41) levels. A positive correlation was observed between BMD in femoral neck and estradiol/SHBG ratio (r = 0.34, P = 0.01). Age correlated negatively with serum IGF-I, IGF-II, IGFBP-3, FAI, estradiol/SHBG ratio, and BMD in total body, distal and UD radius, and femoral neck, and positively with IGFBP-1, IGFBP-2, and SHBG levels. According to stepwise multiple regression analyses, a combination of weight, IGFBP-3, and testosterone accounted for 43% of the variation in BMD in femoral neck, 34% in ultradistal radius and 48% in total body (P
PubMed ID
11907704 View in PubMed
Less detail

[Larva migrans--tropical worm disease brought along from distant bathing beaches]

https://arctichealth.org/en/permalink/ahliterature40076
Source
Lakartidningen. 1983 Aug 10;80(32-33):2914-5
Publication Type
Article
Date
Aug-10-1983

A painful, never ending story: older women's experiences of living with an osteoporotic vertebral compression fracture.

https://arctichealth.org/en/permalink/ahliterature279196
Source
Osteoporos Int. 2016 May;27(5):1729-36
Publication Type
Article
Date
May-2016
Author
H K Svensson
E H Olofsson
J. Karlsson
T. Hansson
L-E Olsson
Source
Osteoporos Int. 2016 May;27(5):1729-36
Date
May-2016
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Attitude to Health
Chronic Pain - etiology
Fear
Female
Fractures, Compression - complications - psychology - rehabilitation
Health Knowledge, Attitudes, Practice
Humans
Interviews as Topic
Osteoporotic Fractures - complications - psychology - rehabilitation
Social Isolation
Spinal Fractures - complications - psychology - rehabilitation
Sweden
Abstract
Vertebral compression fractures (VCF) cause pain and decreased physical ability, with no known well-established treatment. The aim of this study was to illuminate the experience of living with a VCF. The results show that fear and concerns are a major part of daily life. The women's initial contact with health-care providers should focus on making them feel acknowledged by offering person-centered and tailored support.
In the past decade, osteoporotic-related fractures have become an increasingly common and costly public health problem worldwide. Vertebral compression fracture (VCF) is the second most common osteoporotic fracture, and patients with VCF describe an abrupt descent into disability, with a subsequent desire to regain independence in everyday life; however, little is known of their situation. The aim of this study was to illuminate the lived experience of women with an osteoporotic VCF.
Ten women were interviewed during 2012-2013, starting with an open-ended question: could you tell me what it is like to live with a vertebral compression fracture? The verbatim transcribed interviews were analyzed using a phenomenological hermeneutical approach.
The narrative provided descriptions of living in turmoil and chaos, unable to find stability in their life with little improvement regarding pain and physical function. Shifts from periods of constant pain to periods of fear of constant pain created a loss of confidence and an increased sense of confinement. The structural analysis revealed fear and concerns as the most prominent experience building on five themes: struggling to understand a deceiving body, breakthrough pain fueling fear, fearing a trajectory into isolation, concerns of dependency, and fearing an uncertain future.
Until researchers find a successful prevention or medical/surgical treatment for osteoporotic VCFs, health-care providers and society abandon these women to remain in a painful and never ending story.
Notes
Cites: Scand J Caring Sci. 2000;14(1):16-2212035257
Cites: Scand J Caring Sci. 2013 Sep;27(3):516-2422924528
Cites: Geriatr Nurs. 2013 Jul-Aug;34(4):289-9423669314
Cites: Age (Dordr). 2014 Feb;36(1):483-9323990275
Cites: ANS Adv Nurs Sci. 2000 Sep;23(1):12-2810970036
Cites: Int J Qual Stud Health Well-being. 2014;9:2243824559545
Cites: J Bone Miner Res. 2003 Jul;18(7):1254-6012854835
Cites: World Health Organ Tech Rep Ser. 2003;919:i-x, 1-218, back cover14679827
Cites: Scand J Caring Sci. 2004 Jun;18(2):145-5315147477
Cites: ANS Adv Nurs Sci. 1996 Mar;18(3):27-368660010
Cites: Osteoporos Int. 2005 May;16(5):447-5515609073
Cites: Nurse Pract. 2005 Nov;30(11):48, 53-816276300
Cites: Osteoporos Int. 2006;17(3):355-6316341623
Cites: J Clin Nurs. 2007 May;16(5):853-917462035
Cites: Spine J. 2008 Sep-Oct;8(5):756-6218343730
Cites: Eur Spine J. 2008 Oct;17(10):1380-9018751742
Cites: Wien Med Wochenschr. 2009 May;159(9-10):235-4019484206
Cites: Health Soc Care Community. 2009 Jul;17(4):379-8719187421
Cites: Nurse Educ Today. 2009 Oct;29(7):735-919427716
Cites: Eur J Radiol. 2009 Sep;71(3):392-719716672
Cites: J Bone Miner Res. 2012 May;27(5):1159-6622513649
Cites: Clin Rehabil. 2012 Nov;26(11):1021-3122498664
Cites: Qual Health Res. 2012 Dec;22(12):1647-5822923385
Cites: Health Qual Life Outcomes. 2012;10:10122920839
Cites: Clin Interv Aging. 2013;8:605-823807842
PubMed ID
26659067 View in PubMed
Less detail