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Current status of cryptococcosis in Canada.

https://arctichealth.org/en/permalink/ahliterature103187
Source
Mycoses. 1990 Feb;33(2):73-80
Publication Type
Article
Date
Feb-1990
Author
A S Sekhon
S N Bannerjee
B M Mielke
H. Idikio
G. Wood
J M Dixon
Author Affiliation
National Reference Centre for Human Mycotic Diseases, Provincial Laboratory of Public Health, Edmonton, Canada.
Source
Mycoses. 1990 Feb;33(2):73-80
Date
Feb-1990
Language
English
Publication Type
Article
Keywords
Acquired Immunodeficiency Syndrome - complications
Adolescent
Adult
Aged
Aged, 80 and over
Canada - epidemiology
Child
Cryptococcosis - complications - epidemiology
Female
Humans
Male
Middle Aged
Sex Factors
Abstract
The concurrent use of microscopic, cultural, histopathologic and immunologic procedures enabled us to diagnose 91 cases of cryptococcosis, belonging to cutaneous, pulmonary, meningeal and disseminated types, from the time this mycosis was first reported in Canada in 1953 to the present. These cases occurred predominantly in Quebec (43%) followed by Alberta, British Columbia, Ontario, Saskatchewan, Manitoba, New Brunswick and Newfoundland. It is not known whether any Cryptococcus neoformans infections have occurred elsewhere in Canada. The clinical and laboratory findings indicate that infections occurred in debilitated as well as nondebilitated individuals. Nearly 25% of the infections were seen in individuals having the acquired immune deficiency syndrome (AIDS) in provinces of Alberta, British Columbia, Ontario and Quebec. In some of the AIDS cases, the latex agglutination (LA) test demonstrated exceptionally high titres of circulating cryptococcal antigen (1:256 to 1:32,768). Cr. neoformans infections occurred more commonly in males than in females, and there were 11 fatal cases of cryptococcosis. The incidence of Cr. neoformans in Canada is probably higher than our data suggest because cryptococcosis is not notifiable in Canada and underreporting is likely.
PubMed ID
2352543 View in PubMed
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Source
Can J Surg. 1982 Jan;25(1):83-5
Publication Type
Article
Date
Jan-1982
Author
C. Heughan
D. Kepkay
A M Cruz
H. Idikio
Source
Can J Surg. 1982 Jan;25(1):83-5
Date
Jan-1982
Language
English
Publication Type
Article
Keywords
Adult
Aged
Female
Humans
Male
Middle Aged
Newfoundland and Labrador
Stomach Neoplasms - diagnosis - epidemiology - surgery
Abstract
Early gastric cancer confined to the mucosa or submucosa, similar to that described in the Japanese literature, exists in Newfoundland, on area of North America in which gastric cancer is four times more prevalent that on the rest of the continent. If untreated, this early gastric cancer will progress to advanced disease. The clinical presentation of 10 patients suffering from cancer confined to the mucosa and submucosa of the stomach is described. The disease presents with acute or chronic bleeding or unexplained dyspepsia; no abnormality of the stomach can be seen on roentgenograms. The diagnosis may be suspected at endoscopic examination. Cytologic studies using touch preparations may be suggestive but the diagnosis should be confirmed by biopsy before operation is performed.
PubMed ID
7055771 View in PubMed
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