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Ablation for atrial fibrillation during mitral valve surgery: 1-year results through continuous subcutaneous monitoring.

https://arctichealth.org/en/permalink/ahliterature125117
Source
Interact Cardiovasc Thorac Surg. 2012 Jul;15(1):37-41
Publication Type
Article
Date
Jul-2012
Author
Alexandr Bogachev-Prokophiev
Sergey Zheleznev
Alexander Romanov
Evgeny Pokushalov
Alexey Pivkin
Giorgio Corbucci
Alexander Karaskov
Author Affiliation
Department of Heart Valves Surgery, State Research Institute of Circulation Pathology, Novosibirsk, Russian Federation. b-pav@rambler.ru
Source
Interact Cardiovasc Thorac Surg. 2012 Jul;15(1):37-41
Date
Jul-2012
Language
English
Publication Type
Article
Keywords
Atrial Fibrillation - complications - diagnosis - mortality - surgery
Atrial Flutter - diagnosis - etiology - mortality
Catheter Ablation - adverse effects - mortality
Chi-Square Distribution
Disease-Free Survival
Electrocardiography, Ambulatory
Female
Heart Valve Diseases - complications - mortality - surgery
Heart Valve Prosthesis Implantation - adverse effects - mortality
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Mitral Valve - surgery
Predictive value of tests
Prospective Studies
Recurrence
Risk assessment
Risk factors
Russia
Time Factors
Treatment Outcome
Abstract
Continuous monitoring of cardiac rhythm may play an important role in measuring the true symptomatic/asymptomatic atrial fibrillation (AF) burden and improve the management of anti-arrhythmic and anti-thrombotic therapies. Forty-seven patients with mitral valve disease and longstanding persistent AF (LSPAF) underwent a left atrial maze procedure with bipolar radiofrequency and valve surgery. The follow-up data recorded by an implanted loop recorder were analysed after 3, 6 and 12 months. On discharge, 40 (85.1%) patients were in stable sinus rhythm, as documented by in-office electrocardiography (ECG), 4 (8.5%) were in pacemaker rhythm and 3 (6.4%) were in AF. One (2.1%) patient died after 7 months. On 12-month follow-up examination, 30 (65.2%) patients had an AF burden 0.5%. Two (4.3%) patients with AF recurrences were completely asymptomatic. Among the symptomatic events stored by the patients, only 27.6% was confirmed as genuine AF recurrences according to the concomitant ECG recorded by the implanted loop recorder. A concomitant bipolar maze procedure during mitral valve surgery is effective in treating AF, as proved by detailed 1-year continuous monitoring.
Notes
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PubMed ID
22514258 View in PubMed
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Cardiac resynchronization therapy and bone marrow cell transplantation in patients with ischemic heart failure and electromechanical dyssynchrony: a randomized pilot study.

https://arctichealth.org/en/permalink/ahliterature134723
Source
J Cardiovasc Transl Res. 2011 Dec;4(6):767-78
Publication Type
Article
Date
Dec-2011
Author
Evgeny Pokushalov
Alexander Romanov
Giorgio Corbucci
Darya Prohorova
Alexander Chernyavsky
Petr Larionov
Igor Terekhov
Sergey Artyomenko
Elena Kliver
Natalya Shirokova
Alexander Karaskov
Nabil Dib
Author Affiliation
State Research Institute of Circulation Pathology, Novosibirsk, Russia. E.Pokushalov@gmail.com
Source
J Cardiovasc Transl Res. 2011 Dec;4(6):767-78
Date
Dec-2011
Language
English
Publication Type
Article
Keywords
Aged
Bone Marrow Transplantation - adverse effects
Bundle-Branch Block - diagnosis - etiology - physiopathology - therapy
Cardiac Resynchronization Therapy - adverse effects
Chi-Square Distribution
Combined Modality Therapy
Coronary Circulation
Cross-Over Studies
Echocardiography, Doppler
Exercise Test
Female
Heart Failure - diagnosis - etiology - physiopathology - therapy
Humans
Male
Middle Aged
Myocardial Ischemia - complications - diagnosis - physiopathology - therapy
Myocardial Perfusion Imaging - methods
Pilot Projects
Predictive value of tests
Quality of Life
Questionnaires
Recovery of Function
Russia
Single-Blind Method
Stroke Volume
Time Factors
Tomography, Emission-Computed, Single-Photon
Treatment Outcome
Ventricular Dysfunction, Left - diagnosis - etiology - physiopathology - therapy
Ventricular Function, Left
Abstract
Most studies have confirmed the beneficial effects of autologous bone marrow mononuclear cell (BMMC) transplantation on angina, myocardial perfusion, regional wall motion, and LV ejection fraction (LVEF). Cardiac resynchronization therapy (CRT) has also shown a beneficial effect in patients with heart failure (HF) and electrical/mechanical dyssynchrony. However, the relative contribution of BMMC and CRT in patients with ischemic HF and electromechanical dyssynchrony has never been investigated. The aim of this study was to evaluate the benefit of combining BMMC transplantation with CRT in patients with severe ischemic HF, left bundle branch block (LBBB), and mechanical dyssynchrony. Patients with ischemic HF, LVEF?
PubMed ID
21547598 View in PubMed
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Use of an implantable monitor to detect arrhythmia recurrences and select patients for early repeat catheter ablation for atrial fibrillation: a pilot study.

https://arctichealth.org/en/permalink/ahliterature131176
Source
Circ Arrhythm Electrophysiol. 2011 Dec;4(6):823-31
Publication Type
Article
Date
Dec-2011
Author
Evgeny Pokushalov
Alexander Romanov
Giorgio Corbucci
Sergey Artyomenko
Alex Turov
Natalya Shirokova
Alexander Karaskov
Author Affiliation
State Research Institute of Circulation Pathology, Novosibirsk, Russia. E.Pokushalov@gmail.com
Source
Circ Arrhythm Electrophysiol. 2011 Dec;4(6):823-31
Date
Dec-2011
Language
English
Publication Type
Article
Keywords
Aged
Analysis of Variance
Anti-Arrhythmia Agents - therapeutic use
Atrial Fibrillation - diagnosis - physiopathology - surgery
Catheter Ablation - adverse effects
Chi-Square Distribution
Electrocardiography, Ambulatory - instrumentation
Equipment Design
Female
Heart rate
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Patient Selection
Pilot Projects
Predictive value of tests
Prospective Studies
Pulmonary Veins - physiopathology - surgery
Recurrence
Reoperation
Russia
Time Factors
Treatment Outcome
Abstract
Catheter ablation of atrial fibrillation (AF) has proved effective in curing highly symptomatic patients with paroxysmal AF. The aim of this prospective, randomized study was to identify the optimal treatment of patients with AF recurrences after the first ablation.
Two hundred eighty-six patients with paroxysmal AF underwent ablation (circumferential pulmonary vein isolation with linear lesions) and were monitored with an implantable cardiac monitor (Reveal XT, Medtronic). Patients without AF recurrences during the 3-month postablation period were assigned to group 1; those with AF recurrences to group 2. Patients in group 2 were randomly assigned to group 3 or group 4. Group 3 patients were treated only with antiarrhythmic drugs for 6 weeks, with no early reablation during the 3-month postablation period. In the case of AF recurrence after the 3-month postablation period, patients underwent reablation. Group 4 patients were treated according to the onset mechanism of AF recurrences, as detected and stored by the implantable cardiac monitor: antiarrhythmic drug therapy, but no reablation if AF was not preceded by triggers; early reablation if premature atrial beats or atrial tachycardias or flutter triggered AF. All patients were followed up for 1 year to assess maintenance of sinus rhythm in each group. On 12-month follow-up examination, of the 119 (42%) patients in group 1, 112 (94%) had no AF recurrences. Among the 83 patients in group 3, only 27 (33%) had no recurrences. Of the 84 group 4 patients, 67 (80%) had no AF recurrences (P
Notes
Comment In: Circ Arrhythm Electrophysiol. 2011 Dec;4(6):791-322203657
PubMed ID
21930653 View in PubMed
Less detail