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Affect regulation and psychopathology in women with borderline personality disorder.

https://arctichealth.org/en/permalink/ahliterature118764
Source
Dan Med J. 2012 Nov;59(11):A4521
Publication Type
Article
Date
Nov-2012
Author
Rune Andersen
Nina Timmerby
Erik Simonsen
Author Affiliation
Psykiatrisk Forskningsenhed, Region Sjælland, Roskilde, Denmark. runan@regionsjaelland.dk
Source
Dan Med J. 2012 Nov;59(11):A4521
Date
Nov-2012
Language
English
Publication Type
Article
Keywords
Adult
Affect
Affective Symptoms - etiology
Aggression - psychology
Borderline Personality Disorder - complications - diagnosis - psychology
Denmark
Diagnostic and Statistical Manual of Mental Disorders
Female
Humans
Impulsive Behavior - etiology
Interpersonal Relations
Middle Aged
Personality Inventory - standards - statistics & numerical data
Psychiatric Status Rating Scales
Psychometrics
Psychopathology
Self Report
Self-Injurious Behavior - etiology
Translating
Abstract
Dysfunction in affect regulation is a prominent feature that grossly impairs behavioural and interpersonal domains of experience and underlies a great deal of the psychopathology in borderline personality disorder (BPD). However, no study has yet been published that evaluates the psychometric properties of the translated Danish version of self-report measures sensitive to the different aspects and dimensions of dysfunction in affect regulation prevalent in BPD.
This study comprised a group of women diagnosed with BPD (n = 29) and a comparison group of healthy subjects (n = 29) who reported psychopathology and levels of affective instability, aggression, impulsivity and alexithymia by self-report measures.
Our results demonstrated that women with BPD have significant psychopathology and report significantly higher levels of dysfunction in separate components of affect regulation by self-report measures than the comparison group of healthy subjects. Our results also provided partial support for the psychometric appropriateness and clinical relevance of the translated Danish version of affect regulation measures.
The normative reference range indicated by our results makes the measures useful as a practical assessment tool.
not relevant.
PubMed ID
23171744 View in PubMed
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Determinants of duration of untreated psychosis among first-episode psychosis patients in Denmark: A nationwide register-based study.

https://arctichealth.org/en/permalink/ahliterature295757
Source
Schizophr Res. 2018 02; 192:154-158
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
02-2018
Author
Lene Halling Hastrup
Ulrik Helt Haahr
Jens Einar Jansen
Erik Simonsen
Author Affiliation
Psychiatric Research Unit, Region Zealand Psychiatry, Denmark. Electronic address: lhhs@regionsjaelland.dk.
Source
Schizophr Res. 2018 02; 192:154-158
Date
02-2018
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Adolescent
Adult
Age of Onset
Awareness
Demography
Denmark - epidemiology
Early Intervention (Education)
Female
Humans
Male
Psychiatric Status Rating Scales
Psychotic Disorders - diagnosis - epidemiology - psychology
Registries
Young Adult
Abstract
Information on determinants of duration of untreated psychosis (DUP) is still needed to inform campaigns targeting people with first episode psychosis (FEP). This nation-wide study analysed the association between demographic factors (age, sex, ethnicity, marital status, and geographic area), premorbid and illness-related factors (global functional level, substance misuse, and contact to police), healthcare factors (referral source and first FEP contact) and DUP.
The study population of 1266 patients aged 15-25years diagnosed with FEP (ICD10 F20.0-F20.99) was drawn from the Danish National Indicator Project during 2009-2011. The study population was combined with data from national administrative registers. A multinomial regression model was estimated to analyse the impact of demographic, premorbid and illness-related, and healthcare factors on DUP.
One third of the population had a DUP below 6months. DUP longer than 12months was associated with older age at onset, being female, having cannabis misuse, and living in peripheral municipalities. Being charged by the criminal authorities during one year before FEP was associated with a DUP over 6months.
DUP is related to a number of demographic, premorbid and healthcare factors. These findings suggest that future information campaigns should focus on increasing the awareness of early signs of psychosis not only among mental health professionals but also other professionals in contact with adolescents such as the police. It may also be useful to consider how to target information campaigns towards persons living in peripheral areas.
PubMed ID
28578812 View in PubMed
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Randomised social-skills training and parental training plus standard treatment versus standard treatment of children with attention deficit hyperactivity disorder - the SOSTRA trial protocol.

https://arctichealth.org/en/permalink/ahliterature137704
Source
Trials. 2011;12:18
Publication Type
Article
Date
2011
Author
Ole Jakob Storebø
Jesper Pedersen
Maria Skoog
Per Hove Thomsen
Per Winkel
Christian Gluud
Erik Simonsen
Author Affiliation
Child Psychiatric Daytime Clinic, Child and Adolescent Psychiatric Centre, Region Zealand, Holbaek, Denmark. ojst@regionsjaelland.dk
Source
Trials. 2011;12:18
Date
2011
Language
English
Publication Type
Article
Keywords
Attention Deficit Disorder with Hyperactivity - diagnosis - drug therapy - psychology - therapy
Child
Child Behavior
Cognition
Combined Modality Therapy
Denmark
Emotions
Female
Humans
Male
Parents - psychology
Psychiatric Status Rating Scales
Questionnaires
Research Design
Sample Size
Social Behavior
Time Factors
Treatment Outcome
Abstract
Children with attention deficit hyperactivity disorder (ADHD) are hyperactive and impulsive, cannot maintain attention, and have difficulties with social interactions. Medical treatment may alleviate symptoms of ADHD, but seldom solves difficulties with social interactions. Social-skills training may benefit ADHD children in their social interactions. We want to examine the effects of social-skills training on difficulties related to the children's ADHD symptoms and social interactions.
The design is randomised two-armed, parallel group, assessor-blinded trial. Children aged 8-12 years with a diagnosis of ADHD are randomised to social-skills training and parental training plus standard treatment versus standard treatment alone. A sample size calculation estimated that at least 52 children must be included to show a 4-point difference in the primary outcome on the Conners 3rd Edition subscale for 'hyperactivity-impulsivity' between the intervention group and the control group. The outcomes will be assessed 3 and 6 months after randomisation. The primary outcome measure is ADHD symptoms. The secondary outcome is social skills. Tertiary outcomes include the relationship between social skills and symptoms of ADHD, the ability to form attachment, and parents' ADHD symptoms.
We hope that the results from this trial will show that the social-skills training together with medication may have a greater general effect on ADHD symptoms and social and emotional competencies than medication alone.
ClinicalTrials (NCT): NCT00937469.
Notes
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PubMed ID
21255399 View in PubMed
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Third-wave cognitive therapy versus mentalisation-based treatment for major depressive disorder: a randomised clinical trial.

https://arctichealth.org/en/permalink/ahliterature266353
Source
BMJ Open. 2014;4(8):e004903
Publication Type
Article
Date
2014
Author
Janus Christian Jakobsen
Christian Gluud
Mickey Kongerslev
Kirsten Aaskov Larsen
Per Sørensen
Per Winkel
Theis Lange
Ulf Søgaard
Erik Simonsen
Source
BMJ Open. 2014;4(8):e004903
Date
2014
Language
English
Publication Type
Article
Keywords
Adult
Cognitive Therapy - methods
Denmark
Depressive Disorder, Major - psychology - therapy
Female
Follow-Up Studies
Humans
Male
Psychiatric Status Rating Scales
Theory of Mind
Treatment Outcome
Abstract
To compare the benefits and harms of third-wave cognitive therapy versus mentalisation-based therapy in a small sample of depressed participants.
The trial was conducted at an outpatient psychiatric clinic for non-psychotic patients in Roskilde, Denmark.
44 consecutive adult participants diagnosed with major depressive disorder.
18 weeks of third-wave cognitive therapy (n=22) versus 18 weeks of mentalisation-based treatment (n=22).
The primary outcome was the Hamilton Rating Scale for Depression (HDRS) at end of treatment (18 weeks). Secondary outcomes were: remission (HDRS
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PubMed ID
25138802 View in PubMed
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Treatment and violent behavior in persons with first episode psychosis during a 10-year prospective follow-up study.

https://arctichealth.org/en/permalink/ahliterature259887
Source
Schizophr Res. 2014 Jul;156(2-3):272-6
Publication Type
Article
Date
Jul-2014
Author
Johannes Langeveld
Stål Bjørkly
Bjørn Auestad
Helene Barder
Julie Evensen
Wenche Ten Velden Hegelstad
Inge Joa
Jan Olav Johannessen
Tor Ketil Larsen
Ingrid Melle
Stein Opjordsmoen
Jan Ivar Røssberg
Bjørn Rishovd Rund
Erik Simonsen
Per Vaglum
Thomas McGlashan
Svein Friis
Source
Schizophr Res. 2014 Jul;156(2-3):272-6
Date
Jul-2014
Language
English
Publication Type
Article
Keywords
Adult
Antipsychotic Agents - therapeutic use
Crime
Denmark - epidemiology
Follow-Up Studies
Humans
Logistic Models
Middle Aged
Multivariate Analysis
Norway - epidemiology
Prevalence
Prospective Studies
Psychiatric Status Rating Scales
Psychotherapy
Psychotic Disorders - diagnosis - epidemiology - therapy
Risk
Substance-Related Disorders - epidemiology
Violence
Young Adult
Abstract
First episode psychosis (FEP) patients have an increased risk for violence and criminal activity prior to initial treatment. However, little is known about the prevalence of criminality and acts of violence many years after implementation of treatment for a first episode psychosis.
To assess the prevalence of criminal and violent behaviors during a 10-year follow-up period after the debut of a first psychosis episode, and to identify early predictors and concomitant risk factors of violent behavior.
A prospective design was used with comprehensive assessments of criminal behavior, drug abuse, clinical, social and treatment variables at baseline, five, and 10-year follow-up. Additionally, threatening and violent behavior was assessed at 10-year follow-up. A clinical epidemiological sample of first-episode psychosis patients (n=178) was studied.
During the 10-year follow-up period, 20% of subjects had been apprehended or incarcerated. At 10-year follow-up, 15% of subjects had exposed others to threats or violence during the year before assessment. Illegal drug use at baseline and five-year follow-up, and a longer duration of psychotic symptoms were found to be predictive of violent behavior during the year preceding the 10-year follow-up.
After treatment initiation, the overall prevalence of violence in psychotic patients drops gradually to rates close to those of the general population. However, persistent illicit drug abuse is a serious risk factor for violent behavior, even long after the start of treatment. Achieving remission early and reducing substance abuse may contribute to a lower long-term risk for violent behavior in FEP patients.
PubMed ID
24837683 View in PubMed
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