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Multinucleate cell angiohistiocytoma: a report of four cases in Finland.

https://arctichealth.org/en/permalink/ahliterature184843
Source
Acta Derm Venereol. 2003;83(3):222-3
Publication Type
Article
Date
2003

A retrospective study of the probability of the evolution of parapsoriasis en plaques into mycosis fungoides.

https://arctichealth.org/en/permalink/ahliterature172671
Source
Acta Derm Venereol. 2005;85(4):318-23
Publication Type
Article
Date
2005
Author
Liisa Väkevä
Seppo Sarna
Annikki Vaalasti
Eero Pukkala
Arja-Leena Kariniemi
Annamari Ranki
Author Affiliation
Department of Dermatology and Venereal Diseases, Skin and Allergy Hospital, Helsinki. Finland. liisa.vakeva@hus.fi
Source
Acta Derm Venereol. 2005;85(4):318-23
Date
2005
Language
English
Publication Type
Article
Keywords
Adult
Aged
Cell Transformation, Neoplastic
Cohort Studies
Female
Finland - epidemiology
Humans
Male
Middle Aged
Mycosis Fungoides - drug therapy - epidemiology - etiology - pathology
PUVA Therapy
Psoriasis - complications - pathology
Registries
Retrospective Studies
Skin Neoplasms - drug therapy - epidemiology - etiology - pathology
Abstract
Parapsoriasis en plaque has been suggested to be an early manifestation of mycosis fungoides (cutaneous T-cell lymphoma). We explored the disease course of patients with small plaque or large plaque parapsoriasis in a 26-year retrospective cohort analysis of 105 parapsoriasis patients, who were clinically and histopathologically followed up in Helsinki and Tampere University Hospitals. Eventual later cancers of these patients were verified from the Finnish Cancer Registry. In the small plaque parapsoriasis group, 7 patients (10%) and in the large plaque parapsoriasis group 12 patients (35%), developed histologically confirmed mycosis fungoides during a median of 10 and 6 years, respectively. No significant differences were found regarding the risk of developing mycosis fungoides or the tendency to remission in patients treated with or without phototherapy. Our results show that not only large plaque parapsoriasis, but also small plaque parapsoriasis, as currently defined in textbooks, can progress to mycosis fungoides. The benefits of phototherapy are equivocal in parapsoriasis treatment as far as progression to cancer is concerned.
PubMed ID
16191852 View in PubMed
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