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Clinical and biochemical characteristics of patients with Fusobacterium necrophorum-positive acute tonsillitis.

https://arctichealth.org/en/permalink/ahliterature268251
Source
Eur Arch Otorhinolaryngol. 2015 Jun;272(6):1457-63
Publication Type
Article
Date
Jun-2015
Author
Ann Marlene Gram Kjærulff
Marianne Kragh Thomsen
Therese Ovesen
Tejs Ehlers Klug
Source
Eur Arch Otorhinolaryngol. 2015 Jun;272(6):1457-63
Date
Jun-2015
Language
English
Publication Type
Article
Keywords
Acute Disease
Adolescent
Adult
Denmark - epidemiology
Female
Fusobacterium Infections - complications - diagnosis - epidemiology
Fusobacterium necrophorum - isolation & purification
Humans
Male
Peritonsillar Abscess - epidemiology - etiology
Prevalence
Prospective Studies
Tonsillitis - complications - epidemiology - microbiology
Abstract
Fusobacterium necrophorum (FN) is the predominant pathogen in peritonsillar abscesses, which is a relatively frequent complication of acute tonsillitis. The study aimed to explore if FN is a significant pathogen in acute tonsillitis, examine the prevalence of FN in acute tonsillitis patients, and describe the clinical and biochemical characteristics of FN-positive patients. A 6-month prospective study was conducted in a Danish general practice with eight physicians. One hundred acute tonsillitis patients and 100 healthy controls aged 15-40 years were included in the study. The prevalence of FN was (non-significantly) higher among acute tonsillitis patients (16 %) compared to healthy individuals (9 %) (P = 0.199). This trend was border significant for patients aged 15-29 years (24 vs 9 %) (P = 0.050). Significantly, more FN-positive patients were men (75 %) compared to patients growing other bacteria (17 %) or mixed oral flora (27 %) (P
PubMed ID
25876001 View in PubMed
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