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[A prognostic model of hepatitis A morbidity].

https://arctichealth.org/en/permalink/ahliterature217434
Source
Zh Mikrobiol Epidemiol Immunobiol. 1994 Sep-Oct;(5):45-9
Publication Type
Article
Author
A A Asratian
B V Boev
V I Vasil'eva
V P Grishin
Source
Zh Mikrobiol Epidemiol Immunobiol. 1994 Sep-Oct;(5):45-9
Language
Russian
Publication Type
Article
Keywords
Adult
Child
Hepatitis A - epidemiology - transmission
Humans
Models, Statistical
Prevalence
Prognosis
Russia - epidemiology
Seasons
Urban Population - statistics & numerical data
Abstract
The growing interest to the study of the processes of the spread of hepatitis A (HA) in big cities of our country has stimulated the development of a new prognostic model at the Gamaleia Research Institute of Epidemiology and Microbiology. The model specifically takes into account a number of factors linked with the dynamics of the development of the disease in 6 stages and some regularities in the seasonal rises of HA morbidity. Quantitative relations in the mathematical model are determined by a system of nonlinear integral-differential equations with the first order partial derivatives and under the integral type boundary conditions, which increases the strictness of modeling of HA. The use of this new model has made it possible to carry out the prognostic-analytical study of HA morbidity among children in Perm and to evaluate a decrease in HA morbidity due to the hypothetical vaccination of children in spring months.
PubMed ID
7879481 View in PubMed
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[Detection of the markers of hepatites B and C and herpesvirus infection during pregnancy].

https://arctichealth.org/en/permalink/ahliterature146157
Source
Zh Mikrobiol Epidemiol Immunobiol. 2009 Sep-Oct;(5):22-7
Publication Type
Article
Author
A A Asratian
E D Danilenko
S M Kazarian
V V Chubarov
S G Mardanly
Source
Zh Mikrobiol Epidemiol Immunobiol. 2009 Sep-Oct;(5):22-7
Language
Russian
Publication Type
Article
Keywords
Biological Markers - blood
Carrier State - blood - epidemiology
Comorbidity
Cytomegalovirus - immunology
Cytomegalovirus Infections - blood - epidemiology
DNA, Viral - blood
Female
Hepacivirus - genetics - immunology - isolation & purification
Hepatitis B - blood - epidemiology
Hepatitis B Antibodies - blood
Hepatitis B Surface Antigens - blood
Hepatitis B virus - genetics - immunology - isolation & purification
Hepatitis C - blood - epidemiology
Hepatitis C Antibodies - blood
Herpes Simplex - blood - epidemiology
Humans
Pregnancy
Pregnancy Complications, Infectious - blood - epidemiology - virology
RNA, Viral - blood
Risk factors
Russia - epidemiology
Seroepidemiologic Studies
Simplexvirus - immunology
Abstract
Identification of clinico-epidemiologic features of pareneteral hepatites (HB and HC) and herpesvirus infections (cytomegalovirus, CMVand herpes simplexvirus, HSV) duringpregnancy.
Two hundred pregnant women as well as 150 women--blood donors who comprised a control group were tested in Cheboksary (Chuvash Republic). There were no persons vaccinated against HB in both groups. Diagnostics of the HB and HC as well as CMV and HSV infections was performed by ELISA--HBsAg, anti-HBs, anti-HBc IgM and IgG, anti-HCV as well as IgM and IgG to CMV and HSV were determined; PCR was used to detect HBV DNA and HCV RNA.
Moderate prevalence of HB and HC markers in pregnant (31% and 3% respectively) and donor women (34% and 2% respectively) as well as widespread prevalence of herpesvirus infections' markers (from 71% to 94.5%) was established. The studied women had no clinical manifestations of HB or HC as well as CMV or HSV infections at the time of the study. The study revealed the following: association between complications of pregnancy and detected markers of HB, HC, and herpesvirus infections according to trimester; detection rate of HBV and HCV markers in combination with CMV and HSV markers in pregnant women; association of pregnancy complications with presence of HB and HC markers with combination of herpesvirus infection markers.
It was shown that pregnant women with presence of markers of studied infections present a risk group for development of miscarriage threat, inflammatory processes in placenta and amniotic membranes, and untrauterine fetal growth retardation.
PubMed ID
20063788 View in PubMed
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[Etiologic structure of viral hepatitis in children based on data from an comprehensive serologic study of hospitalized patients].

https://arctichealth.org/en/permalink/ahliterature232260
Source
Zh Mikrobiol Epidemiol Immunobiol. 1988 Nov;(11):31-5
Publication Type
Article
Date
Nov-1988
Author
N V Vorotyntseva
A R Reizis
A N Drondina
V I Vasil'eva
A A Asratian
Source
Zh Mikrobiol Epidemiol Immunobiol. 1988 Nov;(11):31-5
Date
Nov-1988
Language
Russian
Publication Type
Article
Keywords
Adolescent
Child
Child, Preschool
Female
Hepatitis A - diagnosis - epidemiology
Hepatitis B - diagnosis - epidemiology
Hepatitis B Antibodies - analysis
Hepatitis B Surface Antigens - analysis
Hepatitis C - diagnosis - epidemiology
Hepatitis, Viral, Human - diagnosis - epidemiology - etiology
Hospitalization
Humans
Immunoglobulin M - analysis
Infant
Male
Moscow
Urban Population
Abstract
During a year an overall serological examination of 1,200 children hospitalized with the diagnosis of viral hepatitis was carried out with a view to establish the presence of hepatitis A and hepatitis B markers (anti-HAV IgM, HBsAg, anti-HBs, anti-HBc and anti-HBe IgM) by means of the enzyme immunoassay and radioimmunoassay. The average annual proportion of cases of hepatitis A (61.4%), hepatitis B (20.4%), hepatitis non A, non B (11.2%) and mixed infection (7.0%) among children, as well as seasonal and age-group fluctuations of this proportion, were established. The etiological structure of viral hepatitides, based on commonly accepted clinico-epidemiological diagnostic criteria, was shown to differ from their true etiological structure as determined in accordance with specific serological markers detected in this investigation.
PubMed ID
3146191 View in PubMed
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[HB viral infection in kidney diseases in children].

https://arctichealth.org/en/permalink/ahliterature220817
Source
Zh Mikrobiol Epidemiol Immunobiol. 1993 Jul-Aug;(4):108-12
Publication Type
Article
Author
V V Dlin
M S Ignatova
V I Vasil'eva
A A Asratian
A R Reizis
Source
Zh Mikrobiol Epidemiol Immunobiol. 1993 Jul-Aug;(4):108-12
Language
Russian
Publication Type
Article
Keywords
Adolescent
Analysis of Variance
Biological Markers - blood
Child
Child, Preschool
Hepatitis B - complications - epidemiology - immunology
Hepatitis B Antibodies - blood
Hepatitis B Surface Antigens - blood
Humans
Incidence
Kidney Diseases - epidemiology - etiology - immunology
Russia - epidemiology
Seroepidemiologic Studies
Abstract
A total of 142 children aged 2-15 years with different nephropathies, among them 94 children with glomerulonephritis (GN), 26 children with pyelonephritis and 22 children with oxalate nephropathy, were examined. The diagnosis was histologically confirmed in 36 children. Mesangial proliferative GN was detected in 22 patients and membrane proliferative GN, in 14 children. The presence of the markers of HBV infection (HBsAg, anti-HBs and anti-HBc total immunoglobulins, anti-HBc IgM) was detected in the sera of all patients by the enzyme immunoassay. As the result of this examination, essential changes in the distribution of different markers of HBV infection in children with nephropathies were detected. The combination of HBsAg with anti-HBc IgM proved to be the most characteristic feature of patients with the nephrotic syndrome; this was indicative of active HBV infection, and in patients with the mixed form of GN this combination occurred twice as frequently. The established correlation between the activity of HBV infection and the severity of the course of GN made it possible to suggest the participation of HBV in the pathogenesis of GN. This suggestion was indirectly confirmed by a higher detection rate of HBsAg and anti-HBc IgM in patients with the membrane proliferative form of GN.
PubMed ID
8067105 View in PubMed
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[Incidence and clinical characteristics of non-A, non-B viral hepatitis].

https://arctichealth.org/en/permalink/ahliterature236065
Source
Pediatriia. 1987;(5):37-43
Publication Type
Article
Date
1987

[Tendency and analysis of the epidemic situation in parenteral virus hepatitis B and C in the Russian Federation and a number of its regions].

https://arctichealth.org/en/permalink/ahliterature173011
Source
Zh Mikrobiol Epidemiol Immunobiol. 2005 Jul-Aug;(4):40-5
Publication Type
Article
Author
A A Asratian
O V Isaeva
M I Mikhailov
Source
Zh Mikrobiol Epidemiol Immunobiol. 2005 Jul-Aug;(4):40-5
Language
Russian
Publication Type
Article
Keywords
Carrier state
Health Surveys
Hepatitis B - epidemiology
Hepatitis C - epidemiology
Humans
Incidence
Russia - epidemiology
Abstract
As revealed in the present survey, during the last 3 years, against a background of decreased number of registered cases of acute hepatitis B (HB) and acute hepatitis C (HC), an increase in the proportion of patients with the chronic forms of these diseases was observed. The incidence rate of carriership of hepatitis B (HBV) and hepatitis C viruses (HCV) is many times greater than morbidity rates in acute and chronic forms of the disease. Such differences could be due to imperfect laboratory and clinical diagnosis. The registered statistics on HBV and HCV carriership included newly detected HBsAg and anti-HCV in the absence of clinical manifestations, which did not reflect the true spread of HBV and HCV in a given territory. The group of HBV and HCV carriers was found to include a considerable proportion of patients with asymptomatic form of HB and HC. It was testing for HBsAg, anti-HCV only without determination of virus replication markers (anti-HBc IgM, HBV DNA, anti-HCV IgM, HCV RNA) that seemingly determined the category of carriers greatly exceeding the true incidence. To obtain reliable epidemiological information, the complex detection of HB and HC infection markers is necessary.
PubMed ID
16146226 View in PubMed
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[The morbidity and immunological structure of the population in viral hepatitis A at different phases in the development of multiyear epidemic cycles].

https://arctichealth.org/en/permalink/ahliterature217435
Source
Zh Mikrobiol Epidemiol Immunobiol. 1994 Sep-Oct;(5):42-5
Publication Type
Article
Author
L I Shliakhtenko
L N Kryga
M D Aleinik
V I Vasil'eva
S L Mukomolov
V I Rumovskii
E P Shargorodskaia
A A Asratian
T N Bystrova
Source
Zh Mikrobiol Epidemiol Immunobiol. 1994 Sep-Oct;(5):42-5
Language
Russian
Publication Type
Article
Keywords
Adolescent
Adult
Age Distribution
Child
Child, Preschool
Disease Outbreaks - statistics & numerical data
Hepatitis A - epidemiology - immunology
Hepatitis Antibodies - blood
Hepatovirus - immunology
Humans
Russia - epidemiology
Seroepidemiologic Studies
Time Factors
Urban Population - statistics & numerical data
Abstract
For the first time population immunity to virus hepatitis A has been studied during three different phases of prolonged morbidity cycles of this infection, and the results of this study have been compared with the data on morbidity in different age groups. Pronounced variability of the immunological structure of the population in different age groups, found to be related to the dynamics of hepatitis A morbidity, has been established. Fluctuations in immunity level are most pronounced among children aged 1-6 and 7-14 years, having the least proportion of seropositive persons. A new epidemic cycle is started among these groups of the population, and at the first stage this cycle is manifested by an increase in the intensity of the latently developing epidemic process. This is followed by the activation of registered morbidity among the whole of the population. Seroepidemiological study may be used both for prognostication purposes and in the system of surveillance on this infection.
PubMed ID
7879480 View in PubMed
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[Viral hepatitis A and B as a mixed infection in children].

https://arctichealth.org/en/permalink/ahliterature232228
Source
Zh Mikrobiol Epidemiol Immunobiol. 1988 Nov;(11):27-30
Publication Type
Article
Date
Nov-1988
Author
A R Reizis
A K Drondina
A A Asratian
S G Mardanly
T N Rybalkina
Source
Zh Mikrobiol Epidemiol Immunobiol. 1988 Nov;(11):27-30
Date
Nov-1988
Language
Russian
Publication Type
Article
Keywords
Adolescent
Child
Child, Preschool
Cross Infection - diagnosis - epidemiology
Female
Hepatitis A - diagnosis - epidemiology
Hepatitis B - diagnosis - epidemiology
Hepatitis B Antibodies - analysis
Hepatitis B Surface Antigens - analysis
Hospitalization
Humans
Infant
Male
Moscow
Prognosis
Superinfection - diagnosis - epidemiology
Urban Population
Abstract
Serological examinations of 1,200 children, hospitalized at the viral hepatitis department over a year, for the presence of hepatitis A (HA) and hepatitis B (HB) markers have revealed a 7% incidence rate of mixed HA and HB infections. Three variants of mixed infection have been established (true mixed infection, HA combined with asymptomatic HBsAg carriership, cross superinfection) and the relative significance of each of them has been determined. Mixed infection took an unfavorable course with a tendency to the prolongation of the pathological process eventuating in chronic hepatitis, especially in cases of true mixed infections (15.9%).
PubMed ID
3218422 View in PubMed
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10 records – page 1 of 1.