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[About Minimization of Expenses on Allergy Diagnosis in Children: Analysis of Consistency of in Vitro- and in Vivo-Allergic Examinations Results].

https://arctichealth.org/en/permalink/ahliterature272621
Source
Vestn Ross Akad Med Nauk. 2015;(6):748-55
Publication Type
Article
Date
2015
Author
M A Snovskaya
A S Batyrova
L S Namazova-Baranova
A A Alekseeva
E A Vishneva
O V Kozhevnikova
A A Marushina
V N Lubov
Source
Vestn Ross Akad Med Nauk. 2015;(6):748-55
Date
2015
Language
Russian
Publication Type
Article
Keywords
Adolescent
Allergens - classification - immunology
Child
Child, Preschool
Cost Savings - methods
Dermatitis, Atopic - blood - diagnosis - economics - etiology
Female
Humans
Immunoglobulin E - analysis - blood
Immunologic Techniques - economics - methods
Male
Needs Assessment
Pollen - classification - immunology
Rhinitis, Allergic, Seasonal - blood - diagnosis - economics - etiology
Russia
Abstract
High morbidity rate of atopic diseases among children, including high importance of grass pollen as a sensitizing agent, determine the relevance ofstudies on diagnostic examination systems for appointment of adequate therapy. The research of the most relevant allergens for patients to excludeof duplicating and uninformative tests became urgent after development of a new type of diagnostic tests that does not require expensive equipment. The objective of this research was to evaluate the results of in vitro- and in vivo-diagnostic examinations of children with various forms of atopic disease caused by pollen of meadow grasses, and to choose the most significant prognostic parameters for the diagnosis.
277 children aged 4-16 years with various forms of atopic disease were included in the study. There were performed skin prick tests and determination of IgE-antibodies levels to allergen extracts of cocksfoot (g3), meadow fescue (g4), timothy grass (g6).
In the studied group of patients 32-50% of children have antibodies to grass allergens. There was a close correlation of antibody response on the investigated allergens, quantitative coincidence of IgE-antibodies to g3 andg4 allergens levels. IgE (g6) concentration was close to the IgE(g3) and IgE(g4) levels (85.0 ± 21.6%). Analysis of the skin tests results showed that 44% of patients have a positive response to grass allergens, and in vivo-tests results coincide with serologicaltests results, mostly in a qualitative sense. The most significant relationship was noted between in vivo and in vitro-tests in the results of testing the response to meadow fescue pollen.
Based on these data IgE concentration index to meadow fescue allergens can be used as a prognostic marker to determine the sensitization of patients with different nosology forms of allergy and can help to improve allergic diagnostics.
PubMed ID
27093804 View in PubMed
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[Herpes simplex in acute viral respiratory diseases].

https://arctichealth.org/en/permalink/ahliterature248476
Source
Vopr Virusol. 1978 Jul-Aug;(4):459-63
Publication Type
Article
Author
R M Bikbulatov
E S Ketiladze
A A Alekseeva
N N Zhilina
Source
Vopr Virusol. 1978 Jul-Aug;(4):459-63
Language
Russian
Publication Type
Article
Keywords
Acute Disease
Adenoviridae Infections - complications
Adenovirus Infections, Human - complications
Adolescent
Adult
Aged
Female
Herpes Simplex - diagnosis - epidemiology - etiology
Humans
Influenza A virus
Influenza, Human - complications
Male
Middle Aged
Moscow
Paramyxoviridae Infections - complications
Respiratory Tract Infections - complications
Seasons
Abstract
Herpes in main viral acute respiratory diseases (ARD) in adults (influenza, parainfluenza, adenovirus and mixed infections) was studied by different laboratory methods of diagnosis. It was found that in 44.5% viral ARD were accompanied by herpes in the clinically overt or latent form. Herpes was detected with varying frequencies depending on the nosological forms of ARD as well as on the nature of the infection: more frequently in monoinfections than in mixed infections.
PubMed ID
219618 View in PubMed
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[Use of rimantadine in familial foci during an epidemic of influenza caused by A1 virus].

https://arctichealth.org/en/permalink/ahliterature248607
Source
Vopr Virusol. 1978 May-Jun;(3):277-82
Publication Type
Article
Author
V F Krylov
E S Ketiladze
E G Smagulova
A A Alekseeva
M M Nefelova
Source
Vopr Virusol. 1978 May-Jun;(3):277-82
Language
Russian
Publication Type
Article
Keywords
Adamantane - analogs & derivatives - therapeutic use
Adolescent
Adult
Aged
Bridged Compounds - therapeutic use
Child
Child, Preschool
Disease Outbreaks - prevention & control
Humans
Influenza A virus
Influenza, Human - diagnosis - genetics - prevention & control
Middle Aged
Moscow
Abstract
The therapeutic and prophylactic efficacy of rimantadine in familial foci during influenza A1 outbreaks was studied. The observations included 28 experimental foci and 26 control (altogether 146 subjects varying in ages from 4 to 71 years). The foci were selected at random (the alphabet principle). In the experimental foci the patients were treated with rimantadine given in single doses of 300 mg on the first day, 200 mg on the second, and 100 mg each on the 3rd and 4th days. The contacts were also given rimantadine, 100 mg each for 7 to 10 days. In the control foci the patients received symptomatic drugs and contacts were only observed by physicians. Rimantadine was shown to be effective therapeutically if the treatment was started on the first day of the disease. As compared with the control group, in the treated patients the temperature became normal and the main symptoms of the disease regressed within shorter periods of time. The prophylactic effect was also positive: in experimental foci repeated diseases occurred only in 3 subjects (6%) and in controls 13 subjects (30%). The prophylactic effectiveness of the drug is also indicated by a decline in the number of inapparent forms: in experimental foci 26%, in control 56%. The drug may be recommended for treatment and prevention of influenza in familial foci when the disease is caused by A1 virus.
PubMed ID
695520 View in PubMed
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