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Prevalence and management of severe asthma in primary care: an observational cohort study in Sweden (PACEHR).

https://arctichealth.org/en/permalink/ahliterature295883
Source
Respir Res. 2018 01 18; 19(1):12
Publication Type
Journal Article
Observational Study
Research Support, Non-U.S. Gov't
Date
01-18-2018
Author
Kjell Larsson
Björn Ställberg
Karin Lisspers
Gunilla Telg
Gunnar Johansson
Marcus Thuresson
Christer Janson
Author Affiliation
Work Environment Toxicology, The National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. kjell.larsson@ki.se.
Source
Respir Res. 2018 01 18; 19(1):12
Date
01-18-2018
Language
English
Publication Type
Journal Article
Observational Study
Research Support, Non-U.S. Gov't
Keywords
Adult
Aged
Aged, 80 and over
Anti-Asthmatic Agents - therapeutic use
Asthma - diagnosis - epidemiology - therapy
Cohort Studies
Disease Management
Female
Humans
Male
Middle Aged
Prevalence
Primary Health Care - methods
Registries
Severity of Illness Index
Sweden - epidemiology
Abstract
Severe and uncontrolled asthma is associated with increased risk of exacerbations and death. A substantial proportion of asthma patients have poor asthma control, and a concurrent COPD diagnosis often increases disease burden. The objective of the study was to describe the prevalence and managemant of severe asthma in a Swedish asthma popuöation.
In this observational cohort study, primary care medical records data (2006-2013) from 36 primary health care centers were linked to data from national mandatory Swedish health registries. The studied population (>18 years) had a record of drug collection for obstructive pulmonary disease (ATC code R03) during 2011-2012, and a physician diagnosed asthma (ICD-10 code J45-J46) prior to drug collection. Severe asthma was classified as collection of high dose inhaled steroid (> 800 budesonide or equivalent per day) and leukotriene receptor antagonist and/or long-acting beta-agonist. Poor asthma control was defined as either collection of =600 doses of short-acting beta-agonists, and/or =1 exacerbation(s) during the year post index date.
A total of 18,724 asthma patients (mean 49 years, 62.8% women) were included, of whom 17,934 (95.8%) had mild to moderate and 790 (4.2%) had severe asthma. Exacerbations were more prevalent in severe asthma (2.59 [2.41-2.79], Relative Risk [95% confidence interval]; p?
Notes
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PubMed ID
29347939 View in PubMed
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