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Active aging - resilience and external support as modifiers of the disablement outcome: AGNES cohort study protocol.

https://arctichealth.org/en/permalink/ahliterature299192
Source
BMC Public Health. 2018 05 02; 18(1):565
Publication Type
Journal Article
Date
05-02-2018
Author
Taina Rantanen
Milla Saajanaho
Laura Karavirta
Sini Siltanen
Merja Rantakokko
Anne Viljanen
Timo Rantalainen
Katja Pynnönen
Anu Karvonen
Inna Lisko
Lotta Palmberg
Johanna Eronen
Eeva-Maija Palonen
Timo Hinrichs
Markku Kauppinen
Katja Kokko
Erja Portegijs
Author Affiliation
Gerontology Research Center, Faculty of Sport and Health Sciences, Univerisity of Jyvaskyla, P.O. Box 35 (viv 149), 40014, Jyväskylä, Finland. taina.rantanen@jyu.fi.
Source
BMC Public Health. 2018 05 02; 18(1):565
Date
05-02-2018
Language
English
Publication Type
Journal Article
Keywords
Aged
Aged, 80 and over
Aging - psychology
Cohort Studies
Disabled persons - statistics & numerical data
Exercise
Female
Finland
Health Behavior
Health Literacy
Humans
Male
Resilience, Psychological
Social Support
Abstract
Population aging increases the need for knowledge on positive aspects of aging, and contributions of older people to their own wellbeing and that of others. We defined active aging as an individual's striving for elements of wellbeing with activities as per their goals, abilities and opportunities. This study examines associations of health, health behaviors, health literacy and functional abilities, environmental and social support with active aging and wellbeing. We will develop and validate assessment methods for physical activity and physical resilience suitable for research on older people, and examine their associations with active aging and wellbeing. We will examine cohort effects on functional phenotypes underlying active aging and disability.
For this population-based study, we plan to recruit 1000 participants aged 75, 80 or 85 years living in central Finland, by drawing personal details from the population register. Participants are interviewed on active aging, wellbeing, disability, environmental and social support, mobility, health behavior and health literacy. Physical activity and heart rate are monitored for 7 days with wearable sensors. Functional tests include hearing, vision, muscle strength, reaction time, exercise tolerance, mobility, and cognitive performance. Clinical examination by a nurse and physician includes an electrocardiogram, tests of blood pressure, orthostatic regulation, arterial stiffness, and lung function, as well as a review of chronic and acute conditions and prescribed medications. C-reactive protein, small blood count, cholesterol and vitamin D are analyzed from blood samples. Associations of factors potentially underlying active aging and wellbeing will be studied using multivariate methods. Cohort effects will be studied by comparing test results of physical and cognitive functioning with results of a cohort examined in 1989-90.
The current study will renew research on positive gerontology through the novel approach to active aging and by suggesting new biomarkers of resilience and active aging. Therefore, high interdisciplinary impact is expected. This cross-sectional study will not provide knowledge on temporal order of events or causality, but an innovative cross-sectional dataset provides opportunities for emergence of novel creative hypotheses and theories.
PubMed ID
29716566 View in PubMed
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Barriers to outdoor physical activity and unmet physical activity need in older adults.

https://arctichealth.org/en/permalink/ahliterature266937
Source
Prev Med. 2014 Oct;67:106-11
Publication Type
Article
Date
Oct-2014
Author
Johanna Eronen
Mikaela B von Bonsdorff
Timo Törmäkangas
Merja Rantakokko
Erja Portegijs
Anne Viljanen
Taina Rantanen
Source
Prev Med. 2014 Oct;67:106-11
Date
Oct-2014
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Aging
Cohort Studies
Cross-Sectional Studies
Environment
Environment Design
Exercise
Female
Finland
Geriatric Assessment
Health status
Humans
Male
Mobility Limitation
Questionnaires
Walking
Abstract
To profile participants based on reported outdoor physical activity barriers using a data-driven approach, describe the profiles and study their association with unmet physical activity need.
Cross-sectional analyses of 848 community-dwelling men and women aged 75-90 living in Central Finland in 2012. Barriers to outdoor physical activity and unmet physical activity need were enquired with a questionnaire. The latent profiles were identified by profiling participants into latent groups using a mixture modeling technique on the multivariate set of indicators of outdoor physical activity barriers. A path model was used to study the associations of the profiles with unmet physical activity need.
Five barrier profiles were identified. Profile A was characterized with minor barriers, profile B with weather barriers, profile C with health and weather barriers, profile D with barriers concerning insecurity, health and weather; and profile E with mobility and health barriers. The participants in the profiles differed in the proportion of individual and environmental barriers. The risk for unmet physical activity need was highest among people whose severe mobility difficulties restricted their outdoor physical activity.
Outdoor physical activity barriers reflect the imbalance in person-environment fit among older people, manifested as unmet physical activity need.
PubMed ID
25045839 View in PubMed
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Body fat and mobility are explained by common genetic and environmental influences in older women.

https://arctichealth.org/en/permalink/ahliterature157662
Source
Obesity (Silver Spring). 2008 Jul;16(7):1616-21
Publication Type
Article
Date
Jul-2008
Author
Alfredo Ortega-Alonso
Sarianna Sipilä
Urho M Kujala
Jaakko Kaprio
Taina Rantanen
Author Affiliation
Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland. alfredo.ortega@sport.jyu.fi
Source
Obesity (Silver Spring). 2008 Jul;16(7):1616-21
Date
Jul-2008
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Adiposity - genetics
Age Factors
Aged
Aging - genetics
Electric Impedance
Environment
Female
Finland
Genetic Predisposition to Disease
Humans
Locomotion - genetics
Middle Aged
Mobility Limitation
Models, Genetic
Obesity - genetics - physiopathology
Physical Endurance - genetics
Risk factors
Twins, Dizygotic - genetics
Twins, Monozygotic - genetics
Walking
Abstract
In older adults, mobility limitations often coexist with overweight or obesity, suggesting that similar factors may underlie both traits. This study examined the extent to which genetic and environmental influences explain the association between adiposity and mobility in older women. Body fat percentage (bioimpedance test), walking speed over 10 m, and distance walked in a 6-min test were evaluated in 92 monozygotic (MZ) and 104 dizygotic (DZ) pairs of twin sisters reared together, aged 63-76 years. Genetic and environmental influences on each trait were estimated using age-adjusted multivariate genetic modeling. The analyses showed that the means (and s.d.) for body fat percentage, walking speed, and walking endurance were 33.2+/-7.3%, 1.7+/-0.3 m/s and 529.7+/-75.4 m, respectively. The phenotypic correlation between adiposity and walking speed was -0.32 and between adiposity and endurance it was -0.33. Genetic influences explained 80% of the association between adiposity and speed, and 65% of adiposity and walking endurance. Cross-trait genetic influences accounted for 12% of the variability in adiposity, 56% in walking speed, and 34% in endurance. Trait-specific genetic influences were also detected for adiposity (54%) and walking endurance (13%), but not speed. In conclusion, among community-living older women, an inverse association was found between adiposity and mobility that was mostly due to the effect of shared genes. This result suggests that the identification of genetic variants for body fat metabolism may also provide understanding of the development of mobility limitations in older women.
PubMed ID
18421266 View in PubMed
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Changes in residential proximity to road traffic and the risk of death from coronary heart disease.

https://arctichealth.org/en/permalink/ahliterature142555
Source
Epidemiology. 2010 Sep;21(5):642-9
Publication Type
Article
Date
Sep-2010
Author
Wen Qi Gan
Lillian Tamburic
Hugh W Davies
Paul A Demers
Mieke Koehoorn
Michael Brauer
Author Affiliation
School of Environmental Health, The University of British Columbia, Vancouver, BC, Canada.
Source
Epidemiology. 2010 Sep;21(5):642-9
Date
Sep-2010
Language
English
Publication Type
Article
Keywords
Age Factors
Aged
Aged, 80 and over
Air Pollution - adverse effects
British Columbia - epidemiology
Cohort Studies
Coronary Disease - etiology - mortality
Dibutyl Phthalate
Environmental Exposure - adverse effects
Female
Humans
Logistic Models
Male
Middle Aged
Motor Vehicles - statistics & numerical data
Risk factors
Sex Factors
Socioeconomic Factors
Abstract
Residential proximity to road traffic is associated with increased coronary heart disease (CHD) morbidity and mortality. It is unknown, however, whether changes in residential proximity to traffic could alter the risk of CHD mortality.
We used a population-based cohort study with a 5-year exposure period and a 4-year follow-up period to explore the association between changes in residential proximity to road traffic and the risk of CHD mortality. The cohort comprised all residents aged 45-85 years who resided in metropolitan Vancouver during the exposure period and without known CHD at baseline (n = 450,283). Residential proximity to traffic was estimated using a geographic information system. CHD deaths during the follow-up period were identified using provincial death registration database. The data were analyzed using logistic regression.
Compared with the subjects consistently living away from road traffic (>150 m from a highway or >50 m from a major road) during the 9-year study period, those consistently living close to traffic (
PubMed ID
20585255 View in PubMed
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Descriptive epidemiological features of bronchiolitis in a population-based cohort.

https://arctichealth.org/en/permalink/ahliterature153946
Source
Pediatrics. 2008 Dec;122(6):1196-203
Publication Type
Article
Date
Dec-2008
Author
Mieke Koehoorn
Catherine J Karr
Paul A Demers
Cornel Lencar
Lillian Tamburic
Michael Brauer
Author Affiliation
School of Environmental Health, Centre for Health Services and Policy Research, University of British Columbia, 5804 Fairview Ave, Vancouver, British Columbia, Canada V6T 1Z3. mieke.koehoorn@ubc.ca
Source
Pediatrics. 2008 Dec;122(6):1196-203
Date
Dec-2008
Language
English
Publication Type
Article
Keywords
Age Distribution
Breast Feeding
British Columbia - epidemiology
Bronchiolitis - diagnosis - epidemiology
Cohort Studies
Female
Hospitalization - statistics & numerical data
Humans
Incidence
Infant
Male
Multivariate Analysis
Prognosis
Proportional Hazards Models
Retrospective Studies
Risk assessment
Severity of Illness Index
Sex Distribution
Tobacco Smoke Pollution - statistics & numerical data
Abstract
The goal was to investigate the epidemiological features of incident bronchiolitis by using a population-based infant cohort.
Outpatient and inpatient health records were used to identify incident bronchiolitis cases among 93,058 singleton infants born in the Georgia Air Basin between 1999 and 2002. Additional health-related databases were linked to provide data on sociodemographic variables, maternal characteristics, and birth outcome measures.
From 1999 to 2002, bronchiolitis accounted for 12,474 incident health care encounters (inpatient or outpatient contacts) during the first year of life (134.2 cases per 1000 person-years). A total of 1588 hospitalized bronchiolitis cases were identified (17.1 cases per 1000 person-years). Adjusted Cox proportional-hazard analyses for both case definitions indicated an increased risk of incident bronchiolitis in the first year of life (follow-up period: 2-12 months) for boys, infants of First Nations status, infants with older siblings, and infants living in neighborhoods with smaller proportions of maternal postsecondary education. The risk also was elevated for infants born to young mothers (
PubMed ID
19047234 View in PubMed
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Determinants of plasma PCB, brominated flame retardants, and organochlorine pesticides in pregnant women and 3 year old children in The Norwegian Mother and Child Cohort Study.

https://arctichealth.org/en/permalink/ahliterature273849
Source
Environ Res. 2016 Apr;146:136-44
Publication Type
Article
Date
Apr-2016
Author
Ida Henriette Caspersen
Helen Engelstad Kvalem
Margaretha Haugen
Anne Lise Brantsæter
Helle Margrete Meltzer
Jan Alexander
Cathrine Thomsen
May Frøshaug
Nanna Margrethe Bruun Bremnes
Sharon Lynn Broadwell
Berit Granum
Manolis Kogevinas
Helle Katrine Knutsen
Source
Environ Res. 2016 Apr;146:136-44
Date
Apr-2016
Language
English
Publication Type
Article
Keywords
Child, Preschool
Cohort Studies
Demography
Diet
Environmental Exposure
Environmental monitoring
Environmental pollutants - blood
Female
Flame Retardants - metabolism
Humans
Hydrocarbons, Brominated - blood
Hydrocarbons, Chlorinated - blood
Life Style
Norway
Pesticides - blood
Polybrominated Biphenyls - blood
Polychlorinated biphenyls - blood
Pregnancy
Abstract
Exposure to persistent organic pollutants (POPs) during prenatal and postnatal life has been extensively studied in relation to adverse health effects in children.
The aim was to identify determinants of the concentrations of polychlorinated biphenyls (PCBs), brominated flame retardants (polybrominated diphenyl ethers, PBDEs; polybrominated biphenyl, PBB), and organochlorine pesticides (OCPs) in blood samples from pregnant women and children in The Norwegian Mother and Child Cohort Study (MoBa).
Blood samples were collected from two independent subsamples within MoBa; a group of women (n=96) enrolled in mid-pregnancy during the years 2002-2008 and a group of 3 year old children (n=99) participating during 2010-2011. PCB congeners (74, 99, 138, 153, 180, 170, 194, 209, 105, 114, 118, 156, 157, 167, and 189), brominated flame retardants (PBDE-28, 47, 99, 100, 153, 154, and PBB-153), as well as the OCPs hexachlorobenzene (HCB), oxychlordane, 4,4'dichlorodiphenyltrichloroethane (DDT), and 4,4'dichlorodiphenyldichloroethylene (DDE) were measured in both pregnant women and children.
Age, low parity, and low pre-pregnant BMI were the most important determinants of increased plasma concentrations of POPs in pregnant women. In 3 year old children, prolonged breastfeeding duration was a major determinant of increased POP concentrations. Estimated dietary exposure to PCBs during pregnancy was positively associated with plasma concentrations in 3 year old children, but not in pregnant women. Plasma concentrations were approximately 40% higher in children compared to pregnant women.
Several factors associated with exposure and toxicokinetics, i.e. accumulation, excretion and transfer via breastmilk of POPs were the main predictors of POP levels in pregnant women and children. Diet, which is the main exposure source for these compounds in the general population, was found to predict PCB levels only among children. For the PBDEs, for which non-dietary sources are more important, toxicokinetic factors appeared to have less predictive impact.
PubMed ID
26749444 View in PubMed
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Dietary acrylamide intake during pregnancy and fetal growth-results from the Norwegian mother and child cohort study (MoBa).

https://arctichealth.org/en/permalink/ahliterature118477
Source
Environ Health Perspect. 2013 Mar;121(3):374-9
Publication Type
Article
Date
Mar-2013
Author
Talita Duarte-Salles
Hans von Stedingk
Berit Granum
Kristine B Gützkow
Per Rydberg
Margareta Törnqvist
Michelle A Mendez
Gunnar Brunborg
Anne Lise Brantsæter
Helle Margrete Meltzer
Jan Alexander
Margaretha Haugen
Author Affiliation
Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway.
Source
Environ Health Perspect. 2013 Mar;121(3):374-9
Date
Mar-2013
Language
English
Publication Type
Article
Keywords
Acrylamide - administration & dosage - pharmacology
Cohort Studies
Diet
Environmental Exposure
Female
Fetal Development - drug effects
Hemoglobins - chemistry
Humans
Norway
Pregnancy
Questionnaires
Abstract
Acrylamide has shown developmental and reproductive toxicity in animals, as well as neurotoxic effects in humans with occupational exposures. Because it is widespread in food and can pass through the human placenta, concerns have been raised about potential developmental effects of dietary exposures in humans.
We assessed associations of prenatal exposure to dietary acrylamide with small for gestational age (SGA) and birth weight.
This study included 50,651 women in the Norwegian Mother and Child Cohort Study (MoBa). Acrylamide exposure assessment was based on intake estimates obtained from a food frequency questionnaire (FFQ), which were compared with hemoglobin (Hb) adduct measurements reflecting acrylamide exposure in a subset of samples (n = 79). Data on infant birth weight and gestational age were obtained from the Medical Birth Registry of Norway. Multivariable regression was used to estimate associations between prenatal acrylamide and birth outcomes.
Acrylamide intake during pregnancy was negatively associated with fetal growth. When women in the highest quartile of acrylamide intake were compared with women in the lowest quartile, the multivariable-adjusted odds ratio (OR) for SGA was 1.11 (95% CI: 1.02, 1.21) and the coefficient for birth weight was -25.7 g (95% CI: -35.9, -15.4). Results were similar after excluding mothers who smoked during pregnancy. Maternal acrylamide- and glycidamide-Hb adduct levels were correlated with estimated dietary acrylamide intakes (Spearman correlations = 0.24; 95% CI: 0.02, 0.44; and 0.48; 95% CI: 0.29, 0.63, respectively).
Lowering dietary acrylamide intake during pregnancy may improve fetal growth.
Notes
Cites: Scand J Work Environ Health. 2001 Aug;27(4):219-2611560335
Cites: Paediatr Perinat Epidemiol. 2009 Nov;23(6):597-60819840297
Cites: Trends Endocrinol Metab. 2002 Nov;13(9):364-812367816
Cites: Chemotherapy. 2002;48(6):267-7412673101
Cites: Toxicol Sci. 2003 Sep;75(1):7-1512805639
Cites: Int Arch Occup Environ Health. 2004 Apr;77(3):213-614740221
Cites: IARC Monogr Eval Carcinog Risks Hum. 1994;60:389-4337869577
Cites: Chem Res Toxicol. 1997 Jan;10(1):78-849074806
Cites: Mutat Res. 2005 Feb 7;580(1-2):3-2015668103
Cites: Food Chem Toxicol. 2005 Mar;43(3):365-41015680675
Cites: Birth Defects Res B Dev Reprod Toxicol. 2005 Feb;74(1):17-11315729727
Cites: Crit Rev Toxicol. 2006 Jul-Aug;36(6-7):481-60816973444
Cites: Int J Epidemiol. 2006 Oct;35(5):1146-5016926217
Cites: Toxicol Sci. 2007 Jul;98(1):110-717449897
Cites: Matern Child Nutr. 2008 Jan;4(1):14-2718171404
Cites: J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Oct 1;878(27):2483-9020399714
Cites: Food Chem Toxicol. 2011 Aug;49(8):1843-821571030
Cites: Int J Epidemiol. 2011 Jun;40(3):647-6121324938
Cites: Chem Res Toxicol. 2011 Nov 21;24(11):1957-6521882862
Cites: Int J Hyg Environ Health. 2012 Feb;215(2):216-921937271
Cites: Food Chem Toxicol. 2012 Jul;50(7):2531-922525869
Cites: Environ Health Perspect. 2012 Dec;120(12):1739-4523092936
Cites: Food Chem Toxicol. 2010 Nov;48(11):3098-10820696196
Cites: Nutrition. 2011 Mar;27(3):343-5021329872
Cites: Am J Clin Nutr. 2000 May;71(5 Suppl):1344S-52S10799412
Cites: Acta Obstet Gynecol Scand. 2000 Jun;79(6):435-910857866
Cites: Acta Obstet Gynecol Scand. 2000 Jun;79(6):440-910857867
Cites: Chem Res Toxicol. 2000 Jun;13(6):517-2210858325
Cites: Semin Neonatol. 2000 Aug;5(3):231-4110956448
Cites: Matern Child Nutr. 2008 Jan;4(1):28-4318171405
Cites: Eur J Clin Nutr. 2008 Mar;62(3):314-2317356560
Cites: Cancer Causes Control. 2008 Apr;19(3):273-8117985202
Cites: Mutat Res. 2008 May 31;653(1-2):50-618485803
Cites: Food Chem Toxicol. 2008 Aug;46(8):2808-1418599176
Cites: Toxicol Lett. 2008 Nov 10;182(1-3):50-618790027
Cites: Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):5-1019124475
Cites: Toxicol Sci. 2009 Mar;108(1):90-919131562
Cites: Am J Clin Nutr. 2009 Mar;89(3):773-719158207
Cites: Cancer Causes Control. 2009 Apr;20(3):269-7818855107
Cites: Int J Cancer. 2009 May 15;124(10):2384-9019142870
Cites: J Agric Food Chem. 2002 Aug 14;50(17):4998-500612166997
PubMed ID
23204292 View in PubMed
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Dietary benzo(a)pyrene intake during pregnancy and birth weight: associations modified by vitamin C intakes in the Norwegian Mother and Child Cohort Study (MoBa).

https://arctichealth.org/en/permalink/ahliterature107027
Source
Environ Int. 2013 Oct;60:217-23
Publication Type
Article
Date
Oct-2013
Author
Talita Duarte-Salles
Michelle A Mendez
Helle Margrete Meltzer
Jan Alexander
Margaretha Haugen
Author Affiliation
Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway. Electronic address: duartesallest@fellows.iarc.fr.
Source
Environ Int. 2013 Oct;60:217-23
Date
Oct-2013
Language
English
Publication Type
Article
Keywords
Adult
Ascorbic Acid - pharmacology
Benzo(a)pyrene - administration & dosage - analysis - toxicity
Birth Weight - drug effects
Child
Cohort Studies
Diet - statistics & numerical data
Female
Fetal Development - drug effects
Food - classification
Food Contamination - analysis - statistics & numerical data
Heredodegenerative Disorders, Nervous System - chemically induced
Humans
Infant
Maternal Exposure - statistics & numerical data
Microphthalmos - chemically induced
Multivariate Analysis
Mutagenicity Tests
Norway - epidemiology
Parity
Polycyclic Hydrocarbons, Aromatic - toxicity
Pregnancy
Pregnancy Outcome - epidemiology
Prenatal Exposure Delayed Effects - epidemiology
Abstract
Maternal exposure to polycyclic aromatic hydrocarbons (PAH) during pregnancy has been associated with reduced fetal growth. However, the role of diet, the main source of PAH exposure among non-smokers, remains uncertain.
To assess associations between maternal exposure to dietary intake of the genotoxic PAH benzo(a)pyrene [B(a)P] during pregnancy and birth weight, exploring potential effect modification by dietary intakes of vitamins C, E and A, hypothesized to influence PAH metabolism.
This study included 50,651 women in the Norwegian Mother and Child Cohort Study (MoBa). Dietary B(a)P and nutrient intakes were estimated based on total consumption obtained from a food frequency questionnaire (FFQ) and estimated based on food composition data. Data on infant birth weight were obtained from the Medical Birth Registry of Norway (MBRN). Multivariate regression was used to assess associations between dietary B(a)P and birth weight, evaluating potential interactions with candidate nutrients.
The multivariate-adjusted coefficient (95%CI) for birth weight associated with maternal energy-adjusted B(a)P intake was -20.5g (-31.1, -10.0) in women in the third compared with the first tertile of B(a)P intake. Results were similar after excluding smokers. Significant interactions were found between elevated intakes of vitamin C (>85mg/day) and dietary B(a)P during pregnancy for birth weight (P
PubMed ID
24071023 View in PubMed
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Dietary exposure to dioxins and PCBs in a large cohort of pregnant women: results from the Norwegian Mother and Child Cohort Study (MoBa).

https://arctichealth.org/en/permalink/ahliterature108262
Source
Environ Int. 2013 Sep;59:398-407
Publication Type
Article
Date
Sep-2013
Author
Ida H Caspersen
Helle K Knutsen
Anne Lise Brantsæter
Margaretha Haugen
Jan Alexander
Helle Margrete Meltzer
Helen E Kvalem
Author Affiliation
Norwegian Institute of Public Health, Oslo, Norway. ida.henriette.caspersen@fhi.no
Source
Environ Int. 2013 Sep;59:398-407
Date
Sep-2013
Language
English
Publication Type
Article
Keywords
Adult
Body Burden
Cohort Studies
Diet - adverse effects
Dioxins - administration & dosage - blood
Environmental Exposure
Environmental Pollutants - administration & dosage - analysis - blood
Female
Fish Products - adverse effects - analysis
Food Contamination
Humans
Norway
Polychlorinated Biphenyls - administration & dosage - blood
Tetrachlorodibenzodioxin - blood
Young Adult
Abstract
Exposure to dioxins and polychlorinated biphenyls (PCBs) during pregnancy and breastfeeding may result in adverse health effects in children. Prenatal exposure is determined by the concentrations of dioxins and PCBs in maternal blood, which reflect the body burden obtained by long term dietary exposure. The aims of this study were (1) to describe dietary exposure and important dietary sources to dioxins and PCBs in a large group of pregnant women and (2) to identify maternal characteristics associated with high dietary exposure to dioxins and PCBs. Dietary exposure to dioxins (sum of toxic equivalents (TEQs) from dioxin-like (dl) compounds) and PCB-153 in 83,524 pregnant women (gestational weeks 17-22) who participated in the Norwegian Mother and Child Cohort Study (MoBa) during the years 2002-2009 was calculated based on a food frequency questionnaire (FFQ) and a database of dioxin and PCB concentrations in Norwegian food. The median (interquartile range, IQR) intake of PCB-153 (marker of ndl-PCBs) was 0.81 (0.77) ng/kg bw/day. For dioxins and dioxin-like PCBs, the median (IQR) intake was 0.56 (0.37) pg TEQ/kg bw/day. Moreover, 2.3% of the participants had intakes exceeding the tolerable weekly intake (TWI) of 14pg TEQ/kg bw/week. Multiple regression analysis showed that dietary exposure was positively associated with maternal age, maternal education, weight gain during pregnancy, being a student, and alcohol consumption during pregnancy and negatively associated with pre-pregnancy BMI and smoking. A high dietary exposure to PCB-153 or dl-compounds (TEQ) was mainly explained by the consumption of seagull eggs and/or pate with fish liver and roe. Women who according to Norwegian recommendations avoid these food items generally do not have dietary exposure above the tolerable intake of dioxins and dl-PCBs.
PubMed ID
23911340 View in PubMed
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Do Associations Between Perceived Environmental and Individual Characteristics and Walking Limitations Depend on Lower Extremity Performance Level?

https://arctichealth.org/en/permalink/ahliterature291084
Source
J Aging Health. 2017 Jun; 29(4):640-656
Publication Type
Comparative Study
Journal Article
Date
Jun-2017
Author
Ritva Sakari
Merja Rantakokko
Erja Portegijs
Susanne Iwarsson
Sarianna Sipilä
Anne Viljanen
Taina Rantanen
Author Affiliation
1 University of Jyvaskyla, Finland.
Source
J Aging Health. 2017 Jun; 29(4):640-656
Date
Jun-2017
Language
English
Publication Type
Comparative Study
Journal Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Cross-Sectional Studies
Disability Evaluation
Environment
Female
Geriatric Assessment - methods
Humans
Independent living
Interviews as Topic
Lower Extremity - physiopathology
Male
Mobility Limitation
Perception
Physical Fitness - physiology
Sweden
Task Performance and Analysis
Walking - physiology
Abstract
The aim of this study was to analyze whether the associations between perceived environmental and individual characteristics and perceived walking limitations in older people differ between those with intact and those with poorer lower extremity performance.
Persons aged 75 to 90 ( N = 834) participated in interviews and performance tests in their homes. Standard questionnaires were used to obtain walking difficulties; environmental barriers to and, facilitators of, mobility; and perceived individual hindrances to outdoor mobility. Lower extremity performance was tested using Short Physical Performance Battery (SPPB).
Among those with poorer lower extremity performance, the likelihood for advanced walking limitations was, in particular, related to perceived poor safety in the environment, and among those with intact performance to perceived social issues, such as lack of company, as well as to long distances.
The environmental correlates of walking limitations seem to depend on the level of lower extremity performance.
PubMed ID
27056910 View in PubMed
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Effect of dietary factors in pregnancy on risk of pregnancy complications: results from the Norwegian Mother and Child Cohort Study.

https://arctichealth.org/en/permalink/ahliterature134772
Source
Am J Clin Nutr. 2011 Dec;94(6 Suppl):1970S-1974S
Publication Type
Article
Date
Dec-2011
Author
Helle Margrete Meltzer
Anne Lise Brantsæter
Roy M Nilsen
Per Magnus
Jan Alexander
Margareta Haugen
Author Affiliation
Divisions of Environmental Medicine and Epidemiology, Norwegian Institute of Public Health, Oslo, Norway. helle.margrete.meltzer@fhi.no
Source
Am J Clin Nutr. 2011 Dec;94(6 Suppl):1970S-1974S
Date
Dec-2011
Language
English
Publication Type
Article
Keywords
Birth weight
Diet, Mediterranean
European Continental Ancestry Group
Female
Folic Acid - administration & dosage
Food Habits
Humans
Norway - epidemiology
Nutrition Assessment
Nutritional Status
Pre-Eclampsia - epidemiology - etiology - pathology
Pregnancy
Pregnancy Complications - epidemiology - etiology
Premature Birth - metabolism
Prospective Studies
Questionnaires
Risk factors
Vitamin D - administration & dosage
Abstract
There has been a thrilling development , as well as profound changes, in our understanding of the effect of fetal nutrition on the development and health of the child. The Norwegian Mother and Child Cohort Study (MoBa) is an ongoing nationwide population-based pregnancy cohort study that between 1999 and 2008 recruited 90,723 women with 106,981 pregnancies and 108,487 children. The objective of MoBa is to test specific etiologic hypotheses by estimating the association between exposures and diseases with a special focus on disorders that may originate in early life. An important aspect in this regard is maternal diet and nutritional status during pregnancy. Nutritional factors have long been considered to be important determinants of maternal and fetal health, and dietary information is currently being collected in a number of pregnancy cohorts in Europe and the United States. Thus far, pregnancy complications studied in MoBa are preterm birth, preeclampsia, and fetal growth; and the aim of this article is to report results of recently published studies of dietary factors in relation to these outcomes. Numerous studies are planned using MoBa data, and the aim is to add to the knowledge of the interplay between dietary factors, nonnutrients, and toxic dietary substances and epigenetic modulation on fetal development and health later in life.
Notes
Cites: J Clin Endocrinol Metab. 2007 Sep;92(9):3517-2217535985
Cites: Am J Obstet Gynecol. 2001 Aug;185(2):451-811518908
Cites: Matern Child Nutr. 2008 Jan;4(1):14-2718171404
Cites: Matern Child Nutr. 2008 Jan;4(1):28-4318171405
Cites: Environ Health. 2007;6:3317958907
Cites: Acta Obstet Gynecol Scand. 2008;87(3):319-2418307072
Cites: Arch Dis Child. 2009 Mar;94(3):180-419052032
Cites: Eur J Clin Nutr. 2009 Mar;63(3):347-5418059417
Cites: J Nutr. 2009 Jun;139(6):1162-819369368
Cites: Epidemiology. 2009 Sep;20(5):720-619451820
Cites: Am J Epidemiol. 2009 Dec 15;170(12):1486-9319880541
Cites: Public Health Nutr. 2010 Jan;13(1):54-6219490733
Cites: Acta Obstet Gynecol Scand. 2000 Jun;79(6):435-910857866
Cites: Public Health Nutr. 2001 Apr;4(2B):611-2411683554
Cites: Environ Health Perspect. 2003 Apr;111(4):637-4112676628
Cites: J Nutr. 2003 May;133(5 Suppl 2):1684S-1692S12730485
Cites: J Soc Gynecol Investig. 2004 Jul;11(5):263-7115219879
Cites: Nutr Rev. 1994 Mar;52(3):84-948015751
Cites: Am J Clin Nutr. 1995 Jun;61(6 Suppl):1402S-1406S7754995
Cites: Reprod Fertil Dev. 2005;17(3):341-815745642
Cites: Am J Obstet Gynecol. 2005 Oct;193(4):1292-30116202717
Cites: JAMA. 2006 Oct 18;296(15):1885-9917047219
Cites: Int J Epidemiol. 2006 Oct;35(5):1146-5016926217
Cites: Eur J Epidemiol. 2006;21(10):749-5817111251
Cites: Ann Nutr Metab. 2007;51(2):146-5417536192
Cites: Public Health Nutr. 2007 Aug;10(8):838-4717493318
Cites: Ann Epidemiol. 2007 Sep;17(9):663-817521921
Cites: Am J Epidemiol. 2007 Sep 15;166(6):687-9617631607
Cites: J Nutr. 2010 Mar;140(3):572-920089778
Cites: Environ Int. 2007 Nov;33(8):1057-6217643489
PubMed ID
21543541 View in PubMed
Less detail

Effect of early life exposure to air pollution on development of childhood asthma.

https://arctichealth.org/en/permalink/ahliterature145670
Source
Environ Health Perspect. 2010 Feb;118(2):284-90
Publication Type
Article
Date
Feb-2010
Author
Nina Annika Clark
Paul A Demers
Catherine J Karr
Mieke Koehoorn
Cornel Lencar
Lillian Tamburic
Michael Brauer
Author Affiliation
School of Population and Public Health, University of British Columbia, British Columbia, Canada.
Source
Environ Health Perspect. 2010 Feb;118(2):284-90
Date
Feb-2010
Language
English
Publication Type
Article
Keywords
Air Pollution - adverse effects
Asthma - chemically induced
British Columbia
Carbon Monoxide - adverse effects
Case-Control Studies
Child, Preschool
Environmental Exposure - adverse effects
Female
Humans
Logistic Models
Male
Nitrogen Dioxide - adverse effects
Nitrogen Oxides - adverse effects
Particulate Matter - adverse effects
Pregnancy
Prenatal Exposure Delayed Effects - chemically induced
Time Factors
United States
Abstract
There is increasing recognition of the importance of early environmental exposures in the development of childhood asthma. Outdoor air pollution is a recognized asthma trigger, but it is unclear whether exposure influences incident disease. We investigated the effect of exposure to ambient air pollution in utero and during the first year of life on risk of subsequent asthma diagnosis in a population-based nested case-control study.
We assessed all children born in southwestern British Columbia in 1999 and 2000 (n = 37,401) for incidence of asthma diagnosis up to 34 years of age using outpatient and hospitalization records. Asthma cases were age- and sex-matched to five randomly chosen controls from the eligible cohort. We estimated each individual's exposure to ambient air pollution for the gestational period and first year of life using high-resolution pollution surfaces derived from regulatory monitoring data as well as land use regression models adjusted for temporal variation. We used logistic regression analyses to estimate effects of carbon monoxide, nitric oxide, nitrogen dioxide, particulate matter
Notes
Cites: J Allergy Clin Immunol. 2000 Jan;105(1 Pt 1):9-1910629447
Cites: Environ Sci Technol. 2009 Jul 1;43(13):4701-619673254
Cites: Epidemiology. 2000 Sep;11(5):502-1110955401
Cites: Eur Respir J. 2002 Apr;19(4):690-811998999
Cites: J Toxicol Environ Health B Crit Rev. 2002 Jul-Sep;5(3):269-8212162869
Cites: Am J Respir Crit Care Med. 2002 Oct 15;166(8):1092-812379553
Cites: Epidemiology. 2003 Mar;14(2):228-3912606891
Cites: Eur Respir J. 2003 Jun;21(6):956-6312797488
Cites: Am J Epidemiol. 2003 Oct 1;158(7):705-914507607
Cites: J Epidemiol Community Health. 2004 Jan;58(1):18-2314684722
Cites: Chest. 2004 Oct;126(4):1071-815486366
Cites: Chest. 2004 Oct;126(4):1147-5315486376
Cites: BMJ. 1993 Sep 4;307(6904):596-6007691304
Cites: N Engl J Med. 1995 Jan 19;332(3):133-87800004
Cites: Environ Health Perspect. 1997 Feb;105(2):216-229105797
Cites: Environ Res. 1997;74(2):122-329339225
Cites: Environ Health Perspect. 1998 Jun;106(6):325-99618348
Cites: Occup Environ Med. 1998 Nov;55(11):771-89924455
Cites: Am J Respir Crit Care Med. 1999 Mar;159(3):768-7510051249
Cites: Environ Health Perspect. 1999 Jun;107(6):489-9310339450
Cites: Environ Health Perspect. 1999 Sep;107(9):757-6010464077
Cites: Environ Health Perspect. 1999 Sep;107(9):761-710464078
Cites: Environ Health Perspect. 2005 Mar;113(3):357-6115743728
Cites: J Expo Anal Environ Epidemiol. 2005 Mar;15(2):185-20415292906
Cites: Epidemiology. 2005 Nov;16(6):737-4316222162
Cites: Environ Health Perspect. 2005 Nov;113(11):1638-4416263524
Cites: Pediatr Allergy Immunol. 2006 Feb;17(1):69-7616426258
Cites: Environ Health Perspect. 2006 May;114(5):766-7216675435
Cites: Lancet. 2006 Aug 26;368(9537):733-4316935684
Cites: Occup Environ Med. 2007 Jan;64(1):8-1616912084
Cites: Environ Sci Technol. 2007 Apr 1;41(7):2422-817438795
Cites: Environ Sci Technol. 2007 Apr 1;41(7):2429-3617438796
Cites: Eur Respir J. 2007 May;29(5):879-8817251230
Cites: Am J Epidemiol. 2007 Sep 15;166(6):679-8617625224
Cites: Environ Health Perspect. 2007 Sep;115(9):1283-9217805417
Cites: Birth Defects Res C Embryo Today. 2007 Sep;81(3):144-5417963272
Cites: Arch Pediatr Adolesc Med. 2007 Dec;161(12):1197-20418056566
Cites: Inhal Toxicol. 2008 Feb;20(4):423-3318302050
Cites: Epidemiology. 2008 May;19(3):401-818379426
Cites: BMC Health Serv Res. 2008;8:7918402681
Cites: Environ Health Perspect. 2008 May;116(5):680-618470315
Cites: Am J Respir Crit Care Med. 2008 Jun 15;177(12):1331-718337595
Cites: Epidemiology. 2008 Jul;19(4):550-7; discussion 561-218520616
Cites: Environ Health Perspect. 2000 Feb;108(2):173-610656859
Comment In: Environ Health Perspect. 2010 Feb;118(2):A8020123625
Comment In: Environ Health Perspect. 2010 Jul;118(7):A283-420601332Camatini, Marina [removed]; Bolzacchini, Ezio [removed]
PubMed ID
20123607 View in PubMed
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Environmental barriers, person-environment fit and mortality among community-dwelling very old people.

https://arctichealth.org/en/permalink/ahliterature265500
Source
BMC Public Health. 2013;13:783
Publication Type
Article
Date
2013
Author
Merja Rantakokko
Timo Törmäkangas
Taina Rantanen
Maria Haak
Susanne Iwarsson
Source
BMC Public Health. 2013;13:783
Date
2013
Language
English
Publication Type
Article
Keywords
Aged, 80 and over
Architectural Accessibility
Environment
Female
Frail Elderly
Housing for the Elderly
Humans
Male
Mobility Limitation
Mortality - trends
Proportional Hazards Models
Sweden - epidemiology
Abstract
Environmental barriers are associated with disability-related outcomes in older people but little is known of the effect of environmental barriers on mortality. The aim of this study was to examine whether objectively measured barriers in the outdoor, entrance and indoor environments are associated with mortality among community-dwelling 80- to 89-year-old single-living people.
This longitudinal study is based on a sample of 397 people who were single-living in ordinary housing in Sweden. Participants were interviewed during 2002-2003, and 393 were followed up for mortality until May 15, 2012.Environmental barriers and functional limitations were assessed with the Housing Enabler instrument, which is intended for objective assessments of Person-Environment (P-E) fit problems in housing and the immediate outdoor environment. Mortality data were gathered from the public national register. Cox regression models were used for the analyses.
A total of 264 (67%) participants died during follow-up. Functional limitations increased mortality risk. Among the specific environmental barriers that generate the most P-E fit problems, lack of handrails in stairs at entrances was associated with the highest mortality risk (adjusted RR 1.55, 95% CI 1.14-2.10), whereas the total number of environmental barriers at entrances and outdoors was not associated with mortality. A higher number of environmental barriers indoors showed a slight protective effect against mortality even after adjustment for functional limitations (RR 0.98, 95% CI 0.96-1.00).
Specific environmental problems may increase mortality risk among very-old single-living people. However, the association may be confounded by individuals' health status which is difficult to fully control for. Further studies are called for.
Notes
Cites: Am Heart J. 2011 May;161(5):950-521570528
Cites: J Psychiatr Res. 1975 Nov;12(3):189-981202204
Cites: Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):3-821621282
Cites: Age Ageing. 2012 Jan;41(1):118-2122086965
Cites: Arch Phys Med Rehabil. 2012 Sep;93(9):1609-1622484216
Cites: Age Ageing. 2003 Nov;32(6):619-2514600003
Cites: Aging Clin Exp Res. 2013 Dec;25(6):667-7524136449
Cites: J Psychiatr Res. 1982-1983;17(1):37-497183759
Cites: J Epidemiol Community Health. 1993 Aug;47(4):298-3028228766
Cites: BMJ. 1998 Sep 19;317(7161):802-89740574
Cites: Lancet. 2005 Nov 26;366(9500):1885-9316310556
Cites: Scand J Occup Ther. 2005 Mar;12(1):29-3916389996
Cites: J Epidemiol. 2006 Nov;16(6):261-7017085876
Cites: Gerontologist. 2007 Feb;47(1):78-8417327543
Cites: Gerontologist. 2007 Feb;47(1):96-10717327545
Cites: Arch Gerontol Geriatr. 2007 Nov-Dec;45(3):233-4217296237
Cites: Aust J Rural Health. 2008 Feb;16(1):5-1118186716
Cites: Prev Med. 2000 Jul;31(1):15-2210896840
Cites: Am J Epidemiol. 2002 Mar 15;155(6):507-1511882524
Cites: J Epidemiol Community Health. 2002 Dec;56(12):913-812461111
Cites: Aging Clin Exp Res. 2003 Apr;15(2):174-8312889850
Cites: Am J Epidemiol. 2008 Jan 15;167(2):240-817906296
Cites: Gerontologist. 2009 Jun;49(3):355-6719420315
Cites: J Aging Phys Act. 2006 Apr;14(2):203-1119462550
Cites: Clin Rehabil. 2009 Jun;23(6):558-6719403554
Cites: Soc Sci Med. 2009 Sep;69(5):754-6019604611
Cites: Soc Sci Med. 2009 Sep;69(6):964-7019643522
Cites: Int J Public Health. 2010 Feb;55(1):59-6919768384
Cites: J Am Geriatr Soc. 2010 Oct;58(10):1925-3020831722
Cites: J Am Geriatr Soc. 2010 Dec;58(12):2358-6221087220
Cites: J Urban Health. 2011 Feb;88(1):154-6721274644
Cites: Int J Sports Med. 2011 Mar;32(3):216-2221165808
Cites: J Aging Phys Act. 2011 Apr;19(2):117-3621558567
Cites: Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):55-6021420181
PubMed ID
23981906 View in PubMed
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Estimating occupational exposure to carcinogens in Quebec.

https://arctichealth.org/en/permalink/ahliterature112740
Source
Am J Ind Med. 2013 Sep;56(9):1040-50
Publication Type
Article
Date
Sep-2013
Author
France Labrèche
Patrice Duguay
Claude Ostiguy
Alexandre Boucher
Brigitte Roberge
Cheryl E Peters
Paul A Demers
Author Affiliation
Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST), Montréal, Québec, Canada. france.labreche@irsst.qc.ca
Source
Am J Ind Med. 2013 Sep;56(9):1040-50
Date
Sep-2013
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Age Factors
Aged
Carcinogens - analysis
Databases, Factual
Environmental monitoring
Female
Health Surveys
Humans
Industry
Male
Middle Aged
Occupational Exposure - analysis - statistics & numerical data
Occupational Health
Quebec
Sex Factors
Young Adult
Abstract
We estimated the extent of exposure to occupational carcinogens in Quebec, Canada, to help raise awareness of occupational cancers.
Proportions of workers exposed to 21 recognized and 17 probable carcinogens (according to Quebec occupational health regulation and the International Agency for Research on Cancer [IARC] classification) were extracted from various sources: workplace monitoring data, research projects, a population survey, radiation protection data, exposure estimates from the Carcinogen Exposure Canada (CAREX Canada) Project database, and published exposure data. These proportions were applied to Quebec labor force data.
Among the 38 studied, carcinogens with the largest proportions of exposed workers were solar radiation (6.6% of workers), night shift work/rotating shift work including nights (6.0%), diesel exhaust fumes (4.4%), wood dust (2.9%) and polycyclic aromatic hydrocarbons (2.0%). More than 15 carcinogens were identified in several industrial sectors, and up to 100,000 young workers are employed in these sectors.
Although crude, estimates obtained with different data sources allow identification of research and intervention priorities for cancer in Quebec.
PubMed ID
23804516 View in PubMed
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Exploration of biomarkers for total fish intake in pregnant Norwegian women.

https://arctichealth.org/en/permalink/ahliterature98999
Source
Public Health Nutr. 2010 Jan;13(1):54-62
Publication Type
Article
Date
Jan-2010
Author
Anne Lise Brantsaeter
Margaretha Haugen
Yngvar Thomassen
Dag G Ellingsen
Trond A Ydersbond
Tor-Arne Hagve
Jan Alexander
Helle Margrete Meltzer
Author Affiliation
Division of Environmental Medicine, Department of Food Safety and Nutrition, Norwegian Institute of Public Health, PO Box 4404 Nydalen, NO-04030 Oslo, Norway. anne.lise.brantsaeter@fhi.no
Source
Public Health Nutr. 2010 Jan;13(1):54-62
Date
Jan-2010
Language
English
Geographic Location
Norway
Publication Type
Article
Keywords
Adult
Arsenic - administration & dosage - blood
Biological Markers - blood - urine
Cohort Studies
Diet Records
Erythrocytes - chemistry
Fatty Acids, Omega-3 - administration & dosage - analysis
Female
Food Habits
Humans
Iodine - administration & dosage - urine
Mercury - administration & dosage - blood
Norway
Pregnancy
Questionnaires
Seafood - analysis
Selenium - administration & dosage - blood
Young Adult
Abstract
OBJECTIVE: Few biomarkers for dietary intake of various food groups have been established. The aim of the present study was to explore whether selenium (Se), iodine, mercury (Hg) or arsenic may serve as a biomarker for total fish and seafood intake in addition to the traditionally used n-3 fatty acids EPA and DHA. DESIGN: Intake of fish and seafood estimated by an FFQ was compared with intake assessed by a 4 d weighed food diary and with biomarkers in blood and urine. SETTING: Validation study in the Norwegian Mother and Child Cohort Study (MoBa). SUBJECTS: One hundred and nineteen women. RESULTS: Total fish/seafood intake (median 39 g/d) calculated with the MoBa FFQ was comparable to intake calculated by the food diary (median 30 g/d, rS = 0.37, P
Notes
RefSource: Public Health Nutr. 2009 Dec;12(12):2536-7
PubMed ID
19490733 View in PubMed
Less detail

Exposures to multiple pesticides and the risk of Hodgkin lymphoma in Canadian men.

https://arctichealth.org/en/permalink/ahliterature113182
Source
Cancer Causes Control. 2013 Sep;24(9):1661-73
Publication Type
Article
Date
Sep-2013
Author
Garthika Navaranjan
Karin Hohenadel
Aaron Blair
Paul A Demers
John J Spinelli
Punam Pahwa
John R McLaughlin
James A Dosman
Len Ritter
Shelley A Harris
Author Affiliation
Occupational Cancer Research Centre, 505 University Avenue, Toronto, ON, M5G 1X3, Canada.
Source
Cancer Causes Control. 2013 Sep;24(9):1661-73
Date
Sep-2013
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Age Factors
Canada
Case-Control Studies
Cholinesterase Inhibitors - poisoning
Environmental Exposure
Hodgkin Disease - chemically induced - pathology
Humans
Logistic Models
Male
Occupational Exposure
Pesticides - poisoning
Questionnaires
Risk factors
Young Adult
Abstract
To determine the risk of Hodgkin lymphoma (HL) associated with exposures to multiple pesticides grouped by various classes, including carcinogenic classifications.
Data collected in the Cross-Canada Study of Pesticides and Health, a population-based incident case-control study in six provinces conducted between 1991 and 1994, were analyzed using unconditional logistic regression. Cases (n = 316) were identified through provincial cancer registries and hospital records. Controls (n = 1,506) were frequency-matched to cases by age (± 2 years) within each province and were identified through provincial health records, telephone listings, or voter lists. The Cochran-Armitage test was used to check for trends within pesticide classes.
Overall, there was an increase in the risk of HL among all subjects who reported use of five or more insecticides (OR 1.88, 95% CI 0.92-3.87) and among subjects younger than 40 who reported use of two acetylcholinesterase inhibitors (OR 3.16, 95% CI 1.02-9.29). There was an elevated odds ratio associated with reported use of three or more probably carcinogenic pesticides (OR 2.47, 95% CI 1.06-5.75), but no increase in risk for use of possibly carcinogenic pesticides. The risk of HL from reported use of fungicides or any pesticides was greater for cases diagnosed before age 40 than for cases diagnosed at or after age 40. When analyses excluded proxy respondents, OR estimates strengthened in some circumstances.
This study found associations between HL and fungicides, insecticides, specifically acetylcholinesterase inhibitors, and pesticides previously identified as probable human carcinogens. These associations should be further evaluated, specifically in relation to age at diagnosis.
Notes
Cites: Mol Pathol. 2000 Oct;53(5):262-911091850
Cites: Cancer Causes Control. 2001 Aug;12(6):509-1711519759
Cites: Cancer Epidemiol Biomarkers Prev. 2001 Nov;10(11):1155-6311700263
Cites: Occup Environ Med. 2003 Sep;60(9):E1112937207
Cites: Br J Cancer. 1981 Feb;43(2):169-767470379
Cites: JAMA. 1986 Sep 5;256(9):1141-73801091
Cites: Scand J Work Environ Health. 1988 Aug;14(4):224-303175554
Cites: Am J Ind Med. 1990;18(3):285-932220833
Cites: Recent Results Cancer Res. 1990;120:132-452236872
Cites: Lancet. 1991 Feb 9;337(8737):320-21671232
Cites: Epidemiology. 1990 Sep;1(5):349-562078610
Cites: Am J Epidemiol. 1991 Aug 15;134(4):348-551877595
Cites: J Pathol. 1992 Jan;166(1):1-51311374
Cites: Epidemiology. 1993 Jan;4(1):55-628420582
Cites: Cancer Causes Control. 1996 May;7(3):312-218734824
Cites: Ann Oncol. 1996;7 Suppl 4:5-108836402
Cites: Int J Cancer. 1997 Feb 7;70(4):375-829033642
Cites: Occup Med. 1997 Apr-Jun;12(2):269-899220486
Cites: J Clin Oncol. 2005 Aug 1;23(22):5052-6015955904
Cites: J Occup Environ Med. 2006 Mar;48(3):264-7416531830
Cites: Cancer Causes Control. 2007 Dec;18(10):1209-2617874193
Cites: Occup Environ Med. 2009 May;66(5):291-819017688
Cites: BMC Cancer. 2009;9:14119432977
Cites: Int J Cancer. 2010 Dec 15;127(12):2893-91721351269
Cites: Int J Environ Res Public Health. 2011 Jun;8(6):2320-3021776232
Cites: J Agromedicine. 2012 Jan;17(1):30-922191501
PubMed ID
23756639 View in PubMed
Less detail

Exposure to pesticides and metal contaminants of fertilizer among tree planters.

https://arctichealth.org/en/permalink/ahliterature133737
Source
Ann Occup Hyg. 2011 Aug;55(7):752-63
Publication Type
Article
Date
Aug-2011
Author
Melanie Gorman Ng
Ernst Stjernberg
Mieke Koehoorn
Paul A Demers
Hugh W Davies
Author Affiliation
School of Environmental Health, University of British Columbia, Canada. melanie.gormanng@iom-world.org
Source
Ann Occup Hyg. 2011 Aug;55(7):752-63
Date
Aug-2011
Language
English
Publication Type
Article
Keywords
Adult
British Columbia
Canada
Chromatography, Liquid
Eating
Fertilizers - analysis - toxicity
Forestry - methods
Fungicides, Industrial - analysis - toxicity
Hand Disinfection - standards
Humans
Hygiene
Inhalation Exposure - analysis
Metals - analysis - toxicity
Occupational Exposure - analysis
Pesticide Residues - analysis - toxicity
Pesticides - analysis - toxicity
Plasma
Protective Clothing - standards
Soil Pollutants - analysis - toxicity
Spectrophotometry
Trees - chemistry
Abstract
In British Columbia, Canada, harvested forests are manually replanted by seasonal workers. The work is known to be physically demanding and ergonomically difficult, and recently, there have been concerns over chemical exposures due to pesticide residues on seedlings, fertilizers (often applied alongside seedlings), and potential metal contamination of these fertilizers. This study aimed to characterize metal and pesticide exposure among a sample of British Columbia tree planters. Between May 2006 and April 2007, exposure measurements were taken from 54 tree planters at five geographically disperse worksites throughout British Columbia. Four worksites were using fertilizer and one was not. Metal concentrations were measured by inductively coupled plasma mass spectrometry on post-shift hand wipes, full-shift personal air sample, bulk soil, seedling root balls, and fertilizer samples. Pesticides were measured on post-shift hand wipes and on bulk seedling samples. Seedling nursery pesticide application records were used to focus pesticide analyses on pesticides known to have been applied to the seedlings used at the study sites. Carbamate pesticides were analyzed by high-performance liquid chromatography/mass spectroscopy and all other pesticides by gas chromatography mass spectrometry. No evidence was found that tree planters who worked with fertilizer were at an elevated risk of exposure to arsenic, lead, cadmium, chromium, and nickel relative to tree planters who did not. Pesticide residues were found on seedlings taken from work sites early in the tree planting season in April 2007. At these worksites, the fungicides chlorothalonil and iprodione were found on the skin of workers at low levels (range 0.37-106.3 ng cm(-2) and 0.48-15.9 ng cm(-2), respectively), providing evidence for exposure potential. Very poor hygiene conditions were observed at all tree planting work sites. Hand washing facilities were not available at work sites and only 5.6% of subjects reported hand washing during the work day, including prior to eating or smoking. Gloves were worn by all subjects but no personal protective equipment programs existed to train workers in the correct use or selection of gloves, and consequentially, many glove choices were inappropriate. The lack of hand washing facilities combined with incorrect glove use could increase the duration of dermal exposure and increase the risk of hand-to-mouth ingestion exposure.
PubMed ID
21673126 View in PubMed
Less detail

Fear of moving outdoors and development of outdoor walking difficulty in older people.

https://arctichealth.org/en/permalink/ahliterature151341
Source
J Am Geriatr Soc. 2009 Apr;57(4):634-40
Publication Type
Article
Date
Apr-2009
Author
Merja Rantakokko
Minna Mänty
Susanne Iwarsson
Timo Törmäkangas
Raija Leinonen
Eino Heikkinen
Taina Rantanen
Author Affiliation
Department of Health Sciences, Finnish Centre for Interdisciplinary Gerontology, University of Jyväskylä, Jyväskylä, Finland. merja.rantakokko@sport.jyu.fi
Source
J Am Geriatr Soc. 2009 Apr;57(4):634-40
Date
Apr-2009
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Chi-Square Distribution
Cross-Sectional Studies
Environment
Fear
Female
Finland
Geriatric Assessment
Humans
Interviews as Topic
Logistic Models
Male
Mobility Limitation
Musculoskeletal Diseases - complications
Prospective Studies
Residence Characteristics
Risk factors
Socioeconomic Factors
Abstract
To study which individual characteristics and environmental factors correlate with fear of moving outdoors and whether fear of moving outdoors predicts development of mobility limitation.
Observational prospective cohort study and cross-sectional analyses.
Community and research center.
Seven hundred twenty-seven community-living people aged 75 to 81 were interviewed at baseline, of whom 314 took part in a 3.5-year follow-up.
Fear of moving outdoors and its potential individual and environmental correlates were assessed at baseline. Perceived difficulties in walking 0.5 km and 2 km were assessed twice a year over a 3.5-year period.
At baseline, 65% of the women and 29% of the men reported fear of moving outdoors. Poor socioeconomic status; musculoskeletal diseases; slow walking speed; and the presence of poor street conditions, hills in the nearby environment, and noisy traffic correlated with fear of moving outdoors. At the first 6-month follow-up, participants with fear of moving outdoors had more than four times the adjusted risk (odds ratio (OR)=4.6, 95% confidence interval (CI)=1.92-11.00) of developing difficulties in walking 0.5 km and a three times greater adjusted risk (OR=3.10, 95% CI=1.49-6.46) for developing difficulty in walking 2 km compared with those without fear. The difference in the prevalence of walking difficulties remained statistically significant over the 3.5-year follow-up (P=.02 and P=.009, respectively).
Fear of moving outdoors is common in older adults and increases the risk of developing self-reported difficulties in walking 0.5 km and 2 km. Knowledge about individual and environmental factors underlying fear of moving outdoors and finding ways to alleviate fear of moving outdoors are important for community planning and prevention of disability.
PubMed ID
19392955 View in PubMed
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Fertilizer use and self-reported respiratory and dermal symptoms among tree planters.

https://arctichealth.org/en/permalink/ahliterature118552
Source
J Occup Environ Hyg. 2013;10(1):36-45
Publication Type
Article
Date
2013
Author
Melanie Gorman Ng
Ernst Stjernberg
Mieke Koehoorn
Paul A Demers
Meghan Winters
Hugh W Davies
Author Affiliation
Institute of Occupational Medicine, Edinburgh, UK. Melanie.GormanNg@iom-world.org
Source
J Occup Environ Hyg. 2013;10(1):36-45
Date
2013
Language
English
Publication Type
Article
Keywords
Adult
Alberta - epidemiology
British Columbia - epidemiology
Causality
Comorbidity
Female
Fertilizers - adverse effects
Forestry
Humans
Incidence
Lung Diseases - chemically induced - epidemiology
Male
Middle Aged
Occupational Diseases - chemically induced - epidemiology
Occupational Exposure - adverse effects - analysis - statistics & numerical data
Odds Ratio
Questionnaires
Skin Diseases - chemically induced - epidemiology
Smoking - epidemiology
Soil Pollutants - adverse effects - analysis
Trees
Young Adult
Abstract
In British Columbia, some tree planting operations require workers to fertilize planted seedlings with polymer-coated nitrogen, phosphorus, and potassium (NPK) fertilizers. This study examined respiratory and dermal health associated with fertilizer exposure among tree planters. We interviewed 223 tree planters using an adapted version of the American Thoracic Society questionnaire supplemented with questions on dermal health. Subjects were grouped by categories of increasing duration of exposure, with workers who had not worked with fertilizer as a reference group. The relationship between exposure and reported work-related symptoms was analyzed using logistic regression, adjusting for age, cumulative tobacco cigarettes smoked, marijuana smoking status, sex, and exposure to abrasive spruce needles. An elevated odds ratio was seen for work-related cough, phlegm, nasal symptoms, nosebleed, and skin rash in the highest exposure group (>37 days of fertilizer use in the past 2 years) but was significant only for phlegm (odds ratio = 3.59, 95% confidence interval = 1.10-11.70). Trends of increasing odds ratios with increasing exposure were seen for cough, phlegm, nasal symptoms, and skin rash. The results suggest a weak association between respiratory and dermal irritation and work with fertilizer. Results highlight the need for further exposure monitoring within the tree planting industry, and larger studies to investigate the relationship between work with fertilizer and respiratory and dermal health symptoms. [Supplementary materials are available for this article. Go to the publisher's online edition of the Journal of Occupational and Environmental Hygiene for the following free supplemental resource: a PDF file containing a respiratory and dermal health questionnaire.].
PubMed ID
23194098 View in PubMed
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Fish liver and seagull eggs, vitamin D-rich foods with a shadow: results from the Norwegian Fish and Game Study.

https://arctichealth.org/en/permalink/ahliterature127159
Source
Mol Nutr Food Res. 2012 Mar;56(3):388-98
Publication Type
Article
Date
Mar-2012
Author
Bryndis E Birgisdottir
Anne L Brantsaeter
Helen E Kvalem
Helle K Knutsen
Margaretha Haugen
Jan Alexander
Ragna B Hetland
Lage Aksnes
Helle M Meltzer
Author Affiliation
Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway. bryndis.eva.birgisdottir@fhi.no
Source
Mol Nutr Food Res. 2012 Mar;56(3):388-98
Date
Mar-2012
Language
English
Publication Type
Article
Keywords
Adult
Aged
Animals
Charadriiformes
Databases, Factual
Diet
Dioxins - analysis - metabolism - toxicity
Eggs
Female
Fish Oils - administration & dosage
Fishes
Food contamination - analysis
Humans
Liver - chemistry
Male
Middle Aged
Norway
Polychlorinated Biphenyls - analysis - metabolism - toxicity
Questionnaires
Vitamin D - administration & dosage - analysis
Vitamins - administration & dosage - analysis
Abstract
Fish liver, fish liver oil, oily fish and seagull eggs have been major sources of vitamin D for the coastal population of Norway. They also provide dioxin and polychlorinated dioxin-like compounds (dl-compounds), which may interfere with vitamin D homeostasis. We investigated whether serum 25-hydroxyvitamin D (25(OH)D) might be compromised by concomitant intake of dl-compounds.
We studied 182 adults participating in the Norwegian Fish and Game Study. Participants who consumed fish liver and/or seagull eggs had higher dl-compound intake and blood concentrations than non-consumers (p
PubMed ID
22319024 View in PubMed
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