Skip header and navigation

Refine By

41 records – page 1 of 3.

Active aging - resilience and external support as modifiers of the disablement outcome: AGNES cohort study protocol.

https://arctichealth.org/en/permalink/ahliterature299192
Source
BMC Public Health. 2018 05 02; 18(1):565
Publication Type
Journal Article
Date
05-02-2018
Author
Taina Rantanen
Milla Saajanaho
Laura Karavirta
Sini Siltanen
Merja Rantakokko
Anne Viljanen
Timo Rantalainen
Katja Pynnönen
Anu Karvonen
Inna Lisko
Lotta Palmberg
Johanna Eronen
Eeva-Maija Palonen
Timo Hinrichs
Markku Kauppinen
Katja Kokko
Erja Portegijs
Author Affiliation
Gerontology Research Center, Faculty of Sport and Health Sciences, Univerisity of Jyvaskyla, P.O. Box 35 (viv 149), 40014, Jyväskylä, Finland. taina.rantanen@jyu.fi.
Source
BMC Public Health. 2018 05 02; 18(1):565
Date
05-02-2018
Language
English
Publication Type
Journal Article
Keywords
Aged
Aged, 80 and over
Aging - psychology
Cohort Studies
Disabled persons - statistics & numerical data
Exercise
Female
Finland
Health Behavior
Health Literacy
Humans
Male
Resilience, Psychological
Social Support
Abstract
Population aging increases the need for knowledge on positive aspects of aging, and contributions of older people to their own wellbeing and that of others. We defined active aging as an individual's striving for elements of wellbeing with activities as per their goals, abilities and opportunities. This study examines associations of health, health behaviors, health literacy and functional abilities, environmental and social support with active aging and wellbeing. We will develop and validate assessment methods for physical activity and physical resilience suitable for research on older people, and examine their associations with active aging and wellbeing. We will examine cohort effects on functional phenotypes underlying active aging and disability.
For this population-based study, we plan to recruit 1000 participants aged 75, 80 or 85 years living in central Finland, by drawing personal details from the population register. Participants are interviewed on active aging, wellbeing, disability, environmental and social support, mobility, health behavior and health literacy. Physical activity and heart rate are monitored for 7 days with wearable sensors. Functional tests include hearing, vision, muscle strength, reaction time, exercise tolerance, mobility, and cognitive performance. Clinical examination by a nurse and physician includes an electrocardiogram, tests of blood pressure, orthostatic regulation, arterial stiffness, and lung function, as well as a review of chronic and acute conditions and prescribed medications. C-reactive protein, small blood count, cholesterol and vitamin D are analyzed from blood samples. Associations of factors potentially underlying active aging and wellbeing will be studied using multivariate methods. Cohort effects will be studied by comparing test results of physical and cognitive functioning with results of a cohort examined in 1989-90.
The current study will renew research on positive gerontology through the novel approach to active aging and by suggesting new biomarkers of resilience and active aging. Therefore, high interdisciplinary impact is expected. This cross-sectional study will not provide knowledge on temporal order of events or causality, but an innovative cross-sectional dataset provides opportunities for emergence of novel creative hypotheses and theories.
PubMed ID
29716566 View in PubMed
Less detail

Barriers to outdoor physical activity and unmet physical activity need in older adults.

https://arctichealth.org/en/permalink/ahliterature266937
Source
Prev Med. 2014 Oct;67:106-11
Publication Type
Article
Date
Oct-2014
Author
Johanna Eronen
Mikaela B von Bonsdorff
Timo Törmäkangas
Merja Rantakokko
Erja Portegijs
Anne Viljanen
Taina Rantanen
Source
Prev Med. 2014 Oct;67:106-11
Date
Oct-2014
Language
English
Publication Type
Article
Keywords
Aged
Aged, 80 and over
Aging
Cohort Studies
Cross-Sectional Studies
Environment
Environment Design
Exercise
Female
Finland
Geriatric Assessment
Health status
Humans
Male
Mobility Limitation
Questionnaires
Walking
Abstract
To profile participants based on reported outdoor physical activity barriers using a data-driven approach, describe the profiles and study their association with unmet physical activity need.
Cross-sectional analyses of 848 community-dwelling men and women aged 75-90 living in Central Finland in 2012. Barriers to outdoor physical activity and unmet physical activity need were enquired with a questionnaire. The latent profiles were identified by profiling participants into latent groups using a mixture modeling technique on the multivariate set of indicators of outdoor physical activity barriers. A path model was used to study the associations of the profiles with unmet physical activity need.
Five barrier profiles were identified. Profile A was characterized with minor barriers, profile B with weather barriers, profile C with health and weather barriers, profile D with barriers concerning insecurity, health and weather; and profile E with mobility and health barriers. The participants in the profiles differed in the proportion of individual and environmental barriers. The risk for unmet physical activity need was highest among people whose severe mobility difficulties restricted their outdoor physical activity.
Outdoor physical activity barriers reflect the imbalance in person-environment fit among older people, manifested as unmet physical activity need.
PubMed ID
25045839 View in PubMed
Less detail

Body fat and mobility are explained by common genetic and environmental influences in older women.

https://arctichealth.org/en/permalink/ahliterature157662
Source
Obesity (Silver Spring). 2008 Jul;16(7):1616-21
Publication Type
Article
Date
Jul-2008
Author
Alfredo Ortega-Alonso
Sarianna Sipilä
Urho M Kujala
Jaakko Kaprio
Taina Rantanen
Author Affiliation
Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland. alfredo.ortega@sport.jyu.fi
Source
Obesity (Silver Spring). 2008 Jul;16(7):1616-21
Date
Jul-2008
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Adiposity - genetics
Age Factors
Aged
Aging - genetics
Electric Impedance
Environment
Female
Finland
Genetic Predisposition to Disease
Humans
Locomotion - genetics
Middle Aged
Mobility Limitation
Models, Genetic
Obesity - genetics - physiopathology
Physical Endurance - genetics
Risk factors
Twins, Dizygotic - genetics
Twins, Monozygotic - genetics
Walking
Abstract
In older adults, mobility limitations often coexist with overweight or obesity, suggesting that similar factors may underlie both traits. This study examined the extent to which genetic and environmental influences explain the association between adiposity and mobility in older women. Body fat percentage (bioimpedance test), walking speed over 10 m, and distance walked in a 6-min test were evaluated in 92 monozygotic (MZ) and 104 dizygotic (DZ) pairs of twin sisters reared together, aged 63-76 years. Genetic and environmental influences on each trait were estimated using age-adjusted multivariate genetic modeling. The analyses showed that the means (and s.d.) for body fat percentage, walking speed, and walking endurance were 33.2+/-7.3%, 1.7+/-0.3 m/s and 529.7+/-75.4 m, respectively. The phenotypic correlation between adiposity and walking speed was -0.32 and between adiposity and endurance it was -0.33. Genetic influences explained 80% of the association between adiposity and speed, and 65% of adiposity and walking endurance. Cross-trait genetic influences accounted for 12% of the variability in adiposity, 56% in walking speed, and 34% in endurance. Trait-specific genetic influences were also detected for adiposity (54%) and walking endurance (13%), but not speed. In conclusion, among community-living older women, an inverse association was found between adiposity and mobility that was mostly due to the effect of shared genes. This result suggests that the identification of genetic variants for body fat metabolism may also provide understanding of the development of mobility limitations in older women.
PubMed ID
18421266 View in PubMed
Less detail

Determinants of plasma PCB, brominated flame retardants, and organochlorine pesticides in pregnant women and 3 year old children in The Norwegian Mother and Child Cohort Study.

https://arctichealth.org/en/permalink/ahliterature273849
Source
Environ Res. 2016 Apr;146:136-44
Publication Type
Article
Date
Apr-2016
Author
Ida Henriette Caspersen
Helen Engelstad Kvalem
Margaretha Haugen
Anne Lise Brantsæter
Helle Margrete Meltzer
Jan Alexander
Cathrine Thomsen
May Frøshaug
Nanna Margrethe Bruun Bremnes
Sharon Lynn Broadwell
Berit Granum
Manolis Kogevinas
Helle Katrine Knutsen
Source
Environ Res. 2016 Apr;146:136-44
Date
Apr-2016
Language
English
Publication Type
Article
Keywords
Child, Preschool
Cohort Studies
Demography
Diet
Environmental Exposure
Environmental monitoring
Environmental pollutants - blood
Female
Flame Retardants - metabolism
Humans
Hydrocarbons, Brominated - blood
Hydrocarbons, Chlorinated - blood
Life Style
Norway
Pesticides - blood
Polybrominated Biphenyls - blood
Polychlorinated biphenyls - blood
Pregnancy
Abstract
Exposure to persistent organic pollutants (POPs) during prenatal and postnatal life has been extensively studied in relation to adverse health effects in children.
The aim was to identify determinants of the concentrations of polychlorinated biphenyls (PCBs), brominated flame retardants (polybrominated diphenyl ethers, PBDEs; polybrominated biphenyl, PBB), and organochlorine pesticides (OCPs) in blood samples from pregnant women and children in The Norwegian Mother and Child Cohort Study (MoBa).
Blood samples were collected from two independent subsamples within MoBa; a group of women (n=96) enrolled in mid-pregnancy during the years 2002-2008 and a group of 3 year old children (n=99) participating during 2010-2011. PCB congeners (74, 99, 138, 153, 180, 170, 194, 209, 105, 114, 118, 156, 157, 167, and 189), brominated flame retardants (PBDE-28, 47, 99, 100, 153, 154, and PBB-153), as well as the OCPs hexachlorobenzene (HCB), oxychlordane, 4,4'dichlorodiphenyltrichloroethane (DDT), and 4,4'dichlorodiphenyldichloroethylene (DDE) were measured in both pregnant women and children.
Age, low parity, and low pre-pregnant BMI were the most important determinants of increased plasma concentrations of POPs in pregnant women. In 3 year old children, prolonged breastfeeding duration was a major determinant of increased POP concentrations. Estimated dietary exposure to PCBs during pregnancy was positively associated with plasma concentrations in 3 year old children, but not in pregnant women. Plasma concentrations were approximately 40% higher in children compared to pregnant women.
Several factors associated with exposure and toxicokinetics, i.e. accumulation, excretion and transfer via breastmilk of POPs were the main predictors of POP levels in pregnant women and children. Diet, which is the main exposure source for these compounds in the general population, was found to predict PCB levels only among children. For the PBDEs, for which non-dietary sources are more important, toxicokinetic factors appeared to have less predictive impact.
PubMed ID
26749444 View in PubMed
Less detail

Dietary acrylamide intake during pregnancy and fetal growth-results from the Norwegian mother and child cohort study (MoBa).

https://arctichealth.org/en/permalink/ahliterature118477
Source
Environ Health Perspect. 2013 Mar;121(3):374-9
Publication Type
Article
Date
Mar-2013
Author
Talita Duarte-Salles
Hans von Stedingk
Berit Granum
Kristine B Gützkow
Per Rydberg
Margareta Törnqvist
Michelle A Mendez
Gunnar Brunborg
Anne Lise Brantsæter
Helle Margrete Meltzer
Jan Alexander
Margaretha Haugen
Author Affiliation
Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway.
Source
Environ Health Perspect. 2013 Mar;121(3):374-9
Date
Mar-2013
Language
English
Publication Type
Article
Keywords
Acrylamide - administration & dosage - pharmacology
Cohort Studies
Diet
Environmental Exposure
Female
Fetal Development - drug effects
Hemoglobins - chemistry
Humans
Norway
Pregnancy
Questionnaires
Abstract
Acrylamide has shown developmental and reproductive toxicity in animals, as well as neurotoxic effects in humans with occupational exposures. Because it is widespread in food and can pass through the human placenta, concerns have been raised about potential developmental effects of dietary exposures in humans.
We assessed associations of prenatal exposure to dietary acrylamide with small for gestational age (SGA) and birth weight.
This study included 50,651 women in the Norwegian Mother and Child Cohort Study (MoBa). Acrylamide exposure assessment was based on intake estimates obtained from a food frequency questionnaire (FFQ), which were compared with hemoglobin (Hb) adduct measurements reflecting acrylamide exposure in a subset of samples (n = 79). Data on infant birth weight and gestational age were obtained from the Medical Birth Registry of Norway. Multivariable regression was used to estimate associations between prenatal acrylamide and birth outcomes.
Acrylamide intake during pregnancy was negatively associated with fetal growth. When women in the highest quartile of acrylamide intake were compared with women in the lowest quartile, the multivariable-adjusted odds ratio (OR) for SGA was 1.11 (95% CI: 1.02, 1.21) and the coefficient for birth weight was -25.7 g (95% CI: -35.9, -15.4). Results were similar after excluding mothers who smoked during pregnancy. Maternal acrylamide- and glycidamide-Hb adduct levels were correlated with estimated dietary acrylamide intakes (Spearman correlations = 0.24; 95% CI: 0.02, 0.44; and 0.48; 95% CI: 0.29, 0.63, respectively).
Lowering dietary acrylamide intake during pregnancy may improve fetal growth.
Notes
Cites: Scand J Work Environ Health. 2001 Aug;27(4):219-2611560335
Cites: Paediatr Perinat Epidemiol. 2009 Nov;23(6):597-60819840297
Cites: Trends Endocrinol Metab. 2002 Nov;13(9):364-812367816
Cites: Chemotherapy. 2002;48(6):267-7412673101
Cites: Toxicol Sci. 2003 Sep;75(1):7-1512805639
Cites: Int Arch Occup Environ Health. 2004 Apr;77(3):213-614740221
Cites: IARC Monogr Eval Carcinog Risks Hum. 1994;60:389-4337869577
Cites: Chem Res Toxicol. 1997 Jan;10(1):78-849074806
Cites: Mutat Res. 2005 Feb 7;580(1-2):3-2015668103
Cites: Food Chem Toxicol. 2005 Mar;43(3):365-41015680675
Cites: Birth Defects Res B Dev Reprod Toxicol. 2005 Feb;74(1):17-11315729727
Cites: Crit Rev Toxicol. 2006 Jul-Aug;36(6-7):481-60816973444
Cites: Int J Epidemiol. 2006 Oct;35(5):1146-5016926217
Cites: Toxicol Sci. 2007 Jul;98(1):110-717449897
Cites: Matern Child Nutr. 2008 Jan;4(1):14-2718171404
Cites: J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Oct 1;878(27):2483-9020399714
Cites: Food Chem Toxicol. 2011 Aug;49(8):1843-821571030
Cites: Int J Epidemiol. 2011 Jun;40(3):647-6121324938
Cites: Chem Res Toxicol. 2011 Nov 21;24(11):1957-6521882862
Cites: Int J Hyg Environ Health. 2012 Feb;215(2):216-921937271
Cites: Food Chem Toxicol. 2012 Jul;50(7):2531-922525869
Cites: Environ Health Perspect. 2012 Dec;120(12):1739-4523092936
Cites: Food Chem Toxicol. 2010 Nov;48(11):3098-10820696196
Cites: Nutrition. 2011 Mar;27(3):343-5021329872
Cites: Am J Clin Nutr. 2000 May;71(5 Suppl):1344S-52S10799412
Cites: Acta Obstet Gynecol Scand. 2000 Jun;79(6):435-910857866
Cites: Acta Obstet Gynecol Scand. 2000 Jun;79(6):440-910857867
Cites: Chem Res Toxicol. 2000 Jun;13(6):517-2210858325
Cites: Semin Neonatol. 2000 Aug;5(3):231-4110956448
Cites: Matern Child Nutr. 2008 Jan;4(1):28-4318171405
Cites: Eur J Clin Nutr. 2008 Mar;62(3):314-2317356560
Cites: Cancer Causes Control. 2008 Apr;19(3):273-8117985202
Cites: Mutat Res. 2008 May 31;653(1-2):50-618485803
Cites: Food Chem Toxicol. 2008 Aug;46(8):2808-1418599176
Cites: Toxicol Lett. 2008 Nov 10;182(1-3):50-618790027
Cites: Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):5-1019124475
Cites: Toxicol Sci. 2009 Mar;108(1):90-919131562
Cites: Am J Clin Nutr. 2009 Mar;89(3):773-719158207
Cites: Cancer Causes Control. 2009 Apr;20(3):269-7818855107
Cites: Int J Cancer. 2009 May 15;124(10):2384-9019142870
Cites: J Agric Food Chem. 2002 Aug 14;50(17):4998-500612166997
PubMed ID
23204292 View in PubMed
Less detail

Dietary benzo(a)pyrene intake during pregnancy and birth weight: associations modified by vitamin C intakes in the Norwegian Mother and Child Cohort Study (MoBa).

https://arctichealth.org/en/permalink/ahliterature107027
Source
Environ Int. 2013 Oct;60:217-23
Publication Type
Article
Date
Oct-2013
Author
Talita Duarte-Salles
Michelle A Mendez
Helle Margrete Meltzer
Jan Alexander
Margaretha Haugen
Author Affiliation
Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway. Electronic address: duartesallest@fellows.iarc.fr.
Source
Environ Int. 2013 Oct;60:217-23
Date
Oct-2013
Language
English
Publication Type
Article
Keywords
Adult
Ascorbic Acid - pharmacology
Benzo(a)pyrene - administration & dosage - analysis - toxicity
Birth Weight - drug effects
Child
Cohort Studies
Diet - statistics & numerical data
Female
Fetal Development - drug effects
Food - classification
Food Contamination - analysis - statistics & numerical data
Heredodegenerative Disorders, Nervous System - chemically induced
Humans
Infant
Maternal Exposure - statistics & numerical data
Microphthalmos - chemically induced
Multivariate Analysis
Mutagenicity Tests
Norway - epidemiology
Parity
Polycyclic Hydrocarbons, Aromatic - toxicity
Pregnancy
Pregnancy Outcome - epidemiology
Prenatal Exposure Delayed Effects - epidemiology
Abstract
Maternal exposure to polycyclic aromatic hydrocarbons (PAH) during pregnancy has been associated with reduced fetal growth. However, the role of diet, the main source of PAH exposure among non-smokers, remains uncertain.
To assess associations between maternal exposure to dietary intake of the genotoxic PAH benzo(a)pyrene [B(a)P] during pregnancy and birth weight, exploring potential effect modification by dietary intakes of vitamins C, E and A, hypothesized to influence PAH metabolism.
This study included 50,651 women in the Norwegian Mother and Child Cohort Study (MoBa). Dietary B(a)P and nutrient intakes were estimated based on total consumption obtained from a food frequency questionnaire (FFQ) and estimated based on food composition data. Data on infant birth weight were obtained from the Medical Birth Registry of Norway (MBRN). Multivariate regression was used to assess associations between dietary B(a)P and birth weight, evaluating potential interactions with candidate nutrients.
The multivariate-adjusted coefficient (95%CI) for birth weight associated with maternal energy-adjusted B(a)P intake was -20.5g (-31.1, -10.0) in women in the third compared with the first tertile of B(a)P intake. Results were similar after excluding smokers. Significant interactions were found between elevated intakes of vitamin C (>85mg/day) and dietary B(a)P during pregnancy for birth weight (P
PubMed ID
24071023 View in PubMed
Less detail

Dietary exposure to dioxins and PCBs in a large cohort of pregnant women: results from the Norwegian Mother and Child Cohort Study (MoBa).

https://arctichealth.org/en/permalink/ahliterature108262
Source
Environ Int. 2013 Sep;59:398-407
Publication Type
Article
Date
Sep-2013
Author
Ida H Caspersen
Helle K Knutsen
Anne Lise Brantsæter
Margaretha Haugen
Jan Alexander
Helle Margrete Meltzer
Helen E Kvalem
Author Affiliation
Norwegian Institute of Public Health, Oslo, Norway. ida.henriette.caspersen@fhi.no
Source
Environ Int. 2013 Sep;59:398-407
Date
Sep-2013
Language
English
Publication Type
Article
Keywords
Adult
Body Burden
Cohort Studies
Diet - adverse effects
Dioxins - administration & dosage - blood
Environmental Exposure
Environmental Pollutants - administration & dosage - analysis - blood
Female
Fish Products - adverse effects - analysis
Food Contamination
Humans
Norway
Polychlorinated Biphenyls - administration & dosage - blood
Tetrachlorodibenzodioxin - blood
Young Adult
Abstract
Exposure to dioxins and polychlorinated biphenyls (PCBs) during pregnancy and breastfeeding may result in adverse health effects in children. Prenatal exposure is determined by the concentrations of dioxins and PCBs in maternal blood, which reflect the body burden obtained by long term dietary exposure. The aims of this study were (1) to describe dietary exposure and important dietary sources to dioxins and PCBs in a large group of pregnant women and (2) to identify maternal characteristics associated with high dietary exposure to dioxins and PCBs. Dietary exposure to dioxins (sum of toxic equivalents (TEQs) from dioxin-like (dl) compounds) and PCB-153 in 83,524 pregnant women (gestational weeks 17-22) who participated in the Norwegian Mother and Child Cohort Study (MoBa) during the years 2002-2009 was calculated based on a food frequency questionnaire (FFQ) and a database of dioxin and PCB concentrations in Norwegian food. The median (interquartile range, IQR) intake of PCB-153 (marker of ndl-PCBs) was 0.81 (0.77) ng/kg bw/day. For dioxins and dioxin-like PCBs, the median (IQR) intake was 0.56 (0.37) pg TEQ/kg bw/day. Moreover, 2.3% of the participants had intakes exceeding the tolerable weekly intake (TWI) of 14pg TEQ/kg bw/week. Multiple regression analysis showed that dietary exposure was positively associated with maternal age, maternal education, weight gain during pregnancy, being a student, and alcohol consumption during pregnancy and negatively associated with pre-pregnancy BMI and smoking. A high dietary exposure to PCB-153 or dl-compounds (TEQ) was mainly explained by the consumption of seagull eggs and/or pate with fish liver and roe. Women who according to Norwegian recommendations avoid these food items generally do not have dietary exposure above the tolerable intake of dioxins and dl-PCBs.
PubMed ID
23911340 View in PubMed
Less detail

Do Associations Between Perceived Environmental and Individual Characteristics and Walking Limitations Depend on Lower Extremity Performance Level?

https://arctichealth.org/en/permalink/ahliterature291084
Source
J Aging Health. 2017 Jun; 29(4):640-656
Publication Type
Comparative Study
Journal Article
Date
Jun-2017
Author
Ritva Sakari
Merja Rantakokko
Erja Portegijs
Susanne Iwarsson
Sarianna Sipilä
Anne Viljanen
Taina Rantanen
Author Affiliation
1 University of Jyvaskyla, Finland.
Source
J Aging Health. 2017 Jun; 29(4):640-656
Date
Jun-2017
Language
English
Publication Type
Comparative Study
Journal Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Cross-Sectional Studies
Disability Evaluation
Environment
Female
Geriatric Assessment - methods
Humans
Independent living
Interviews as Topic
Lower Extremity - physiopathology
Male
Mobility Limitation
Perception
Physical Fitness - physiology
Sweden
Task Performance and Analysis
Walking - physiology
Abstract
The aim of this study was to analyze whether the associations between perceived environmental and individual characteristics and perceived walking limitations in older people differ between those with intact and those with poorer lower extremity performance.
Persons aged 75 to 90 ( N = 834) participated in interviews and performance tests in their homes. Standard questionnaires were used to obtain walking difficulties; environmental barriers to and, facilitators of, mobility; and perceived individual hindrances to outdoor mobility. Lower extremity performance was tested using Short Physical Performance Battery (SPPB).
Among those with poorer lower extremity performance, the likelihood for advanced walking limitations was, in particular, related to perceived poor safety in the environment, and among those with intact performance to perceived social issues, such as lack of company, as well as to long distances.
The environmental correlates of walking limitations seem to depend on the level of lower extremity performance.
PubMed ID
27056910 View in PubMed
Less detail

Effect of dietary factors in pregnancy on risk of pregnancy complications: results from the Norwegian Mother and Child Cohort Study.

https://arctichealth.org/en/permalink/ahliterature134772
Source
Am J Clin Nutr. 2011 Dec;94(6 Suppl):1970S-1974S
Publication Type
Article
Date
Dec-2011
Author
Helle Margrete Meltzer
Anne Lise Brantsæter
Roy M Nilsen
Per Magnus
Jan Alexander
Margareta Haugen
Author Affiliation
Divisions of Environmental Medicine and Epidemiology, Norwegian Institute of Public Health, Oslo, Norway. helle.margrete.meltzer@fhi.no
Source
Am J Clin Nutr. 2011 Dec;94(6 Suppl):1970S-1974S
Date
Dec-2011
Language
English
Publication Type
Article
Keywords
Birth weight
Diet, Mediterranean
European Continental Ancestry Group
Female
Folic Acid - administration & dosage
Food Habits
Humans
Norway - epidemiology
Nutrition Assessment
Nutritional Status
Pre-Eclampsia - epidemiology - etiology - pathology
Pregnancy
Pregnancy Complications - epidemiology - etiology
Premature Birth - metabolism
Prospective Studies
Questionnaires
Risk factors
Vitamin D - administration & dosage
Abstract
There has been a thrilling development , as well as profound changes, in our understanding of the effect of fetal nutrition on the development and health of the child. The Norwegian Mother and Child Cohort Study (MoBa) is an ongoing nationwide population-based pregnancy cohort study that between 1999 and 2008 recruited 90,723 women with 106,981 pregnancies and 108,487 children. The objective of MoBa is to test specific etiologic hypotheses by estimating the association between exposures and diseases with a special focus on disorders that may originate in early life. An important aspect in this regard is maternal diet and nutritional status during pregnancy. Nutritional factors have long been considered to be important determinants of maternal and fetal health, and dietary information is currently being collected in a number of pregnancy cohorts in Europe and the United States. Thus far, pregnancy complications studied in MoBa are preterm birth, preeclampsia, and fetal growth; and the aim of this article is to report results of recently published studies of dietary factors in relation to these outcomes. Numerous studies are planned using MoBa data, and the aim is to add to the knowledge of the interplay between dietary factors, nonnutrients, and toxic dietary substances and epigenetic modulation on fetal development and health later in life.
Notes
Cites: J Clin Endocrinol Metab. 2007 Sep;92(9):3517-2217535985
Cites: Am J Obstet Gynecol. 2001 Aug;185(2):451-811518908
Cites: Matern Child Nutr. 2008 Jan;4(1):14-2718171404
Cites: Matern Child Nutr. 2008 Jan;4(1):28-4318171405
Cites: Environ Health. 2007;6:3317958907
Cites: Acta Obstet Gynecol Scand. 2008;87(3):319-2418307072
Cites: Arch Dis Child. 2009 Mar;94(3):180-419052032
Cites: Eur J Clin Nutr. 2009 Mar;63(3):347-5418059417
Cites: J Nutr. 2009 Jun;139(6):1162-819369368
Cites: Epidemiology. 2009 Sep;20(5):720-619451820
Cites: Am J Epidemiol. 2009 Dec 15;170(12):1486-9319880541
Cites: Public Health Nutr. 2010 Jan;13(1):54-6219490733
Cites: Acta Obstet Gynecol Scand. 2000 Jun;79(6):435-910857866
Cites: Public Health Nutr. 2001 Apr;4(2B):611-2411683554
Cites: Environ Health Perspect. 2003 Apr;111(4):637-4112676628
Cites: J Nutr. 2003 May;133(5 Suppl 2):1684S-1692S12730485
Cites: J Soc Gynecol Investig. 2004 Jul;11(5):263-7115219879
Cites: Nutr Rev. 1994 Mar;52(3):84-948015751
Cites: Am J Clin Nutr. 1995 Jun;61(6 Suppl):1402S-1406S7754995
Cites: Reprod Fertil Dev. 2005;17(3):341-815745642
Cites: Am J Obstet Gynecol. 2005 Oct;193(4):1292-30116202717
Cites: JAMA. 2006 Oct 18;296(15):1885-9917047219
Cites: Int J Epidemiol. 2006 Oct;35(5):1146-5016926217
Cites: Eur J Epidemiol. 2006;21(10):749-5817111251
Cites: Ann Nutr Metab. 2007;51(2):146-5417536192
Cites: Public Health Nutr. 2007 Aug;10(8):838-4717493318
Cites: Ann Epidemiol. 2007 Sep;17(9):663-817521921
Cites: Am J Epidemiol. 2007 Sep 15;166(6):687-9617631607
Cites: J Nutr. 2010 Mar;140(3):572-920089778
Cites: Environ Int. 2007 Nov;33(8):1057-6217643489
PubMed ID
21543541 View in PubMed
Less detail

Environmental barriers, person-environment fit and mortality among community-dwelling very old people.

https://arctichealth.org/en/permalink/ahliterature265500
Source
BMC Public Health. 2013;13:783
Publication Type
Article
Date
2013
Author
Merja Rantakokko
Timo Törmäkangas
Taina Rantanen
Maria Haak
Susanne Iwarsson
Source
BMC Public Health. 2013;13:783
Date
2013
Language
English
Publication Type
Article
Keywords
Aged, 80 and over
Architectural Accessibility
Environment
Female
Frail Elderly
Housing for the Elderly
Humans
Male
Mobility Limitation
Mortality - trends
Proportional Hazards Models
Sweden - epidemiology
Abstract
Environmental barriers are associated with disability-related outcomes in older people but little is known of the effect of environmental barriers on mortality. The aim of this study was to examine whether objectively measured barriers in the outdoor, entrance and indoor environments are associated with mortality among community-dwelling 80- to 89-year-old single-living people.
This longitudinal study is based on a sample of 397 people who were single-living in ordinary housing in Sweden. Participants were interviewed during 2002-2003, and 393 were followed up for mortality until May 15, 2012.Environmental barriers and functional limitations were assessed with the Housing Enabler instrument, which is intended for objective assessments of Person-Environment (P-E) fit problems in housing and the immediate outdoor environment. Mortality data were gathered from the public national register. Cox regression models were used for the analyses.
A total of 264 (67%) participants died during follow-up. Functional limitations increased mortality risk. Among the specific environmental barriers that generate the most P-E fit problems, lack of handrails in stairs at entrances was associated with the highest mortality risk (adjusted RR 1.55, 95% CI 1.14-2.10), whereas the total number of environmental barriers at entrances and outdoors was not associated with mortality. A higher number of environmental barriers indoors showed a slight protective effect against mortality even after adjustment for functional limitations (RR 0.98, 95% CI 0.96-1.00).
Specific environmental problems may increase mortality risk among very-old single-living people. However, the association may be confounded by individuals' health status which is difficult to fully control for. Further studies are called for.
Notes
Cites: Am Heart J. 2011 May;161(5):950-521570528
Cites: J Psychiatr Res. 1975 Nov;12(3):189-981202204
Cites: Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):3-821621282
Cites: Age Ageing. 2012 Jan;41(1):118-2122086965
Cites: Arch Phys Med Rehabil. 2012 Sep;93(9):1609-1622484216
Cites: Age Ageing. 2003 Nov;32(6):619-2514600003
Cites: Aging Clin Exp Res. 2013 Dec;25(6):667-7524136449
Cites: J Psychiatr Res. 1982-1983;17(1):37-497183759
Cites: J Epidemiol Community Health. 1993 Aug;47(4):298-3028228766
Cites: BMJ. 1998 Sep 19;317(7161):802-89740574
Cites: Lancet. 2005 Nov 26;366(9500):1885-9316310556
Cites: Scand J Occup Ther. 2005 Mar;12(1):29-3916389996
Cites: J Epidemiol. 2006 Nov;16(6):261-7017085876
Cites: Gerontologist. 2007 Feb;47(1):78-8417327543
Cites: Gerontologist. 2007 Feb;47(1):96-10717327545
Cites: Arch Gerontol Geriatr. 2007 Nov-Dec;45(3):233-4217296237
Cites: Aust J Rural Health. 2008 Feb;16(1):5-1118186716
Cites: Prev Med. 2000 Jul;31(1):15-2210896840
Cites: Am J Epidemiol. 2002 Mar 15;155(6):507-1511882524
Cites: J Epidemiol Community Health. 2002 Dec;56(12):913-812461111
Cites: Aging Clin Exp Res. 2003 Apr;15(2):174-8312889850
Cites: Am J Epidemiol. 2008 Jan 15;167(2):240-817906296
Cites: Gerontologist. 2009 Jun;49(3):355-6719420315
Cites: J Aging Phys Act. 2006 Apr;14(2):203-1119462550
Cites: Clin Rehabil. 2009 Jun;23(6):558-6719403554
Cites: Soc Sci Med. 2009 Sep;69(5):754-6019604611
Cites: Soc Sci Med. 2009 Sep;69(6):964-7019643522
Cites: Int J Public Health. 2010 Feb;55(1):59-6919768384
Cites: J Am Geriatr Soc. 2010 Oct;58(10):1925-3020831722
Cites: J Am Geriatr Soc. 2010 Dec;58(12):2358-6221087220
Cites: J Urban Health. 2011 Feb;88(1):154-6721274644
Cites: Int J Sports Med. 2011 Mar;32(3):216-2221165808
Cites: J Aging Phys Act. 2011 Apr;19(2):117-3621558567
Cites: Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):55-6021420181
PubMed ID
23981906 View in PubMed
Less detail

Exploration of biomarkers for total fish intake in pregnant Norwegian women.

https://arctichealth.org/en/permalink/ahliterature98999
Source
Public Health Nutr. 2010 Jan;13(1):54-62
Publication Type
Article
Date
Jan-2010
Author
Anne Lise Brantsaeter
Margaretha Haugen
Yngvar Thomassen
Dag G Ellingsen
Trond A Ydersbond
Tor-Arne Hagve
Jan Alexander
Helle Margrete Meltzer
Author Affiliation
Division of Environmental Medicine, Department of Food Safety and Nutrition, Norwegian Institute of Public Health, PO Box 4404 Nydalen, NO-04030 Oslo, Norway. anne.lise.brantsaeter@fhi.no
Source
Public Health Nutr. 2010 Jan;13(1):54-62
Date
Jan-2010
Language
English
Geographic Location
Norway
Publication Type
Article
Keywords
Adult
Arsenic - administration & dosage - blood
Biological Markers - blood - urine
Cohort Studies
Diet Records
Erythrocytes - chemistry
Fatty Acids, Omega-3 - administration & dosage - analysis
Female
Food Habits
Humans
Iodine - administration & dosage - urine
Mercury - administration & dosage - blood
Norway
Pregnancy
Questionnaires
Seafood - analysis
Selenium - administration & dosage - blood
Young Adult
Abstract
OBJECTIVE: Few biomarkers for dietary intake of various food groups have been established. The aim of the present study was to explore whether selenium (Se), iodine, mercury (Hg) or arsenic may serve as a biomarker for total fish and seafood intake in addition to the traditionally used n-3 fatty acids EPA and DHA. DESIGN: Intake of fish and seafood estimated by an FFQ was compared with intake assessed by a 4 d weighed food diary and with biomarkers in blood and urine. SETTING: Validation study in the Norwegian Mother and Child Cohort Study (MoBa). SUBJECTS: One hundred and nineteen women. RESULTS: Total fish/seafood intake (median 39 g/d) calculated with the MoBa FFQ was comparable to intake calculated by the food diary (median 30 g/d, rS = 0.37, P
Notes
RefSource: Public Health Nutr. 2009 Dec;12(12):2536-7
PubMed ID
19490733 View in PubMed
Less detail

Fear of moving outdoors and development of outdoor walking difficulty in older people.

https://arctichealth.org/en/permalink/ahliterature151341
Source
J Am Geriatr Soc. 2009 Apr;57(4):634-40
Publication Type
Article
Date
Apr-2009
Author
Merja Rantakokko
Minna Mänty
Susanne Iwarsson
Timo Törmäkangas
Raija Leinonen
Eino Heikkinen
Taina Rantanen
Author Affiliation
Department of Health Sciences, Finnish Centre for Interdisciplinary Gerontology, University of Jyväskylä, Jyväskylä, Finland. merja.rantakokko@sport.jyu.fi
Source
J Am Geriatr Soc. 2009 Apr;57(4):634-40
Date
Apr-2009
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Chi-Square Distribution
Cross-Sectional Studies
Environment
Fear
Female
Finland
Geriatric Assessment
Humans
Interviews as Topic
Logistic Models
Male
Mobility Limitation
Musculoskeletal Diseases - complications
Prospective Studies
Residence Characteristics
Risk factors
Socioeconomic Factors
Abstract
To study which individual characteristics and environmental factors correlate with fear of moving outdoors and whether fear of moving outdoors predicts development of mobility limitation.
Observational prospective cohort study and cross-sectional analyses.
Community and research center.
Seven hundred twenty-seven community-living people aged 75 to 81 were interviewed at baseline, of whom 314 took part in a 3.5-year follow-up.
Fear of moving outdoors and its potential individual and environmental correlates were assessed at baseline. Perceived difficulties in walking 0.5 km and 2 km were assessed twice a year over a 3.5-year period.
At baseline, 65% of the women and 29% of the men reported fear of moving outdoors. Poor socioeconomic status; musculoskeletal diseases; slow walking speed; and the presence of poor street conditions, hills in the nearby environment, and noisy traffic correlated with fear of moving outdoors. At the first 6-month follow-up, participants with fear of moving outdoors had more than four times the adjusted risk (odds ratio (OR)=4.6, 95% confidence interval (CI)=1.92-11.00) of developing difficulties in walking 0.5 km and a three times greater adjusted risk (OR=3.10, 95% CI=1.49-6.46) for developing difficulty in walking 2 km compared with those without fear. The difference in the prevalence of walking difficulties remained statistically significant over the 3.5-year follow-up (P=.02 and P=.009, respectively).
Fear of moving outdoors is common in older adults and increases the risk of developing self-reported difficulties in walking 0.5 km and 2 km. Knowledge about individual and environmental factors underlying fear of moving outdoors and finding ways to alleviate fear of moving outdoors are important for community planning and prevention of disability.
PubMed ID
19392955 View in PubMed
Less detail

Fish liver and seagull eggs, vitamin D-rich foods with a shadow: results from the Norwegian Fish and Game Study.

https://arctichealth.org/en/permalink/ahliterature127159
Source
Mol Nutr Food Res. 2012 Mar;56(3):388-98
Publication Type
Article
Date
Mar-2012
Author
Bryndis E Birgisdottir
Anne L Brantsaeter
Helen E Kvalem
Helle K Knutsen
Margaretha Haugen
Jan Alexander
Ragna B Hetland
Lage Aksnes
Helle M Meltzer
Author Affiliation
Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway. bryndis.eva.birgisdottir@fhi.no
Source
Mol Nutr Food Res. 2012 Mar;56(3):388-98
Date
Mar-2012
Language
English
Publication Type
Article
Keywords
Adult
Aged
Animals
Charadriiformes
Databases, Factual
Diet
Dioxins - analysis - metabolism - toxicity
Eggs
Female
Fish Oils - administration & dosage
Fishes
Food contamination - analysis
Humans
Liver - chemistry
Male
Middle Aged
Norway
Polychlorinated Biphenyls - analysis - metabolism - toxicity
Questionnaires
Vitamin D - administration & dosage - analysis
Vitamins - administration & dosage - analysis
Abstract
Fish liver, fish liver oil, oily fish and seagull eggs have been major sources of vitamin D for the coastal population of Norway. They also provide dioxin and polychlorinated dioxin-like compounds (dl-compounds), which may interfere with vitamin D homeostasis. We investigated whether serum 25-hydroxyvitamin D (25(OH)D) might be compromised by concomitant intake of dl-compounds.
We studied 182 adults participating in the Norwegian Fish and Game Study. Participants who consumed fish liver and/or seagull eggs had higher dl-compound intake and blood concentrations than non-consumers (p
PubMed ID
22319024 View in PubMed
Less detail

The genetic and environmental effects on depressive symptoms among older female twins.

https://arctichealth.org/en/permalink/ahliterature176906
Source
Twin Res. 2004 Dec;7(6):626-36
Publication Type
Article
Date
Dec-2004
Author
Sanna Takkinen
Asko Tolvanen
Jaakko Kaprio
Stig Berg
Markku Koskenvuo
Taina Rantanen
Author Affiliation
Institute of Gerontology, School of Health Sciences, Jönköping, Sweden.
Source
Twin Res. 2004 Dec;7(6):626-36
Date
Dec-2004
Language
English
Publication Type
Article
Keywords
Aged
Cross-Sectional Studies
Depression - epidemiology - genetics - psychology
Environment
Female
Finland - epidemiology
Humans
Models, Biological
Risk factors
Twins - genetics - psychology
Twins, Dizygotic - genetics - psychology
Twins, Monozygotic - genetics - psychology
Abstract
The aim of the present study was to examine the contribution of genetic and environmental factors to depressive symptoms among older women. The participants were 102 monozygotic and 115 dizygotic female twin pairs aged 64 to 76 years. Depressive symptoms were assessed by the Center for the Epidemiologic Studies Depression Scale. The contribution of genetic and environmental effects was estimated for the constructed depressiveness factor and for the subscales which were depressed mood, psychomotor retardation, lack of wellbeing and interpersonal difficulties. Of the variance in depressiveness, shared environmental influences accounted for 39% and nonshared environmental influences 61%. For the subscales, 24% to 62% of the variance was explained by individual, and 13% to 23% by shared, environmental factors. Lack of wellbeing had its own moderate additive genetic effect explaining 30% of the variance. This study showed that in older women predominantly environmental factors underlay individual differences in depressiveness; however, the factors varied to some extent between dimensions measured by the subscales.
PubMed ID
15607014 View in PubMed
Less detail

Genetic and environmental influences on hearing at different frequencies separately for the better and worse hearing ear in older women.

https://arctichealth.org/en/permalink/ahliterature160056
Source
Int J Audiol. 2007 Dec;46(12):772-9
Publication Type
Article
Date
Dec-2007
Author
Anne Viljanen
Jaakko Kaprio
Ilmari Pyykkö
Martti Sorri
Markku Kauppinen
Markku Koskenvuo
Taina Rantanen
Author Affiliation
Finnish Centre for Interdisciplinary Gerontology, Department of Health Sciences, University of Jyväskylä, Finland. anne.viljanen@sport.jyu.fi
Source
Int J Audiol. 2007 Dec;46(12):772-9
Date
Dec-2007
Language
English
Publication Type
Article
Keywords
Aged
Aging - physiology
Auditory Threshold - physiology
Diseases in Twins - epidemiology
Environmental Exposure - adverse effects
Female
Finland - epidemiology
Hearing Disorders - epidemiology - etiology - genetics
Humans
Middle Aged
Registries
Severity of Illness Index
Twins, Dizygotic
Abstract
The purpose of the present study was to examine the relative contribution of genetic and environmental effects on the air-conducted hearing threshold levels at low (0.125-0.5 kHz), mid (1-2 kHz), and high (4-8 kHz) frequencies separately for the better and worse hearing ear in older women. We also examined the distribution of audiogram configurations. Data was analysed using quantitative genetic modelling. As part of the Finnish twin study on aging (FITSA), hearing was measured in 103 monozygotic and 114 dizygotic female twin pairs aged 63-76 years. Approximately every third subject had a flat type, and two-thirds a descending type of audiogram configuration. No significant difference was observed in the distribution of audiogram configurations between zygosity groups. In the better ear, additive genetic effects accounted for 64%-74% of the total variance at different frequencies. For the worse ear, environmental effects were larger. Although overall heritability is rather constant across the frequency spectrum, it is noteworthy that at low and high frequencies frequency-specific genetic and environmental effects together accounted for the majority of the total variance.
PubMed ID
18049966 View in PubMed
Less detail

Genetic influences on resting electrocardiographic variables in older women: a twin study.

https://arctichealth.org/en/permalink/ahliterature153101
Source
Ann Noninvasive Electrocardiol. 2009 Jan;14(1):57-64
Publication Type
Article
Date
Jan-2009
Author
Sara Mutikainen
Alfredo Ortega-Alonso
Markku Alén
Jaakko Kaprio
Jouko Karjalainen
Taina Rantanen
Urho M Kujala
Author Affiliation
Department of Health Sciences, University of Jyväskylä, Finland. sara.mutikainen@gmail.com
Source
Ann Noninvasive Electrocardiol. 2009 Jan;14(1):57-64
Date
Jan-2009
Language
English
Publication Type
Article
Keywords
Aged
Aging - genetics
Cohort Studies
Confidence Intervals
Electrocardiography
Female
Finland
Genetic Predisposition to Disease
Heart rate - genetics
Humans
Middle Aged
Reference Values
Rest
Twins
Twins, Dizygotic
Twins, Monozygotic
Abstract
Previous studies in young and middle-aged men and women have shown that resting electrocardiographic (ECG) variables are influenced by genetic factors. However, the extent to which resting ECG variables are influenced by genetic factors in older women is unknown. Thus, the aim of this study was to estimate the relative contribution of genetic and environmental influences to individual differences in resting ECG variables among older female twins without overt cardiac diseases.
Resting ECG recordings were obtained from 186 monozygotic and 203 dizygotic twin individuals, aged 63-76 years. Quantitative genetic modeling was used to decompose the phenotypic variance in each resting ECG variable into additive genetic, dominance genetic, shared environmental, and unique environmental influences.
The results showed that individual differences in the majority of the resting ECG variables were moderately to highly explained by additive genetic influences, ranging from 32% for T axis to 72% for TV(5). The results also suggested dominance genetic influences on QRS duration, TV(1), and Sokolow-Lyon voltage (36%, 53%, and 57%, respectively). Unique environmental influences were important for each resting ECG variable, whereas shared environmental influences were detected only for QT interval and QTc.
In older women without overt cardiac diseases, genetic influences explain a moderate to high proportion of individual differences in the majority of the resting ECG variables. Genetic influences are especially strong for T-wave amplitudes, left ventricular mass, and hypertrophy indices, whereas other variables, including heart rate, intervals, and axes, are more affected by environmental influences.
PubMed ID
19149794 View in PubMed
Less detail

Genetic influences underlying self-rated health in older female twins.

https://arctichealth.org/en/permalink/ahliterature174438
Source
J Am Geriatr Soc. 2005 Jun;53(6):1002-7
Publication Type
Article
Date
Jun-2005
Author
Raija Leinonen
Jaakko Kaprio
Marja Jylhä
Asko Tolvanen
Markku Koskenvuo
Eino Heikkinen
Taina Rantanen
Author Affiliation
Finnish Center for Interdisciplinary Gerontology, Department of Health Sciences, University of Jyväskylaä, Finland. raija.leinonen@sport.jyu.fi
Source
J Am Geriatr Soc. 2005 Jun;53(6):1002-7
Date
Jun-2005
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Aged
Cross-Sectional Studies
Depression - epidemiology
Diseases in Twins - epidemiology
Environment
Female
Finland - epidemiology
Health status
Humans
Logistic Models
Mental health
Middle Aged
Multivariate Analysis
Self Concept
Twins - genetics
Walking
Abstract
To examine the genetic and environmental sources of variation in self-rated health (SRH) in older female twins and to explore the roles of morbidity, functional limitation, and psychological well-being as mediators of genetic and environmental effects on SRH.
Cross-sectional analysis of twin data.
Research laboratory.
One hundred two monozygotic and 115 dizygotic female twin pairs aged 63 to 76.
SRH was categorized as good, average, or poor. Morbidity was described using a physician-assessed disease-severity scale together with information about the presence of diabetes mellitus and cancer. Maximal walking speed measured over 10 m was used to assess physical functional limitation; the Mini-Mental State Examination and the Center for Epidemiologic Studies Depression Scale were used to characterize psychological well-being. The contributions of genetic and environmental (defined as familial (shared by siblings) or nonshared (unique to each sibling)) effects were assessed using univariate and multivariate structural equation modeling of twin data.
SRH did not have its own specific genetic effect but shared a genetic component in common with the genetic components underlying liability to disease severity, maximal walking speed, and depressive symptoms. It accounted for 64% of the variation in SRH, with environmental effects accounting for the remaining variation.
The current results suggest that there are no specific genetic effects on SRH but rather that genetic influences on SRH are mediated through genetic influences affecting chronic diseases, functional limitation, and mood.
PubMed ID
15935024 View in PubMed
Less detail

Hearing as a predictor of falls and postural balance in older female twins.

https://arctichealth.org/en/permalink/ahliterature152870
Source
J Gerontol A Biol Sci Med Sci. 2009 Feb;64(2):312-7
Publication Type
Article
Date
Feb-2009
Author
Anne Viljanen
Jaakko Kaprio
Ilmari Pyykkö
Martti Sorri
Satu Pajala
Markku Kauppinen
Markku Koskenvuo
Taina Rantanen
Author Affiliation
Department of Health Sciences, Finnish Centre for Interdisciplinary Gerontology, Finland. anne.viljanen@sport.jyu.fi
Source
J Gerontol A Biol Sci Med Sci. 2009 Feb;64(2):312-7
Date
Feb-2009
Language
English
Publication Type
Article
Keywords
Accidental Falls - statistics & numerical data
Aged
Aging - genetics - physiology
Audiometry
Confidence Intervals
Female
Finland
Hearing - genetics
Hearing Loss - diagnosis - epidemiology - genetics
Humans
Incidence
Middle Aged
Postural Balance - physiology
Predictive value of tests
Risk assessment
Sampling Studies
Sensitivity and specificity
Twins
Twins, Dizygotic
Twins, Monozygotic
Abstract
The purpose of the present study was to examine, first, whether hearing acuity predicts falls and whether the potential association is explained by postural balance and, second, to examine whether shared genetic or environmental effects underlie these associations.
Hearing was measured using a clinical audiometer as a part of the Finnish Twin Study on Aging in 103 monozygotic and 114 dizygotic female twin pairs aged 63-76 years. Postural balance was indicated as a center of pressure (COP) movement in semi-tandem stance, and participants filled in a fall-calendar daily for an average of 345 days after the baseline.
Mean hearing acuity (better ear hearing threshold level at 0.5-4 kHz) was 21 dB (standard deviation [SD] 12). Means of the COP velocity moment for the best to the poorest hearing quartiles increased linearly from 40.7 mm(2)/s (SD 24.4) to 52.8 mm(2)/s (SD 32.0) (p value for the trend = .003). Altogether 199 participants reported 437 falls. Age-adjusted incidence rate ratios (IRRs) for falls, with the best hearing quartile as a reference, were 1.2 (95% confidence interval [CI] = 0.4-3.8) in the second, 4.1 (95% CI = 1.1-15.6) in the third, and 3.4 (95% CI = 1.0-11.4) in the poorest hearing quartiles. Adjustment for COP velocity moment decreased IRRs markedly. Twin analyses showed that the association between hearing acuity and postural balance was not explained by genetic factors in common for these traits.
People with poor hearing acuity have a higher risk for falls, which is partially explained by their poorer postural control. Auditory information about environment may be important for safe mobility.
Notes
Cites: Am J Otolaryngol. 1999 Nov-Dec;20(6):371-810609481
Cites: J Gerontol A Biol Sci Med Sci. 2008 Feb;63(2):171-818314453
Cites: Gait Posture. 2002 Aug;16(1):1-1412127181
Cites: Arch Neurol. 2003 Jun;60(6):835-912810488
Cites: J Clin Epidemiol. 2003 Jul;56(7):659-6812921935
Cites: J Appl Physiol (1985). 2004 Jan;96(1):308-1512959956
Cites: Ann Epidemiol. 2004 May;14(5):311-815177269
Cites: Acta Otolaryngol. 1973 Aug-Sep;76(2):208-204543916
Cites: J Psychiatr Res. 1975 Nov;12(3):189-981202204
Cites: Prog Clin Biol Res. 1978;24 Pt B:179-84569306
Cites: Dan Med Bull. 1987 Apr;34 Suppl 4:1-243595217
Cites: Lancet. 1987 Aug 1;2(8553):261-42886727
Cites: Age Ageing. 1989 Jan;18(1):31-42711920
Cites: Br J Ind Med. 1992 Feb;49(2):138-411536822
Cites: Ann Otol Rhinol Laryngol. 1993 Jan;102(1 Pt 2):1-168420477
Cites: J Gerontol. 1994 Mar;49(2):M72-848126355
Cites: J Gerontol A Biol Sci Med Sci. 1996 Mar;51(2):M53-638612104
Cites: Br J Audiol. 1999 Feb;33(1):53-910219722
Cites: Curr Opin Otolaryngol Head Neck Surg. 2005 Dec;13(6):343-816282762
Cites: Lancet. 2005 Nov 26;366(9500):1885-9316310556
Cites: J Am Geriatr Soc. 2006 Apr;54(4):613-816686871
Cites: Am J Epidemiol. 2006 Aug 1;164(3):246-5616731575
Cites: Tohoku J Exp Med. 2006 Aug;209(4):291-30116864951
Cites: Age Ageing. 2006 Sep;35 Suppl 2:ii7-ii1116926210
Cites: Curr Pharm Des. 2007;13(1):119-2617266591
Cites: J Gerontol A Biol Sci Med Sci. 2007 Apr;62(4):447-5217452741
Cites: J Gerontol A Biol Sci Med Sci. 2007 Nov;62(11):1294-918000151
Cites: Int J Audiol. 2007 Dec;46(12):772-918049966
Cites: J Gerontol A Biol Sci Med Sci. 2000 Jan;55(1):M10-610719767
PubMed ID
19182227 View in PubMed
Less detail

Individual and environmental factors underlying life space of older people - study protocol and design of a cohort study on life-space mobility in old age (LISPE).

https://arctichealth.org/en/permalink/ahliterature118779
Source
BMC Public Health. 2012;12:1018
Publication Type
Article
Date
2012
Author
Taina Rantanen
Erja Portegijs
Anne Viljanen
Johanna Eronen
Milla Saajanaho
Li-Tang Tsai
Markku Kauppinen
Eeva-Maija Palonen
Sarianna Sipilä
Susanne Iwarsson
Merja Rantakokko
Author Affiliation
Gerontology Research Center and Department of Health Sciences, University of Jyväskylä, P,O,Box 35, Jyväskylä, FI-40014, Finland. taina.rantanen@jyu.fi
Source
BMC Public Health. 2012;12:1018
Date
2012
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Aged
Aged, 80 and over
Aging
Cohort Studies
Female
Finland
Humans
Male
Quality of Life
Walking
Abstract
A crucial issue for the sustainability of societies is how to maintain health and functioning in older people. With increasing age, losses in vision, hearing, balance, mobility and cognitive capacity render older people particularly exposed to environmental barriers. A central building block of human functioning is walking. Walking difficulties may start to develop in midlife and become increasingly prevalent with age. Life-space mobility reflects actual mobility performance by taking into account the balance between older adults internal physiologic capacity and the external challenges they encounter in daily life. The aim of the Life-Space Mobility in Old Age (LISPE) project is to examine how home and neighborhood characteristics influence people's health, functioning, disability, quality of life and life-space mobility in the context of aging. In addition, examine whether a person's health and function influence life-space mobility.
This paper describes the study protocol of the LISPE project, which is a 2-year prospective cohort study of community-dwelling older people aged 75 to 90 (n?=?848). The data consists of a baseline survey including face-to-face interviews, objective observation of the home environment and a physical performance test in the participant's home. All the baseline participants will be interviewed over the phone one and two years after baseline to collect data on life-space mobility, disability and participation restriction. Additional home interviews and environmental evaluations will be conducted for those who relocate during the study period. Data on mortality and health service use will be collected from national registers. In a substudy on walking activity and life space, 358 participants kept a 7-day diary and, in addition, 176 participants also wore an accelerometer.
Our study, which includes extensive data collection with a large sample, provides a unique opportunity to study topics of importance for aging societies. A novel approach is employed which enables us to study the interactions of environmental features and individual characteristics underlying the life-space of older people. Potentially, the results of this study will contribute to improvements in strategies to postpone or prevent progression to disability and loss of independence.
Notes
Cites: Arch Phys Med Rehabil. 2001 Feb;82(2):210-611239312
Cites: J Psychiatr Res. 1975 Nov;12(3):189-981202204
Cites: Am J Epidemiol. 2002 Mar 15;155(6):507-1511882524
Cites: Psychol Aging. 2002 Dec;17(4):539-4712507352
Cites: J Am Geriatr Soc. 2003 Mar;51(3):393-812588584
Cites: J Am Geriatr Soc. 2003 Nov;51(11):1610-414687391
Cites: Gerontologist. 1969 Autumn;9(3):179-865349366
Cites: Age Ageing. 2009 Mar;38(2):162-719008307
Cites: J Gerontol A Biol Sci Med Sci. 2009 Feb;64(2):312-719182227
Cites: J Am Geriatr Soc. 2009 Apr;57(4):634-4019392955
Cites: J Am Geriatr Soc. 2009 Apr;57(4):722-919220562
Cites: Gerontologist. 2009 Jun;49(3):355-6719420315
Cites: Maturitas. 2009 Sep 20;64(1):14-919695800
Cites: Age Ageing. 2009 Nov;38(6):757-6119779051
Cites: J Am Geriatr Soc. 2009 Dec;57(12):2282-619874410
Cites: J Am Geriatr Soc. 2010 Apr;58(4):707-1220398151
Cites: Milbank Mem Fund Q Health Soc. 1976 Fall;54(4):439-67137366
Cites: Int J Aging Hum Dev. 1983;16(3):209-196852966
Cites: Acta Med Scand Suppl. 1986;711:233-73535411
Cites: J Am Geriatr Soc. 1990 Dec;38(12):1311-52254569
Cites: J Gerontol. 1994 Mar;49(2):M85-948126356
Cites: Soc Sci Med. 1994 Jan;38(1):1-148146699
Cites: Psychol Med. 1997 Jan;27(1):231-59122304
Cites: Scand J Soc Med Suppl. 1997;52:1-659241696
Cites: Psychol Med. 1998 May;28(3):551-89626712
Cites: JAMA. 1963 Sep 21;185:914-914044222
Cites: Phys Ther. 2005 Oct;85(10):1008-11916180950
Cites: Aging Ment Health. 2005 Nov;9(6):526-3416214700
Cites: Int J Audiol. 2005 Sep;44(9):500-816238180
Cites: Ophthalmology. 2005 Dec;112(12):2227-3716325714
Cites: J Aging Phys Act. 2007 Jan;15(1):90-10217387231
Cites: Scand J Med Sci Sports. 2007 Apr;17(2):156-6417394477
Cites: Eur J Appl Physiol. 2007 Jul;100(5):581-917063361
Cites: Arch Phys Med Rehabil. 2007 Sep;88(9):1108-1317826454
Cites: Lancet. 2007 Oct 20;370(9596):1453-718064739
Cites: Arch Phys Med Rehabil. 2010 May;91(5):765-7320434615
Cites: Bull World Health Organ. 2010 Feb;88(2):131-820428370
Cites: J Gerontol A Biol Sci Med Sci. 2008 Jan;63(1):67-7518245763
Cites: Arch Gerontol Geriatr. 2010 Nov-Dec;51(3):e133-820932457
Cites: Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):55-6021420181
Cites: Age Ageing. 2012 Jan;41(1):118-2122086965
Cites: Am J Public Health. 2012 Aug;102(8):1508-1522698013
Cites: J Gerontol A Biol Sci Med Sci. 2012 Nov;67(11):1230-722546957
Cites: J Gerontol B Psychol Sci Soc Sci. 2012 Nov;67(6):765-7422929396
Cites: Can J Aging. 2011 Mar;30(1):7-1921401978
Cites: Age Ageing. 2001 Nov;30(6):489-9411742778
PubMed ID
23170987 View in PubMed
Less detail

Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort study.

https://arctichealth.org/en/permalink/ahliterature296615
Source
BMJ Open. 2018 04 23; 8(3):e018895
Publication Type
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Date
04-23-2018
Author
Eleni Papadopoulou
Jérémie Botton
Anne-Lise Brantsæter
Margaretha Haugen
Jan Alexander
Helle Margrete Meltzer
Jonas Bacelis
Anders Elfvin
Bo Jacobsson
Verena Sengpiel
Author Affiliation
Division of Infection Control and Environmental Health, Department of Environmental Exposure and Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.
Source
BMJ Open. 2018 04 23; 8(3):e018895
Date
04-23-2018
Language
English
Publication Type
Journal Article
Observational Study
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Keywords
Caffeine - administration & dosage - adverse effects
Child
Child Development - drug effects
Child, Preschool
Cohort Studies
Diet Records
Eating
Female
Humans
Infant
Infant, Newborn
Norway
Overweight - chemically induced - etiology
Pregnancy
Prenatal Exposure Delayed Effects - chemically induced - etiology
Prospective Studies
Risk factors
Weight Gain
Abstract
To study the association between maternal caffeine intake during pregnancy and the child's weight gain and overweight risk up to 8 years.
Prospective nationwide pregnancy cohort.
The Norwegian Mother and Child Cohort Study.
A total of 50?943 mothers recruited from 2002 to 2008 and their children, after singleton pregnancies, with information about average caffeine intake assessed at mid-pregnancy.
Child's body size information at 11 age points from 6 weeks to 8 years. We defined excess growth in infancy as a WHO weight gain z-score of >0.67 from birth to age 1?year, and overweight according to the International Obesity Task Force. We used a growth model to assess individual growth trajectories.
Compared with pregnant women with low caffeine intake (200?mg/day had consistently higher weight. Very high caffeine exposures were associated with higher weight gain velocity from infancy to age 8 years.
Any caffeine consumption during pregnancy is associated with a higher risk of excess infant growth and of childhood overweight, mainly at preschool ages. Maternal caffeine intake may modify the overall weight growth trajectory of the child from birth to 8 years. This study adds supporting evidence for the current advice to reduce caffeine intake during pregnancy.
PubMed ID
29685923 View in PubMed
Less detail

41 records – page 1 of 3.