Examination of radiosafety effect of the new nutrition compositions were carried out in the experiments. The immunomodifying influence of this products were established. It is shown the possibility of their addition to the ration of population from the polluted territory.
Epidemiological investigation of spontaneous abortions and congenital anomalies in three towns of Ukraine has shown that mutation rate in Mariupol, the most contaminated town, as compared with relatively clean town is essentially higher. Genetical consequences due to environmental chemical pollution in Mariupol proved to be equivalent to the chronic influence of ionizing radiation for 30 years in the dose of 230 REM.
The levels of vitamins in the blood of persons who suffered from the catastrophe at Chernobyl NPP subject to medically treatment at Kiev clinics at different time periods have been studied. Polyhypovitaminosis has been detected in all the patients groups examined, especially in persons with the diagnosis of acute radiation sickness. The hypovitaminosis status in the organism is regulated by means of an adequate vitamin therapy. The scientifically substantiated vitamin therapy and vitamin prophylaxis are proposed to be performed for the population of Ukraine affected by the consequences of the Chernobyl catastrophe.
Effects were studied of bottled mineral water "Zbruch Naftusia" on the blood and immunity condition of hypothetically healthy population of the Donetsk region living under environmental hazard conditions and having disorders in the area of the immune system. The studies made showed that prescription of the above drug preparation for use by conditionally healthy population of the Donetsk region, just those very contingents maintaining long-time occupational contact with liquidators of aftermath of the Chernobyl breakdown, is associated with immunocorrection at the level of content of the immunocompetent cell populations and subpopulations, with their function restored against the background of alleviating of the syndrome of endogenous intoxication that had developed because of them being resident under health hazard conditions in an ecocrisis-ridden region.
An analysis of state of health among people living in Kiev over 1985-2000 was carried out. It is determined that birth rate decreases and mortality increases constantly. Life expectancy decreased too. Substantial and steady tendency of rising most of diseases is observed in the city. Diseases of cardiovascular system, thyroid gland, digestive system, urogenital system and different neoplasm are diagnosed nowadays more frequently than earlier. Children population presents with more increasing respiratory diseases, illnesses of organs of sense, nervous system, digestive system and blood as well as social diseases. Atmosphere is polluted with aromatic and saturated hydrocarbons, carbon oxide, nitric oxide, 3-4-benzpyrene, sulphurous anhydrides. The article presents data concerning negative tendency in demographic situation and the population's state of health in Kiev and air pollution. All above mentioned necessitate to develop well-founded adequate prophylactic measures to improve the situation.
The qualitative distinction of the new class of virus-based biopesticides from chemicals is the intracellular parasitism of the active agent in the organisms of the living biological host, its capacity to join natural microbiocenoses and to restrain the number of the destructive species over a long period of time. Thus, the program of the study of harmlessness of entomopathogenic viruses must be aimed at preventing the possibility of their adaptation to non-target animals, reproduction and the ability to provoke the non-specific infection. Other parameters such as toxicity and allergenicity of the preparations and their standardization will be investigated under the absence of such ability. The appropriate schemes and methods of investigations have been developed.
The authors submit an individualized programme of prophylactic and health promotion measures to be instituted on the basis of assessment of the environmental factors impact, health status (age, sex, nationality etc.), pattern of rebuilding in the principal homeostatic systems. Participation of scientists, physicians-practitioners, every individual is essential in the realization of the programme, but there is no alternative to it. A problem of such an importance as health and future of the nation warrants the state institutes of power to be involved to solve it.
An epidemiological study was made on special features of prevalence of disorders of the endocrine system among the rural population over the period 1992-1996 based upon 8 regions of Ukraine. The role has been ascertained of ecological factors in modification of contingent prevalence of endocrine diseases. A hypothesis has been framed that there is the "exposure-->effect" type relationship between abnormal levels of radiation contamination and risk for origination of disorders of the endocrine system and increase in endocrine morbidity.
A genetic monitoring was conducted in a number of ecological regions of Precarpathia on the basis of clinical and epidemiological indices for the frequency of spontaneous abortions, specific weight of multiple birth, dynamics of number born living over the twelve-year period of 1985-1996, with the incidence and nosological spectrum of congenital malformations and hereditary diseases having been characterized. Negative genetic changes were disclosed in those communities under health-hazard conditions. Predominance of spontaneous abortions early in gestation was established together with decline in birth rate, increase in perinatal mortality, congenital malformations, and hereditary diseases in neonates and in children having died in the perinatal period.
The paper presents a clinical material on effects of health-resort factors, hyperbaric oxygenation, and psychotherapeutic correction on the gonadal function in patients having sexual problems. The multimodality approach permitted not only a significant alleviation of pathological symptomatology on the part of the autonomic nervous system, pain syndrome, improving the consistency and function of the prostate, but also had a beneficial effect on the copulative sphere, indices for microscopy of the prostatic secretum, spermatogenesis, and fertility of the ejaculate.
Heavy metals are chief contaminants of the environment, having an adverse effect on the population, especially on children. Results of hygienic and clinical observations suggest to us that compounds of heavy metals might cause changes in functions of metabolism and structure of some organs and systems raising the level of morbidity. It is necessary that a common system be set up of investigations, based on achievements of hygienic science both in this country and abroad; comprehensive investigations designed to study effects of heavy metals on human health be conducted; methodological approaches to the assessment of complex studies be worked out.
Bacterial strains (219) isolated from newborn children were studied for their sensitivity to 17 antibiotics. In the case of the species studied the increase of resistance to cephalothin, cefazolin, cefotaxime, ceftriaxone, gentamicin, tobramycin, chloramphenicol by 5.7 to 43% was found. This evidenced for a necessity to revise the tactics of their further use for treatment and prophylaxis, while the identification of the strains resistant to ofloxacin and ciprofloxacin evidenced for the appearance of new resistance determinants. The high level of resistance to antibiotics and practically identical profile of antibiotics in the strains isolated from newborns and epidemiologically significant environmental objects in the examined hospitals do point to possible colonization of newborns by the hospital strains.
Giant mining industry enterprises and huge iron-and-steel works are located in Krivbas. 169 mll. cu. m. of solid waste, over II.8 mll. cu. m. of waste water, nearly 1.3 mll. tons of dust and gaseous substances are created annually through the production process. Data available from numerous investigations both in this country and abroad refer health characteristics in the community to the environmental contamination. Demographic situation in Krivbas is marked by 22.4% reduction in birth-rate over the last 20 years, 49.2% increase in mortality rates. General mortality showed 2.4-fold increase over the last 5 years. The diseases of respiratory, circulatory and digestive organs are found to prevail as are complications of pregnancy and delivery; on the increase are malignant tumours. 1,600-1,700 diseases per 1,000 children are generally recorded. Planning of measures on protection and promotion of the environment (E) is to be carried out in consecutive order according to the E priority factors in their impact on health in the community. It is necessary that a concept of prenosological diagnosis be used in organization of diagnostic centres for detection of groups at risk for development of a pathology, which undertaking will contribute to early diagnosis as well as timely and well-targeted organization of preventive measures. There is a need for the environmental legislation and mechanisms of its implementation to be improved.
Magnetic fields of industrial frequency with magnetic flux density of 10 mkTl were studied for their effects on the morbidity pattern in the population of the settlement located in the vicinity of a high-voltage electric power line of 750 kV. A trend was noted towards increase in the incidence of nervous and endocrine diseases as well as metabolic disturbances and disorders of the immune system.
Regional features of the course of mental abnormalities are viewed within the framework of a notion about the exogenously organic pathoplastics of psychogenesis inherent in the ecological system of the Lugansk region. Those events are described of transitory subclinical failure of compensation in psyche that present certain distinctive features being region-associated. A proposition is substantiated to the effect that the above clinical features are to be taken into account of when opting for this or that treatment.