The paper analyzes the clinical and laboratory features of Lamblia infection in children living under long-term low-dose chemical load. The scientific search methodology comprised the meticulous examination of the patients randomized by the presence or absence of protozoonosis and the statistical processing and expert analysis of the results. The comprehensive approach could define the main signs of the pathomorphism of lambliosis in the areas with high anthropogenic loads and identify immunological disorders, intoxication, and hepatobiliary dysfunctions. The impact of environmentally induced chemical contamination of the biosphere on the natural history of protozoonosis should be borne in mind when evaluating the biological hazard and risk of environmental biological factors on the population health and when scheduling and implementing hygienic and sanitary-and-epidemiological measures to prevent lambliosis in the high anthropogenic load areas.
The immune system and lymphocyte activity of HADP-dependent dehydrogenases were studied in the patients living in the high incidence areas of Krasnoyarsk. The enhanced activity of cellular immunity was found to show up in the presence of considerable impaired lymphocyte metabolic processes, the change of the rate of which depended on the type of environmental pollution.
Nanoindustry encompasses very different branches of industry today. It should be noted that these are precisely the investigators who deal with researches and developments of nanomaterials will be to the largest measure exposed and hence the likelihood of the potential harm to their health is greatest. To elaborate the special regulations and programs, normative documents and guidelines designed to afford safety and health protection of the employees at work, which should consider the specific characteristics of nanotechnologies. Since 2007, work has proceeded on the safety evaluation of nanoparticles and nanomaterials. Nanotechnology as a key priority in the foreseeable future poses a number of problems facing hygiene science to develop hygienic safety criteria for the production, usage, utilization and storage of various nanomaterials and to elaborate procedures for determination of nanoparticles in different media. Russia will be able to rapidly progress in solving the safety problems in emerging nanoindustry and to minimize human health and environmental risks associated with the manufacture and use of nanoproducts.
The maintenance and development of the centralized household underground water supply system in the closed administrative-territorial entity Seversk, Tomsk Region, when the aquifers are inadequately protected and there is a hydrological association of individual aquifers with polluted surface waters require a hygienic estimation based on the use of a risk methodology, including that considering the regional feature of sanitary situation establishment. No risk realization has been ascertained for damage to critical organs and systems in pediatric and adult populations under the population influence of the chemical substances available in drinking water.
Nanotechnologies find wide application in industry and medicine. The Russian market of nanotechnologies is at the very beginning of development. Rospotrebnadzor has amassed a wealth of experience in the creation of efficacious systems for estimation and sanitary-epidemiological control of the safety of goods and foodstuffs. The assessment of the safety of nanoparticles and nanomaterials has been carried out since 2007. In 2008-2009, a survey was initiated with a view to developing safety criteria for nanoproducts, nanomaterials, and nanotechnologies. In 2010, research institutions of Rospotrebnadzor were engaged in investigations aimed to develop relevant regulatory and procedural documentation. Studies are underway to work out new highly sensitive methods for the detection, identification and qualitative determination of nanomaterials in the environment, food-staffs, and biological media.
The unique climatic and geographical location of the Altai Krai determines the specific radiation dose load for the population, which is composed of the complex of radiological indices, the structure of which is largely dependent on the type of locality and, to a greater extent due to the action of radon, which is currently the main source of internal radiation of the population of upland districts and adjacent territories. There was performed a hygienic assessment of the radiation risk and the expected decline in life expectancy and population health due to radon exposure in the model areas of the Altai Krai. To calculate the additional risk there were used some models for radiation risk extrapolation: a risk constant model, model GSF (Jacobi's model), Lubin model (TSE/AGE/WL) and BEIR VI model for smoking and nonsmoking population, as well as the combined model. The lowest values of the radiation risk and the expected decline in life expectancy are typical for Charyshsko-Ust-Kalmanskaya zone, the maximum--for Kuryinsko--Pospelikhinskaya zone.
With the purpose of the analysis of general trends in the development of risk assessment methodology in Russia the results obtained with the her help, as well as existing methodological problems, there was performed a review of 68 published works concerning the assessment of the health risk for population under the exposure to chemicals in drinking water carried out in 42 cities and regions of the country. There was made the grouping of Russian cities on individual carcinogenic risk level and ranking on the values for the population carcinogenic risk. A list of prioritized carcinogens in tap water has been made. By the values of the risk indices to adverse effects of chemicals tap water there are exposed central nervous system, kidneys, liver, skin and mucous membranes, blood, bone, immune system, hormone homeostasis, blood circulation and digestion organs. There are identified methodological problems leading to an underestimation of the actual risk to public health under exposure of chemicals in drinking water: there are no used regional and age differences in exposure factors, virtually there is no assessed health risk for children population; there is ignored age sensitivity to carcinogens, there is rarely estimated exposure for all the real exposing routes of income and there are no carried out risk calculations at the upper limit (90- 95th percentile) of the exposure.
There is presented the analysis of medical-demographic situation in Russia, and the increase in population mortality is shown both to be associated with the degradation of the geosphere and alongside with other factors determined by the change in the electronic state of the environment. On the base of the interrelationship between the electronic saturation of the environment and an increase in population mortality and morbidity there is established a such risk factor for human health and life, which may currently become one out of significant, videlicet, the electronic deficit. In conditions of its appearance there are proposed options solving this problem by means of elaboration of the scientific rationale for the impact of the electronic deficit on the human organism and the creation of technologies providing environmental--medical safety of the population by virtue of the correction of the electronic state of the human habitat, food and drinking water and the implementation of the system for monitoring electronic abundance of the environment.
The diabetes mellitus is a real threat to population health in all countries. In international practice studying and successful solutions of problems conditioned by this disease are related to development of registries. The Novosibirsk municipal registry of diabetes mellitus is an integral part of the Public registry. The data of municipal registry and analysis of conditions of environment were used to detect characteristics of morbidity of diabetes mellitus in population residing in the territories with different level of anthropogenic pollution by aero-pollutants. The technique of mapping was applied to develop thematic clinical hygienic map. The technique of the thematic clinical hygienic mapping broaden functional possibilities and sphere of application of territorial registry of diabetes mellitus. This technique opens new possibilities and perspectives in development of complex programs of prevention in the territories with anthropogenic pollution.
[The resolution of the Plenum of the Research Council on Human Ecology and Environmental Hygiene of the Russian Federation "Updated issues of human health and the environment and ways of solving them"].
In this paper there was performed an analysis of the application of sanitary norms and rules concerning sanitary protective zones and sanitary classification of enterprises, buildings and other facilities, including requirements for the sufficiency and accuracy of information in the performance of projects in sanitary protection zone (SPZ). There is presented an analysis of regulations that set requirements for implementation of mapping works in drafting the SPZ. The design of the SPZ was shown to be, on the one hand, the element of territorial planning subjects of the Russian Federation, on the other hand, the object of capital construction. The substantiations of requirements for graphic and text content, structure, and composition of data, sources of their obtaining, methods of data convergence are reported. There are revealed inconsistencies in Sanitary Regulations and Norms (SanPins) and in their relationship with the Town Planning and Land Code and other laws, and regulations adopted in their development.
There was investigated the impact of socioeconomic factors on medical and demographic processes in working age population. For the assessment of the impact of living conditions and environmental factors on mortality rate in a population of the Sverdlovsk region factor-typological, correlation and regression analyzes were applied There was shown an availability of statistically significant correlation relationships between mortality of the population of working age and socio-economic characteristics (degree of home improvement, quality of medical care, the level of social tension, the level of the demographic load), as well as between their increments with taking into account the time shifts. The effect of the value of the purchasing power on the mortality rate of the working population has been established The purchasing power was shown to be connected with a mortality rate of working population from external causes more stronger than death from all causes.
Climatic factor is most important condition for the formation of public health. Attention to it has increased recently against the background of global and regional climate change. The aim of the study was to investigate the effect of air temperature on population die off in the Voronezh city in the period of fire-related emergencies. Assessment of cause-and-effect relationships between the air temperature and daily death cases s was performed with the help of the method of time series. Correlation analysis showed a statistically significant positive relationship between air temperature and population die off from all causes and from diseases of the circulatory system with a lag of 0, 1, 2, 3 days; respiratory diseases - with a lag of 3 days. With the gain in air temperature by one degree the number of deaths increases by 3%. The results were used in adopt management decisions on minimization risks and potential negative effects on human health.
Modern data determining drinking water supply crisis in Russia have been considered. The probability of influence of drinking water quality used by population on current negative demographic indices was shown. The necessity of taking into account interests of public health care in the process of formation of water management decisions was grounded. To achieve this goal the application of medical ecological interdisciplinary approach was proposed Its use is mostly effective in construction of goal-directed medical ecological sections for territorial schemes of the rational use and protection of water resources. Stages of the elaboration of these sections, providing the basing of evaluation and prognostic medical and environmental constructions on similar engineering studies of related disciplinary areas (hydrological, hydrogeological, hydrobiological, hydrochemical, environmental, socio-economic, technical and technological) were determined.
One of the main criteria which determine the possibility of the use of a particular type of ice-melter reagents (IMR) is the degree of their safety for the environment and human health, which is reflected in the establishment of safe doses and concentrations. In this regard, the current area of research is to improve the ecological and epidemiological principles of risk assessment of modern types of anti-icing agents. Currently available data concerning monitoring soil studies and the snow held in various cities of Russia, show that there is a process of accumulation of the main components of IMR - sodium and chlorine ions in the areas related to the roadway. The article is designated a problem of existing methodological approaches to the assessment of the phytotoxic impact in the investigation of anti-icing agents in the laboratory. There was executed the comparative characteristics of the results of the preliminary pilot studies on the phytotoxic properties of IMR under using different substrates for germination of seeds - soil and filter paper. The data obtained are characterized by differences in the degree of phytotoxic action of the same species depending upon ice-melter reagents methodical setting circuit laboratory experiment. As a result, there was shown the imperfection of the existing method of rapid analysis in relation to ice-melter materials (IMM).
Negative trends in incidence rates of children and adolescents of the city of Penza are due to the influence of both environmental factors as well as the educational process. Hygienic trouble in the city of Penza determines air pollution emissions of road transport, as evidenced by the high levels of morbidity rate in children and adolescents. The priorities for the correction factors are conditions and the organization of nutrition, physical education. There are identified the most important lifestyle factors for senior pupils that need the solution.
There was executed the ecologic-hygienic assessment of the distribution of respiratory diseases prevalence in bioclimatic zones of the Primorsky Krai. The aim of the study was a systematic assessment of the impact of ecological-hygienic factors of environment on the distribution of respiratory diseases in adolescents and children of the Primorsky region. As an information database there were used indices of the prevalence of diseases of the respiratory system of the ICD-10 class of the official statistical report forms for the period of2000-2013 and the parameters of the environment offactor modules (6 - socio-sanitary, 5 - environmental). The numerical values of modules offactors were determined according to a specially developed scoring scale. The study of the prevalence was carried out with the use of a classical method of data analysis - descriptive statistics, Chi-square criteria. By means of the method of regression analysis from the SPSS package software there was established the relationship of environmental factors and the level of the prevalence of diseases, and were calculated values of the factor loadings influencing on the morbidity rate of children and adolescents. The study revealed that in the structure of morbidity diseases of the respiratory system account of 39% in adolescents, 61% - in children. Constructed predictive models describe the trend of the increasing in the prevalence in adolescents and children. Over the past 15 years, the level of respiratory diseases morbidity rate increased by 46.1%. It is established that the prevalence of respiratory diseases in children and adolescents from various districts of the Primorsky territory depends on the features of the bioclimatic zones and the degree of sanitary-hygienic situation, as well as combinations of parameters that form these zones; the highest cumulative level of the prevalence is observed in the bioclimatic zone of the coast, that is caused by the various degree of the impact of biotropic factors of environment; The prevalence of diseases of respiratory system is mainly affected by bioclimatic factors: residence in an area of high humidity, temperature swings, movements of air masses in combination with air pollution.
The realization of the package of measures directed at the consecutive decrease of the negative effect of hazardous chemical and biological factors on the population and environment to the acceptable risk level stipulates the development of standard legal regulation in the field of ensuring the chemical and biological safety. For this purpose article presents substantiation and conceptual approaches to the creation of legislation in the field of the chemical and biological security of the Russian Federation within the pursued state policy. In determination of conceptual approaches, in the article there are reported: the main idea, the purpose, a subject of legal regulation, the circle of people who will be subjected to the laws, the place offuture laws in the system of current legislation, the provisions of the Constitution of the Russian Federation, the Federal backbone laws of the Russian Federation to realization of which laws are directed, there is given the general characteristic and an assessment of a condition of legal regulation in this field, results of the analysis of the information on the need for correspondence of Russian laws to provision of international treaties, concerning prohibitions of the biological and chemical weapon, safe handling with biological agents and chemicals, and also the development of uniform procedures of ensuring chemical and biological safety. The major aspect in the shaping of the legislation is the global character ofproblems of chemical and biological safety in this connection in article there is indicated the need of rapprochement of rules of law for this area with partners in economic cooperation and integration. Taking into account an orientation of future laws on the decrease in the level of the negative impact of dangerous chemical and biological factors on the population and environment, there are designated medical, social, economic and political consequences of their implementation. There are presented the proposed structure for bills: “About biological safety”, “On Chemical Safety” and “On the National collection of pathogens.