Skip header and navigation

Refine By

4184 records – page 1 of 419.

What characteristics predispose to continence in nursing home residents?: a population-based cross-sectional study.

https://arctichealth.org/en/permalink/ahliterature269158
Source
Neurourol Urodyn. 2015 Apr;34(4):362-7
Publication Type
Article
Date
Apr-2015
Author
Susan Saga
Anne Guttormsen Vinsnes
Siv Mørkved
Christine Norton
Arnfinn Seim
Source
Neurourol Urodyn. 2015 Apr;34(4):362-7
Date
Apr-2015
Language
English
Publication Type
Article
Keywords
Activities of Daily Living
Age Factors
Aged
Aged, 80 and over
Chi-Square Distribution
Comorbidity
Cross-Sectional Studies
Fecal Incontinence - diagnosis - epidemiology
Female
Homes for the Aged
Humans
Length of Stay
Linear Models
Male
Multivariate Analysis
Norway - epidemiology
Nursing Homes
Prevalence
Risk factors
Severity of Illness Index
Surveys and Questionnaires
Urinary Incontinence - diagnosis - epidemiology
Abstract
To compare characteristics of both continent and incontinent residents in Nursing Homes (NHs) and to explore what predicts continence and severity of incontinence.
A population-based cross-sectional study was performed in nursing homes in one Norwegian municipality. Registered nurses filled in a questionnaire on behalf of the patients.
We found that 25.4% of the NH residents were continent, 31.8% had urinary incontinence alone, 2.6% had fecal incontinence alone and 40.2% had double incontinence. Continent residents were characterized by being in short-term care, shorter stay in NH, less cognitive and physical impairment, less Parkinson's disease, stroke, constipation, and less diarrhea and more independence in activities of daily living (ADL). Residents with fecal incontinence alone were characterized by more diarrhea, less cognitive impairment and less dependency in ADL such as feeding and grooming. Residents with urinary incontinence alone were characterized by having some degree of ADL dependency, less diarrhea, and less diabetes. Residents with double incontinence were characterized by being in long-term care, a longer length of stay in NH, cognitive impairment, stroke, constipation, diarrhea, and dependency in ADL. Severity of incontinence was associated with dependency in ADL and cognitive impairment, diarrhea, length of stay in NH and lower age.
About 25% of NH residents were continent. Double incontinence and urinary incontinence only were prevalent conditions in NHs, while FI alone was rarer. With the exception of diarrhea as a cause of FI, it appears that FI alone, UI alone, and DI may have common causes and development.
PubMed ID
24470319 View in PubMed
Less detail

Impact of Statin Adherence on Cardiovascular Morbidity and All-Cause Mortality in the Primary Prevention of Cardiovascular Disease: A Population-Based Cohort Study in Finland.

https://arctichealth.org/en/permalink/ahliterature269208
Source
Value Health. 2015 Sep;18(6):896-905
Publication Type
Article
Date
Sep-2015
Author
Piia K Rannanheimo
Pekka Tiittanen
Juha Hartikainen
Arja Helin-Salmivaara
Risto Huupponen
Jussi Vahtera
Maarit Jaana Korhonen
Source
Value Health. 2015 Sep;18(6):896-905
Date
Sep-2015
Language
English
Publication Type
Article
Keywords
Aged
Cardiovascular Diseases - diagnosis - mortality - prevention & control
Cause of Death
Dyslipidemias - diagnosis - drug therapy - mortality
Female
Finland - epidemiology
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Incidence
Male
Medication Adherence
Middle Aged
Multivariate Analysis
Primary prevention - methods
Propensity Score
Proportional Hazards Models
Registries
Retrospective Studies
Risk assessment
Risk factors
Time Factors
Treatment Outcome
Abstract
To assess the extent to which adherence to statins is associated with the incidence of cardiovascular (CV) events and all-cause mortality in the primary prevention of CV diseases and whether different analytical approaches influence the observed associations.
This population-based cohort study used data from Finnish registers. The cohort included 97,575 new statin users aged 45 to 75 years in 2001 to 2004 with no CV diseases at baseline. Exposure was defined as adherence to statins (proportion of days covered [PDC]). The primary outcome was any CV event or death during a 3-year follow-up. Different analytical approaches, including multivariable-adjusted Cox regression, inverse probability weighting with time-varying adherence, and propensity score calibration, were used.
During the first year of follow-up, 53% displayed good (PDC =80%), 26% had intermediate (PDC 40%-79%), and 21% exhibited poor (PDC
PubMed ID
26409618 View in PubMed
Less detail

Anal human papillomavirus and HIV: A cross-sectional study among men who have sex with men in Moscow, Russia, 2012-2013.

https://arctichealth.org/en/permalink/ahliterature269253
Source
Euro Surveill. 2015;20(15)
Publication Type
Article
Date
2015
Author
A L Wirtz
C E Zelaya
A. Peryshkina
I. McGowan
R D Cranston
C. Latkin
N. Galai
V. Mogilniy
P. Dzhigun
I. Kostetskaya
C. Beyrer
Source
Euro Surveill. 2015;20(15)
Date
2015
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Anal Canal - virology
Anus Diseases - epidemiology - prevention & control - virology
Coinfection - epidemiology - virology
Cross-Sectional Studies
Genotype
HIV Infections - epidemiology - virology
Homosexuality, Male - statistics & numerical data
Humans
Logistic Models
Male
Middle Aged
Moscow - epidemiology
Multivariate Analysis
Papillomaviridae - isolation & purification
Papillomavirus Infections - epidemiology - pathology - prevention & control - virology
Prevalence
Risk factors
Sexual Behavior
Surveys and Questionnaires
Young Adult
Abstract
Anal human papillomavirus (HPV) is prevalent among men who have sex with men (MSM), but has not been studied in the Russian Federation. A cross-sectional survey and HPV genotyping were conducted among HIV seropositive (n=58) and seronegative MSM (n=65)in Moscow. Multivariable logistic regression was performed to identify correlates of infection with oncogenic HPV genotypes 16 and/or 18 (HPV 16/18). Forty per cent (49/124) of all MSM were infected with at least one anal HPV genotype, 31.5% (39/124) had HPV16/18,and 11.5% (14/121) had high-grade squamous intraepithelial lesions (HSIL). HPV 16/18 was more prevalent in HIV seropositive than seronegative men (24/58,41.4% vs 15/65, 23.1%; p=0.03). HIV infection was independently associated with HPV 16/18 (adjusted odds ratio (AOR): 5.08; 95% confidence intervals (CI):1.49-17.34, p=0.01), as was having 2-4 steady male sex partners in the last year (vs = 1 partner; AOR: 6.99;95%CI: 1.94–25.24, p
Notes
Erratum In: Euro Surveill. 2015;20(17). pii: 2111025955778
PubMed ID
25953132 View in PubMed
Less detail

Nonesterified fatty acids and cardiovascular mortality in elderly men with CKD.

https://arctichealth.org/en/permalink/ahliterature269312
Source
Clin J Am Soc Nephrol. 2015 Apr 7;10(4):584-91
Publication Type
Article
Date
Apr-7-2015
Author
Zibo Xiong
Hong Xu
Xiaoyan Huang
Johan Ärnlöv
Abdul Rashid Qureshi
Tommy Cederholm
Per Sjögren
Bengt Lindholm
Ulf Risérus
Juan Jesús Carrero
Source
Clin J Am Soc Nephrol. 2015 Apr 7;10(4):584-91
Date
Apr-7-2015
Language
English
Publication Type
Article
Keywords
Age Factors
Aged
Albuminuria - diagnosis - mortality - physiopathology
Biomarkers - blood
Cause of Death
Comorbidity
Diabetes Mellitus - mortality
Fatty Acids, Nonesterified - blood
Glomerular Filtration Rate
Humans
Kaplan-Meier Estimate
Kidney - physiopathology
Linear Models
Longitudinal Studies
Male
Multivariate Analysis
Myocardial Infarction - blood - diagnosis - mortality
Prognosis
Proportional Hazards Models
Prospective Studies
Renal Insufficiency, Chronic - blood - diagnosis - mortality - physiopathology
Risk factors
Sex Factors
Sweden - epidemiology
Time Factors
Triglycerides - blood
Up-Regulation
Abstract
Although nonesterified fatty acids (NEFAs) are essential as energy substrate for the myocardium, an excess of circulating NEFAs can be harmful. This study aimed to assess plausible relationships between serum NEFA and mortality due to cardiovascular disease (CVD) in individuals with CKD.
This was a prospective cohort study from the third examination cycle of the Uppsala Longitudinal Study of Adult Men, a population-based survey of 1221 elderly men aged 70-71 years residing in Uppsala, Sweden. Data collection took place during 1991-1995. All participants had measures of kidney function; this study investigated 623 (51.7%) of these patients with manifest CKD (defined as either eGFR
Notes
Cites: Curr Opin Endocrinol Diabetes Obes. 2011 Apr;18(2):139-4321297467
Cites: Nephrol Dial Transplant. 2011 Jan;26(1):270-620621930
Cites: J Am Coll Cardiol. 2000 Oct;36(4):1386-811028499
Cites: Am J Epidemiol. 2001 Feb 1;153(3):292-811157417
Cites: Circulation. 2001 Aug 14;104(7):756-6111502698
Cites: Diabetologia. 2001 Dec;44(12):2134-911793014
Cites: Atherosclerosis. 2002 Feb;160(2):377-8411849661
Cites: Am J Kidney Dis. 2002 Feb;39(2 Suppl 1):S1-26611904577
Cites: Scand J Clin Lab Invest. 2004;64(1):25-3015025426
Cites: Proc Nutr Soc. 2004 May;63(2):369-7415294057
Cites: JAMA. 1966 Mar 28;195(13):1095-85952074
Cites: Am Heart J. 1970 Nov;80(5):671-45474102
Cites: Am J Physiol. 1979 Sep;237(3):E214-23382871
Cites: Cardiovasc Drugs Ther. 1991 Aug;5(4):753-611888696
Cites: Clin Chim Acta. 1991 Dec 31;204(1-3):251-611819468
Cites: Diabetologia. 1994 Oct;37(10):1044-507851683
Cites: Indian Heart J. 1995 Sep-Oct;47(5):471-68714500
Cites: Diabetes. 1997 Jan;46(1):3-108971073
Cites: Am J Clin Nutr. 1997 Apr;65(4 Suppl):1220S-1228S; discussion 1229S-1231S9094926
Cites: Int J Epidemiol. 1997 Dec;26(6):1323-339447413
Cites: Arterioscler Thromb Vasc Biol. 1998 Feb;18(2):258-649484991
Cites: Ann N Y Acad Sci. 2004 Nov;1033:79-9115591005
Cites: Am J Physiol Renal Physiol. 2006 Feb;290(2):F262-7216403839
Cites: Pediatr Nephrol. 2006 Mar;21(3):308-1716374652
Cites: J Clin Endocrinol Metab. 2006 Jul;91(7):2542-716595593
Cites: QJM. 2006 Oct;99(10):701-916935924
Cites: Curr Drug Targets. 2012 Feb;13(2):285-9322204325
Cites: Circ Arrhythm Electrophysiol. 2012 Apr;5(2):273-822281952
Cites: Hemodial Int. 2012 Jul;16(3):428-3422360675
Cites: Ann Intern Med. 2013 Jun 4;158(11):825-3023732715
Cites: BMC Med Res Methodol. 2013;13:14824308700
Cites: Am J Cardiol. 2014 Jan 15;113(2):279-8424176067
Cites: Antioxid Redox Signal. 2014 Mar 20;20(9):1382-9524063548
Cites: Heart Rhythm. 2014 Apr;11(4):691-624418168
Cites: Clin J Am Soc Nephrol. 2014 Apr;9(4):690-724436478
Cites: Clin Exp Nephrol. 2014 Apr;18(2):265-823974528
Cites: Kidney Int. 2014 Aug;86(2):383-9124476695
Cites: Eur Heart J. 2007 Nov;28(22):2763-917766282
Cites: Eur Heart J. 2007 Nov;28(22):2699-70017933757
Cites: Clin Chem Lab Med. 2008;46(4):429-3418605928
Cites: J Am Coll Cardiol. 2009 Oct 27;54(18):1637-4619850204
Cites: Nephrol Dial Transplant. 2011 Sep;26(9):2820-721335440
PubMed ID
25637632 View in PubMed
Less detail

Heroin Use and HIV Disease Progression: Results from a Pilot Study of a Russian Cohort.

https://arctichealth.org/en/permalink/ahliterature269331
Source
AIDS Behav. 2015 Jun;19(6):1089-97
Publication Type
Article
Date
Jun-2015
Author
E Jennifer Edelman
Debbie M Cheng
Evgeny M Krupitsky
Carly Bridden
Emily Quinn
Alexander Y Walley
Dmitry A Lioznov
Elena Blokhina
Edwin Zvartau
Jeffrey H Samet
Source
AIDS Behav. 2015 Jun;19(6):1089-97
Date
Jun-2015
Language
English
Publication Type
Article
Keywords
Adult
Anti-HIV Agents - therapeutic use
CD4 Lymphocyte Count - statistics & numerical data
Disease Progression
Female
HIV Infections - complications - drug therapy - epidemiology - virology
Heroin Dependence - complications - epidemiology
Humans
Longitudinal Studies
Male
Multivariate Analysis
Pilot Projects
Prevalence
Regression Analysis
Risk factors
Russia - epidemiology
Socioeconomic Factors
Viral Load - drug effects
Abstract
Opioids have immunosuppressive properties, yet their impact on HIV disease progression remains unclear. Using longitudinal data from HIV-infected antiretroviral therapy-naïve Russian individuals (n = 77), we conducted a pilot study to estimate the effect of heroin use on HIV disease progression. Heroin use was categorized based on past 30 days self-reported use at baseline, 6 and 12 months as none, intermittent or persistent. We estimated the effect of heroin use on HIV disease progression, measured as change in CD4 count from baseline to 12 months, using multivariable linear regression. Those with intermittent (n = 21) and no heroin use (n = 39) experienced mean decreases in CD4 count from baseline to 12 months (-103 and -10 cells/mm(3), respectively; adjusted mean difference (AMD) -93; 95 % CI -245, 58). Those with persistent use (n = 17) showed a mean increase of 53 cells/mm(3) (AMD 63; 95 % CI -95, 220). Future studies exploring the effects of heroin withdrawal on HIV disease progression are warranted.
Notes
Cites: Curr Opin Support Palliat Care. 2008 Mar;2(1):14-818685388
Cites: Addiction. 2015 Jan;110(1):80-9025170994
Cites: J Acquir Immune Defic Syndr. 2009 Mar 1;50(3):241-919194320
Cites: J Acquir Immune Defic Syndr. 2009 Jan 1;50(1):93-919295339
Cites: Biochim Biophys Acta. 2009 Aug;1793(8):1366-7119477204
Cites: Ann Oncol. 2010 Mar;21(3):615-2620176694
Cites: AIDS Res Hum Retroviruses. 2010 May;26(5):511-820455765
Cites: J Subst Abuse Treat. 2011 Jun;40(4):386-9621353444
Cites: PLoS One. 2011;6(4):e1846221541016
Cites: J Neuroimmune Pharmacol. 2011 Dec;6(4):442-6521789507
Cites: J Neuroimmune Pharmacol. 2011 Dec;6(4):516-2721830069
Cites: Drug Alcohol Depend. 2012 Jul 1;124(1-2):108-1222245312
Cites: Curr Pharm Des. 2012;18(37):6034-4222747543
Cites: Int J Drug Policy. 2013 Jul;24(4):265-7423726898
Cites: Drug Alcohol Depend. 2013 Sep 1;132(1-2):74-8023410616
Cites: Addiction. 2013 Oct;108(10):1779-8723773361
Cites: Drug Alcohol Depend. 2014 Jan 1;134:85-9124120857
Cites: J Neuroimmunol. 1998 Mar 15;83(1-2):77-879610676
Cites: J Pharmacol Exp Ther. 1998 Aug;286(2):883-99694946
Cites: Antivir Ther. 2005;10(1):53-6115751763
Cites: Front Biosci. 2005;10:1666-7715769657
Cites: Addiction. 2005 Jul;100(7):990-100215955015
Cites: Clin Infect Dis. 2005 Oct 1;41(7):1027-3416142670
Cites: Eur Addict Res. 2006;12(1):12-916352898
Cites: Am J Epidemiol. 2006 Mar 1;163(5):412-2016394200
Cites: AIDS. 1999 Dec 24;13(18):2547-5410630524
Cites: J Acquir Immune Defic Syndr. 1999 Dec 1;22(4):369-7810634199
Cites: Drug Alcohol Depend. 2001 Apr 1;62(2):111-2311245967
Cites: AIDS. 2001 Jun 15;15(9):1115-2311416713
Cites: J Acquir Immune Defic Syndr. 2001 Jul 1;27(3):251-911464144
Cites: Lancet. 2002 Jul 13;360(9327):119-2912126821
Cites: AIDS. 2003 Feb 14;17(3):353-912556689
Cites: J Acquir Immune Defic Syndr. 2003 Apr 15;32(5):522-612679704
Cites: Pediatr Res. 2003 Aug;54(2):282-812736382
Cites: J Acquir Immune Defic Syndr. 2004 Jan 1;35(1):46-5114707791
Cites: HIV Med. 2004 Jan;5(1):30-314731167
Cites: J Neuroimmunol. 2004 Feb;147(1-2):28-3214741423
Cites: J Virol. 2004 Oct;78(20):11425-815452267
Cites: J Acquir Immune Defic Syndr. 2004 Nov 1;37(3):1423-3015483472
Cites: AIDS. 1990 Sep;4(9):869-732174676
Cites: Med Care. 1996 Mar;34(3):220-338628042
Cites: AIDS. 2008 Jul 11;22(11):1355-6318580615
Cites: AIDS. 2008 Jan 30;22(3):357-6518195562
Cites: J Neuroimmune Pharmacol. 2006 Sep;1(3):280-9518040805
Cites: J Neuroimmune Pharmacol. 2006 Sep;1(3):250-918040802
Cites: J Neuroimmune Pharmacol. 2006 Sep;1(3):237-4918040801
Cites: J Acquir Immune Defic Syndr. 2007 Oct 1;46(2):194-917667330
Cites: Panminerva Med. 2007 Jun;49(2):67-7717625483
Cites: AIDS. 1997 Aug;11(10):1255-629256944
Cites: AIDS. 2006 Nov 14;20(17):2207-1517086061
Cites: Lancet. 2008 Nov 15;372(9651):1733-4518817968
PubMed ID
25413642 View in PubMed
Less detail

Altered frequency distribution in the electroencephalogram is correlated to the analgesic effect of remifentanil.

https://arctichealth.org/en/permalink/ahliterature269341
Source
Basic Clin Pharmacol Toxicol. 2015 May;116(5):414-22
Publication Type
Article
Date
May-2015
Author
Carina Graversen
Lasse P Malver
Geana P Kurita
Camilla Staahl
Lona L Christrup
Per Sjøgren
Asbjørn M Drewes
Source
Basic Clin Pharmacol Toxicol. 2015 May;116(5):414-22
Date
May-2015
Language
English
Publication Type
Article
Keywords
Adult
Analgesics, Opioid - administration & dosage
Brain - drug effects - physiopathology
Brain Waves - drug effects
Cross-Over Studies
Denmark
Double-Blind Method
Electroencephalography
Healthy Volunteers
Hot Temperature - adverse effects
Humans
Infusions, Parenteral
Male
Multivariate Analysis
Pain - etiology - physiopathology - prevention & control
Pain Measurement
Pain Perception - drug effects
Pain Threshold - drug effects
Piperidines - administration & dosage
Predictive value of tests
Pressure - adverse effects
Signal Processing, Computer-Assisted
Time Factors
Young Adult
Abstract
Opioids alter resting state brain oscillations by multiple and complex factors, which are still to be elucidated. To increase our knowledge, multi-channel electroencephalography (EEG) was subjected to multivariate pattern analysis (MVPA), to identify the most descriptive frequency bands and scalp locations altered by remifentanil in healthy volunteers. Sixty-two channels of resting EEG followed by independent measures of pain scores to heat and bone pain were recorded in 21 healthy males before and during remifentanil infusion in a placebo-controlled, double-blind crossover study. EEG frequency distributions were extracted by a continuous wavelet transform and normalized into delta, theta, alpha, beta and gamma bands. Alterations relative to pre-treatment responses were calculated for all channels and used as input to the MVPA. Compared to placebo, remifentanil increased the delta band and decreased the theta and alpha band oscillations as a mean over all channels (all p = 0.007). The most discriminative channels in these frequency bands were F1 in delta (83.33%, p = 0.0023) and theta bands (95.24%, p
PubMed ID
25250670 View in PubMed
Less detail

Replacing sugary drinks with milk is inversely associated with weight gain among young obesity-predisposed children.

https://arctichealth.org/en/permalink/ahliterature269525
Source
Br J Nutr. 2015 Nov 14;114(9):1448-55
Publication Type
Article
Date
Nov-14-2015
Author
Miaobing Zheng
Anna Rangan
Margaret Allman-Farinelli
Jeanett Friis Rohde
Nanna Julie Olsen
Berit Lilienthal Heitmann
Source
Br J Nutr. 2015 Nov 14;114(9):1448-55
Date
Nov-14-2015
Language
English
Publication Type
Article
Keywords
Animals
Beverages - analysis
Body mass index
Child
Child Nutritional Physiological Phenomena
Child, Preschool
Denmark
Energy intake
Female
Humans
Linear Models
Male
Milk
Motor Activity
Multivariate Analysis
Nutritive Sweeteners - adverse effects - analysis
Pediatric Obesity - prevention & control
Socioeconomic Factors
Weight Gain
Abstract
The aim of the present study was to examine the associations of sugary drink consumption and its substitution with alternative beverages with body weight gain among young children predisposed to future weight gain. Secondary analysis of the Healthy Start Study, a 1·5-year randomised controlled trial designed to prevent overweight among Danish children aged 2-6 years (n 366), was carried out. Multivariate linear regression models were used to investigate the associations of beverage consumption with change in body weight (?weight) or BMI(?BMI) z-score. Substitution models were used to extrapolate the influence of replacing sugary drinks with alternative beverages (water, milk and diet drinks) on ?weight or ?BMI z-score. Sugary drink intake at baseline and substitution of sugary drinks with milk were associated with both ?weight and ?BMI z-score. Every 100 g/d increase in sugary drink intake was associated with 0·10 kg and 0·06 unit increases in body weight (P=0·048) and BMI z-score (P=0·04), respectively. Substitution of 100 g/d sugary drinks with 100 g/d milk was inversely associated with ?weight (ß=-0·16 kg; P=0·045) and ?BMI z-score (ß=-0·07 units; P=0·04). The results of this study suggest that sugary drink consumption was associated with body weight gain among young children with high predisposition for future overweight. In line with the current recommendations, sugary drinks, whether high in added or natural sugar, should be discouraged to help prevent childhood obesity. Milk may be a good alternative to sugary drinks with regard to weight management among young obesity-predisposed children.
PubMed ID
26328600 View in PubMed
Less detail

The relationship between caregiver burden, caregivers' perceived health and their sense of coherence in caring for elders with dementia.

https://arctichealth.org/en/permalink/ahliterature87066
Source
J Clin Nurs. 2008 Mar;17(6):790-9
Publication Type
Article
Date
Mar-2008
Author
Andrén Signe
Elmståhl Sölve
Author Affiliation
Department of Health Sciences, Division of Geriatric Medicine, Lund University, Malmö University Hospital, Malmö, Sweden. signe.andren@med.lu.se
Source
J Clin Nurs. 2008 Mar;17(6):790-9
Date
Mar-2008
Language
English
Publication Type
Article
Keywords
Adaptation, Psychological
Adult
Aged
Aged, 80 and over
Caregivers - psychology
Cluster analysis
Cost of Illness
Cross-Sectional Studies
Dementia - nursing
Family Nursing
Female
Health status
Humans
Male
Middle Aged
Multivariate Analysis
Regression Analysis
Sweden
Abstract
AIM: The aim of this study is to examine associations between caregiver burden, perceived health and sense of coherence in family caregivers to persons with dementia living at home. BACKGROUND: Most of the studies on family caregivers have focused on burden and morbidity. However, the caregiver's sense of coherence and perceived health have not been studied earlier in relation to caregiver burden. DESIGN: A cross-sectional investigation design was used. METHODS: Older persons, 2238 subjects, with any form of social services, were invited to an assessment of cognitive capacity. Those who had cognitive decline (255) were invited for a medical examination and 130 persons were diagnosed as having dementia. The family caregivers to persons with dementia answered a questionnaire including a caregiver burden scale, the Nottingham health profile scale, sense of coherence scale and the Euroqol instrument. RESULTS: The family caregivers experienced moderate burden, and strong associations were noted between burden, especially isolation, disappointment and emotional involvement with perceived health and sense of coherence, adjusted for age and relationship. Caregivers with lower burden reported significantly better perceived health and higher mean score of sense of coherence than caregivers with higher burden. CONCLUSIONS: Assessment of status of family caregivers of persons with dementia living at home seems to be gaining considerable importance. The caregiver burden scale and the sense of coherence scale seem to be highly useful for identifying carers at risk of stress, pattern of burden and coping strategies. RELEVANCE TO CLINICAL PRACTICE: Nurses can help family caregivers to identify their negative experiences about caregiving and can help them reflect upon their coping strategies to find balance in their situation. Risk groups of caregivers may be identified, especially those with low perceived health and sense of coherence, for early interventions to reduce burden.
PubMed ID
18279282 View in PubMed
Less detail

The effects of on-pump and off-pump coronary artery bypass grafting on intraoperative graft flow in arterial and venous conduits defined by a flow/pressure ratio.

https://arctichealth.org/en/permalink/ahliterature87226
Source
J Thorac Cardiovasc Surg. 2008 Mar;135(3):533-9
Publication Type
Article
Date
Mar-2008
Author
Balacumaraswami Lognathen
Abu-Omar Yasir
Selvanayagam Joseph
Pigott David
Taggart David P
Author Affiliation
Department of Cardiothoracic Surgery, John Radcliffe Hospital, Headington, Oxford, United Kingdom.
Source
J Thorac Cardiovasc Surg. 2008 Mar;135(3):533-9
Date
Mar-2008
Language
English
Publication Type
Article
Keywords
Aged
Anastomosis, Surgical
Coronary Angiography
Coronary Artery Bypass - methods - mortality
Coronary Artery Bypass, Off-Pump - methods - mortality
Coronary Circulation - physiology
Coronary Disease - mortality - radiography - surgery
Female
Fluorescence
Graft Rejection
Graft Survival
Great Britain
Heart Catheterization
Humans
Male
Mammary Arteries - physiology - transplantation
Middle Aged
Monitoring, Intraoperative - methods
Multivariate Analysis
Pressure
Probability
Prognosis
Prospective Studies
Pulsatile Flow
Radial Artery - physiology - transplantation
Statistics, nonparametric
Survival Rate
Treatment Outcome
Vascular Patency - physiology
Abstract
OBJECTIVE: Despite profound differences in the neurohumoral milieu in patients undergoing on-pump and off-pump coronary artery bypass grafting, it is uncertain how this affects graft blood flow. METHODS: We prospectively recorded intraoperative transit-time flow measurements (MediStim BF 2004; MediStim AS, Oslo, Norway) in all internal thoracic artery, radial artery, and long saphenous vein conduits in patients undergoing off-pump and on-pump bypass grafting by a single surgeon. We calculated a flow/pressure ratio as a ratio of mean graft flow to mean arterial pressure for all the conduits just before chest closure. RESULTS: Transit-time flow measurements were recorded in 266 grafts (203 off-pump; 63 on-pump) in 100 patients (80 off-pump; 20 on-pump). Overall, mean graft flow (milliliters per minute) was higher for all grafts in the on-pump group despite a significantly lower mean arterial pressure compared with the off-pump group (P
PubMed ID
18329465 View in PubMed
Less detail

Smoking is negatively associated with the presence of thyroglobulin autoantibody and to a lesser degree with thyroid peroxidase autoantibody in serum: a population study.

https://arctichealth.org/en/permalink/ahliterature87235
Source
Eur J Endocrinol. 2008 Mar;158(3):367-73
Publication Type
Article
Date
Mar-2008
Author
Pedersen Inge Bülow
Laurberg Peter
Knudsen Nils
Jørgensen Torben
Perrild Hans
Ovesen Lars
Rasmussen Lone Banke
Author Affiliation
Department of Endocrinology and Medicine, Aalborg Hospital, Aarhus University Hospital, DK-9000 Aalborg, Denmark.
Source
Eur J Endocrinol. 2008 Mar;158(3):367-73
Date
Mar-2008
Language
English
Publication Type
Article
Keywords
Adolescent
Adult
Aged
Autoantibodies - blood
Female
Humans
Iodide Peroxidase - immunology
Life Style
Logistic Models
Male
Middle Aged
Multivariate Analysis
Risk factors
Seroepidemiologic Studies
Smoking - epidemiology
Thyroiditis, Autoimmune - epidemiology - immunology
Abstract
BACKGROUND: Autoimmune thyroid diseases are common and the prevalence of circulating thyroid antibodies (thyroid peroxidase antibody, TPO-Ab and thyroglobulin antibody, Tg-Ab) is high in the population. The knowledge of a possible association between lifestyle factors and circulating thyroid antibodies is limited. AIM: To evaluate the correlation between smoking habits and the presence of circulating TPO-Ab and Tg-Ab. MATERIAL AND METHODS: In a cross-sectional comparative population study performed in two areas of Denmark with moderate and mild iodine deficiency, 4649 randomly selected subjects from the population in some predefined age groups between 18 and 65 years were examined. Blood tests were analysed for TPO-Ab and Tg-Ab using assays based on the RIA technique. The participants answered questionnaires, were clinically examined and blood and urine samples collected. RESULTS: Data were analysed in multivariate logistic regression models. There was a negative association between smoking and the presence of thyroid autoantibodies in serum. This association was observed for the presence of TPO-Ab and/or Tg-Ab, TPO-Ab (without respect to Tg-Ab status), Tg-Ab (without respect to TPO-Ab status) and both antibodies together. The association between smoking and thyroid autoantibodies was stronger for Tg-Ab than for TPO-Ab. There was no association between smoking and TPO-Ab measured alone or between smoking and TPO-Ab when Tg-Ab was included in the model as an explanatory variable. CONCLUSION: Smoking was negatively associated with the presence of thyroid autoantibodies with the strongest association between smoking and Tg-Ab. The study design precludes any conclusions as to the cause of the negative association between smoking thyroid autoantibodies.
PubMed ID
18299471 View in PubMed
Less detail

4184 records – page 1 of 419.