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Adolescent psychosis risk symptoms predicting persistent psychiatric service use: A 7-year follow-up study.

https://arctichealth.org/en/permalink/ahliterature298906
Source
Eur Psychiatry. 2019 01; 55:102-108
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
01-2019
Author
Maija Lindgren
Minna Jonninen
Markus Jokela
Sebastian Therman
Author Affiliation
Mental Health Unit, National Institute for Health and Welfare, Helsinki, Finland. Electronic address: maija.lindgren@thl.fi.
Source
Eur Psychiatry. 2019 01; 55:102-108
Date
01-2019
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Adolescent
Female
Finland - epidemiology
Follow-Up Studies
Humans
Male
Mental Disorders - epidemiology - therapy
Mental Health Services - statistics & numerical data
Patient Acceptance of Health Care - statistics & numerical data
Prodromal Symptoms
Prognosis
Prospective Studies
Psychiatric Status Rating Scales
Psychopathology
Psychotic Disorders - diagnosis - epidemiology - psychology
Risk Assessment - methods
Risk factors
Utilization Review - statistics & numerical data
Abstract
We investigated whether psychosis risk symptoms predicted psychiatric service use using seven-year register follow-up data.
Our sample included 715 adolescents aged 15-18, referred to psychiatric care for the first time. Psychosis risk symptoms were assessed with the Prodromal Questionnaire (PQ) at the beginning of the treatment. We assessed the power of the overall PQ as well as its positive, negative, general, and disorganized psychosis risk symptom factors in predicting prolonged service use. Baseline psychiatric diagnoses (grouped into 7 categories) were controlled for. Based on both inpatient and outpatient psychiatric treatment after baseline, adolescents were divided into three groups of brief, intermittent, and persistent service use.
Stronger symptoms on any PQ factor as well as the presence of a mood disorder predicted prolonged service use. All of the PQ factors remained significant predictors when adjusted for baseline mood disorder and multimorbidity.
In a prospective follow-up of a large sample using comprehensive mental health records, our findings indicate that assessing psychosis risk symptoms in clinical adolescent settings at the beginning of treatment could predict long-term need for care beyond diagnostic information. Our findings replicate the previous findings that positive psychosis risk symptoms are unspecific markers of severity of psychopathology. Also psychosis risk symptoms of the negative, disorganization, and general clusters are approximately as strongly associated with prolonged psychiatric service use in the upcoming years.
PubMed ID
30447416 View in PubMed
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A comparison of the cumulative incidence and early risk factors for psychotic disorder in young adults in the Northern Finland Birth Cohorts 1966 and 1986.

https://arctichealth.org/en/permalink/ahliterature295538
Source
Epidemiol Psychiatr Sci. 2017 06; 26(3):314-324
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
06-2017
Author
S Filatova
R Marttila
H Koivumaa-Honkanen
T Nordström
J Veijola
P Mäki
G M Khandaker
M Isohanni
E Jääskeläinen
K Moilanen
J Miettunen
Author Affiliation
Center for Life Course Health Research,University of Oulu,Oulu,Finland.
Source
Epidemiol Psychiatr Sci. 2017 06; 26(3):314-324
Date
06-2017
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Adult
Child of Impaired Parents - psychology - statistics & numerical data
Cohort Studies
Female
Finland - epidemiology
Humans
Incidence
Male
Mothers - psychology - statistics & numerical data
Pregnancy
Prospective Studies
Psychotic Disorders - diagnosis - epidemiology - psychology
Registries
Schizophrenia - diagnosis - epidemiology
Schizophrenic Psychology
Young Adult
Abstract
Few studies have compared time trends for the incidence of psychosis. To date, the results have been inconsistent, showing a decline, an increase or no significant change. As far as we know, no studies explored changes in prevalence of early risk factors. The aim of this study was to investigate differences in early risk factors and cumulative incidences of psychosis by type of psychosis in two comparable birth cohorts.
The Northern Finland Birth cohorts (NFBCs) 1966 (N = 12 058) and 1986 (N = 9432) are prospective general population-based cohorts with the children followed since mother's mid-pregnancy. The data for psychoses, i.e. schizophrenia (narrow, spectrum), bipolar disorder with psychotic features, major depressive episode with psychotic features, brief psychosis and other psychoses (ICD 8-10) were collected from nationwide registers including both inpatients and outpatients. The data on early risk factors including sex and place of birth of the offspring, parental age and psychosis, maternal education at birth were prospectively collected from the population registers. The follow-up reached until the age of 27 years.
An increase in the cumulative incidence of all psychoses was seen (1.01% in NFBC 1966 v. 1.90% in NFBC 1986; p
PubMed ID
27018550 View in PubMed
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Determinants of duration of untreated psychosis among first-episode psychosis patients in Denmark: A nationwide register-based study.

https://arctichealth.org/en/permalink/ahliterature295757
Source
Schizophr Res. 2018 02; 192:154-158
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
02-2018
Author
Lene Halling Hastrup
Ulrik Helt Haahr
Jens Einar Jansen
Erik Simonsen
Author Affiliation
Psychiatric Research Unit, Region Zealand Psychiatry, Denmark. Electronic address: lhhs@regionsjaelland.dk.
Source
Schizophr Res. 2018 02; 192:154-158
Date
02-2018
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Adolescent
Adult
Age of Onset
Awareness
Demography
Denmark - epidemiology
Early Intervention (Education)
Female
Humans
Male
Psychiatric Status Rating Scales
Psychotic Disorders - diagnosis - epidemiology - psychology
Registries
Young Adult
Abstract
Information on determinants of duration of untreated psychosis (DUP) is still needed to inform campaigns targeting people with first episode psychosis (FEP). This nation-wide study analysed the association between demographic factors (age, sex, ethnicity, marital status, and geographic area), premorbid and illness-related factors (global functional level, substance misuse, and contact to police), healthcare factors (referral source and first FEP contact) and DUP.
The study population of 1266 patients aged 15-25years diagnosed with FEP (ICD10 F20.0-F20.99) was drawn from the Danish National Indicator Project during 2009-2011. The study population was combined with data from national administrative registers. A multinomial regression model was estimated to analyse the impact of demographic, premorbid and illness-related, and healthcare factors on DUP.
One third of the population had a DUP below 6months. DUP longer than 12months was associated with older age at onset, being female, having cannabis misuse, and living in peripheral municipalities. Being charged by the criminal authorities during one year before FEP was associated with a DUP over 6months.
DUP is related to a number of demographic, premorbid and healthcare factors. These findings suggest that future information campaigns should focus on increasing the awareness of early signs of psychosis not only among mental health professionals but also other professionals in contact with adolescents such as the police. It may also be useful to consider how to target information campaigns towards persons living in peripheral areas.
PubMed ID
28578812 View in PubMed
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Continuity between interview-rated personality disorders and self-reported DSM-5 traits in a Danish psychiatric sample.

https://arctichealth.org/en/permalink/ahliterature291088
Source
Personal Disord. 2017 Jul; 8(3):261-267
Publication Type
Journal Article
Date
Jul-2017
Author
Bo Bach
Jaime Anderson
Erik Simonsen
Author Affiliation
Research Unit, Region Zealand.
Source
Personal Disord. 2017 Jul; 8(3):261-267
Date
Jul-2017
Language
English
Publication Type
Journal Article
Keywords
Adult
Denmark
Female
Humans
Interview, Psychological - standards
Male
Personality Disorders - diagnosis - physiopathology
Personality Inventory - standards
Psychiatric Status Rating Scales - standards
Young Adult
Abstract
The Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) Section III offers an alternative model for the diagnosis of personality disorders (PDs), including 25 pathological personality trait facets organized into 5 trait domains. To maintain continuity with the categorical PD diagnoses found in DSM-5 Section II, specified sets of facets are configured into familiar PD types. The current study aimed to evaluate the continuity across the Section II and III models of PDs. A sample of 142 psychiatric outpatients were administered the Personality Inventory for DSM-5 and rated with the Structured Clinical Interview for the DSM-IV Axis II disorders. We investigated whether the DSM-5 Section III facet-profiles would be associated with their respective Section II counterparts, as well as determining whether additional facets could augment the prediction of the Section II disorders. Results showed that, overall, the interview-rated DSM-5 Section II disorders were most strongly associated with expected self-reported Section III traits. Results also supported the addition of facets not included in the proposed Section III PD criteria. These findings partly underscore the continuity between the Section II and III models of PDs and suggest how it may be enhanced; however, additional research is needed to further evaluate where continuity exists, where it does not exist, and how the traits system could be improved. (PsycINFO Database Record
PubMed ID
26784892 View in PubMed
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Stability of personality traits over a five-year period in Swedish patients with schizophrenia spectrum disorder and non-psychotic individuals: a study using the Swedish universities scales of personality.

https://arctichealth.org/en/permalink/ahliterature293445
Source
BMC Psychiatry. 2018 02 27; 18(1):54
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Date
02-27-2018
Author
Tomas Fagerberg
Erik Söderman
J Petter Gustavsson
Ingrid Agartz
Erik G Jönsson
Author Affiliation
Human Brain Informatics (HUBIN), Department of Clinical Neuroscience, Centre for Psychiatric Research, Psychiatry Section, Karolinska Institutet and Hospital, Stockholm, Sweden. Tomas.Fagerberg@ki.se.
Source
BMC Psychiatry. 2018 02 27; 18(1):54
Date
02-27-2018
Language
English
Publication Type
Journal Article
Research Support, Non-U.S. Gov't
Keywords
Adult
Case-Control Studies
Female
Follow-Up Studies
Humans
Male
Middle Aged
Personality
Personality Disorders - diagnosis - epidemiology - psychology
Personality Inventory - standards
Schizophrenia - diagnosis - epidemiology
Schizophrenic Psychology
Sweden - epidemiology
Time Factors
Universities
Abstract
Personality is considered as an important aspect in persons with psychotic disorders. Several studies have investigated personality in schizophrenia. However, no study has investigated stability of personality traits exceeding three years in patients with schizophrenia. This study aims to investigate the stability of personality traits over a five-year period among patients with schizophrenia and non-psychotic individuals and to evaluate case-control differences.
Patients with psychotic disorders (n?=?36) and non-psychotic individuals (n?=?76) completed Swedish universities Scales of Personality (SSP) at two occasions five years apart. SSP scores were analysed for effect of time and case-control differences by multiple analysis of covariance (MANCOVA) and within-subjects correlation.
MANCOVA within-subjects analysis did not show any effect of time. Thus, SSP mean scale scores did not significantly vary during the five-year interval. Within subject correlations (Spearman) ranged 0.30-0.68 and 0.54-0.75 for the different SSP scales in patients and controls, respectively. Patients scored higher than controls in SSP scales Somatic Trait Anxiety, Psychic Trait Anxiety, Stress Susceptibility, Lack of Assertiveness, Detachment, Embitterment, and Mistrust.
The stability of the SSP personality trait was reasonably high among patients with psychotic disorder, although lower than among non-psychotic individuals, which is in accordance with previous research.
PubMed ID
29486736 View in PubMed
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