The aim of our research was to investigate the level of 25-OH vitamin D in blood plasma of indigenous inhabitants of Russia European North. The study showed that there was wide spreading of vitamin D deficiency among northerners especially in teenager. The significant reduction of 25-OH vitamin D3 was revealed in the inhabitants of Far North in March. It is shown that there is correlation of the vitamin D with total cholesterol, apolipoprotein A, high and low density lipoproteins and vitamin A and E.
The activity of super oxide dismutase (S), glutathione peroxidase (P), glutathione reductase (R) were analyzed 4 times during delivery (24 hour before partum, at start of the partu, immediately postpartum, and in 24 hours postpartum) in two populations of women inhabiting at 62 degrees NC (55 cases) and 69 degrees NC (40 cases) with normal delivery in January, March, June, and October. It was shown that physiological delivery did not play any significant role in S and P activity, and for these enzymes essential was the seasonal level of lipid peroxidation in North inhabitants. Activity of R in January and March was significantly lowered to the end of childbirth. Most Northern delivery women seem to have limited reserves in antioxidant enzymes function.
Lipid profile was studied in blood serum of 146 European northerns (trans-polar Nenets Autonomous district and Archangelsk). Monolayer chromatography was used to determine sphingomyelin (SP), phosphatidyl ethanolamine, phosphatidylcholine (PC), lisophosphatidylcholine, glycerophosphatides and phosphatide acides. The northerns were found to have very low concentrations of blood PC. At the same time, the NAD population have a little higher SP which may play an adaptive role in terms of the cell membrane function. The transpolar natives appear to possess an adaptive mechanism of increasing total cholesterol and reducing cholesterol of high-density lipoproteins, and activation of cholesterol esterification resulting in decrease in the free cholesterol fraction in serum.
The nutrition on alimentary and power value in the term active duty soldier on the North on norm No 1 (troop ration) approaches to calculated sizes (with the exception of fat deficiency) that allows to support the physical working capacity and the body mass index on high enough level. However insufficient content of vitamins (polyhypovitaminosis) in organisms of most of studied persons was revealed. The dynamics of change of nutrition status in the soldiers on the North during year shows essential dependence on the weather rigidity parameters and the seasonal factor.
Complex investigations of adolescences (14-15 years) residing on the European North at 62 and 65 degrees latitudes have been carried out. It was shown that the latitude factor on the North affected on mature organism of adolescences already at a difference of residence place on 3 degrees. The decrease of tolerance to hypoxemia, quality of hemodynamic regulation at short-term physical activity, physical health level, nervous processes rate (switching of attention) and the increase of plasma lactate level (attribute of hypoxia) were shown in adolescences residing at higher latitudes. The sexual distinctions and features of northerner organism on a lot of parameters in adolescences were revealed.
In the present work four examinations (January, March, June, October 1991-1992) of the blood concentration of adrenal hormones (cortisol) and thyroid hormones (triiodothyronine (T3) and thyroxine T4) and their dependence on space and terrestrial weather parameters have been done for large groups of healthy inhabitants of high latitudes (Svalbard, the most northerly in the world year-round inhabited settlements). The aim of this study was to find the possible sensitivity of these biochemical parameters to variations of external natural factors at high latitudes in three independent groups of people living in this region (miners and people working underground (364 samples), the men working on the ground (274 samples) and women working on the ground (280 samples)). The obtained data indicate that the most expressed dependence of concentration of the three studied hormones is on the level of geomagnetic activity (GMA) - Kp, Ap, Kpmax - 3h. For two of the four seasons (June and October) with increasing levels of GMA a significant (p
In order to test the hypothesis about rapid involution of functional parameters in residents in the Polar region, the functional parameters in men of 20-69 years have been compared in cross-sectional study. There is a tendency to a steady decrease of height, strength indices, parameter of muscle working capacity, balancing of the body when standing on one leg, vital capacity, cardiac output, tolerance to hypoxemia, level of physical health, adrenocorticotropic hormone and testosterone levels and an increase of body mass index, index of coordination (impairment of motor coordination), time of visual-motor response, systolic and diastolic blood pressure, index of functional changes, insulin level. More pronounced decline of functions is observed in men after 50 years.
Change of the duration of the light day was shown to tell on biochemical and hormonal parameters in humans living on the North. The contents of T3 significantly increased in peripheral blood, the levels of insulin and urea decreased in March and October. Complex rearrangements of the metabolism in the course of year specific for high latitudes were revealed in humans.