We published the Canadian 2003 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema (HAE; C1 inhibitor [C1-INH] deficiency) in 2004.
To ensure that this consensus remains current.
In collaboration with the Canadian Network of Rare Blood Disorder Organizations, we held the second Canadian Consensus discussion with our international colleagues in Toronto, Ontario, on February 3, 2006, and reviewed its content at the Fifth C1 Inhibitor Deficiency Workshop in Budapest on June 2, 2007. Papers were presented by international investigators, and this consensus algorithm approach resulted.
This consensus algorithm outlines the approach recommended for the diagnosis, therapy, and management of HAE, which was agreed on by the authors of this report. This document is only a consensus algorithm approach and continues to require validation. As such, participants agreed to make this a living 2007 algorithm, a work in progress, and to review its content at future international HAE meetings.
There is a paucity of double-blind, placebo-controlled trials on the treatment of HAE, making levels of evidence to support the algorithm less than optimal. Controlled trials currently under way will provide further insight into the management of HAE. As with our Canadian 2003 Consensus, this 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of HAE was formed through the meeting and agreement of patient care professionals along with patient group representatives and individual patients.
We had the privilege of joining over 5,000 nurses attending the 24th Congress of the International Council of Nurses, held for the first time on the African continent in Durban, South Africa. The Congress inspired us to reflect on how leadership and policy directions in Canadian nursing resonate with global health challenges and opportunities. Dynamic plenary speakers from African countries inspired the conference theme: Leading Change--Building Healthy Nations. Ensuing discussions signalled shifting priorities and urgent implications for nursing leadership and programs of research in Canada and worldwide, in areas of primary healthcare renewal, nursing health human resources sustainability and health interventions for the achievement of the United Nations Millennium Development Goals (MDGs) (United Nations 2009; WHO 2008). Sharing challenges with nurses worldwide, Canadian nurses are privileged with the resources to address these challenges (CNA 2008; WHO 2008). Our experience at the Congress prompted the question: How must Canadian nurses reshape leadership priorities and agendas not only in the Canadian context, but also in the mutual interests of health for all? Reflecting upon the themes of the Congress and the leadership role of Canadian nurses, we identify three interconnected priorities: Invest our hearts, souls and resources in primary healthcare renewal. Grapple with the complexity of an equitable and sustainable global nursing human resources system. Ensure a lens of social justice through leadership, research and education for the achievement of the MDGs.